Couldn't be more excited to announce the launch of https://t.co/iJqFUSnnfj, the virtual slide site I wish had existed during my pathology residency. You can: - Order special stains to work up cases - See annotated histologic features - Prepare for exams with board-style questions

A large necrotizing granuloma in the lung showing histiocytes lining central necrosis with "ghost outlines" of dead cells. * Bug stains on FFPE tissue aren't 100% sensitive (AFB and GMS were negative in this case but sputum culture showed TB) WSI: https://t.co/h3ENwciNrQ

A case of extranodal NK/T cell lymphoma in the uterus. - Angiocentric and angiodestructive pattern - NK cell lineage more common than T cell lineage - Positive for EBER-ISH Whole slide: https://t.co/7efUiNOhpG

Here's a rare indolent skin and soft tissue lesion, "ALK-rearranged myxoid spindle cell neoplasm". It's composed of whorls of cords of bland spindle cells in a myxoid background. Positive for S100 and CD34, an unusual combination. See the whole slide: https://t.co/WvUpoE0YD7

A section from a paraganglion showing chromaffin cells with granular basophilic cytoplasm. Unlike paraganglioma, nests don't form a discrete mass but are dispersed among background structures. Whole slide: https://t.co/RB6YWPrkfp

A classic gastrointestinal stromal tumor (GIST) with wavy nuclei and a background hyalinized stroma. Slide link: https://t.co/tsW8VNjpdN

A color negative of an H&E pathology slide (spindle cell lipoma in this case)

Intro to dermpath: For those learning about skin pathology, I made a collection of labelled digital slides that covers normal histology as well as the most common diagnoses you'll see day-to-day. Check it out: https://t.co/ofkWrQfrCI

A mucocele-like lesion of the breast (extravasated acellular mucin): -> Considered benign but some cases are associated with ADH (e.g., this case) as well as in situ or invasive carcinoma -> Recommend complete excision for partially-sampled lesions https://t.co/UayqkLEHRr

Lymphomatoid granulomatosis: - Small T cells with occasional large, EBV+ B cells (arrow) - Angiocentric and angiodestructive Labelled whole slide image: https://t.co/5r2UGKEuLz

Lung lesions in a 65M. https://t.co/SBxVKbZxJQ

A 1x dermpath diagnosis. https://t.co/w2BeklX4Xe

Colon polyp, 60M:

The future is now

A case of autoimmune gastritis with an "antralized" gastric body, intestinal metaplasia, and a lymphoplasmacytic infiltrate in the lamina propria. * H. pylori infection can show similar findings, so make sure an H. pylori stain is negative. 🔬WSI: https://t.co/5GXSWOHnNI

Smooth muscle differentiation in a low grade endometrial stromal sarcoma. See the whole slide and more info: https://t.co/HwzIv2yV2p

A case of a rare nasopharyngeal tumor: This slide and more were just added to https://t.co/iJqFUSnnfj, bringing us to > 1300 cases total

Pelvic mass, 50F. No clear attachment to any organ on imaging

Uterine mass, 30F. See the whole slide at: https://t.co/Ory6sphgD2

Papillary renal neoplasm with reverse polarity: - Papillae lined by bland cuboidal cells with nuclei oriented AWAY from the basement membrane - GATA3+ See the whole slide and more info: https://t.co/3rAlL7a2Yu

Complete hydatidiform mole: - Single population of large, hydropic villi with irregular "scalloped" borders - Trophoblast proliferation, often in a circumferential pattern around villi See the whole slide and more info: https://t.co/YAOy2uJFM4