Tiago C. Luis
@TiagoCLuis
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Group leader @imperialcollege. We investigate how blood stem cells are regulated by their microenvironment in stress and malignant hematopoiesis
London, England
Joined May 2018
1/5 Our paper is out today @NatureComms. We report a new feedback mechanism by which, in response to platelet depletion, IL-1 secreted by activated platelets signals through Lepr+ niche cells to activate HSCs and restore homeostasis. @MRC_WIMM, @Karolinskainst, @ImperialImmuno.
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RT @cribdealmeida: Our new manuscript (my first as senior author 🎉). We found that the RNA helicase DDX1 controls germinal centre B-cell ma….
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Very proud of our most recent Dr Xu for getting his PhD today @ImperialImmuno. Looking forward to keep working together. Thank you also to @kamilkranc and @DrDentie for examining his thesis.
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Thank you @InvisWarriorSCD to letting us join the team. Had a great time @ExRdFestival and look forward for next year. @ImperialImmuno.
Thank you @TiagoCLuis lab for joining us at the @ExRdFestival to raise awareness for #SickleCell and spark interest in #Science. Tiago, Rose and Aisha spent many hours explaining #sicklecelldisease and #BloodCells to the visitors. #ThankYou
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RT @purton_louise: Of all the obituaries being currently prepared for Connie Eaves (incl one by @scienceadvocacy & myself), this is one you….
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RT @simoesfili: We're recruiting: 5-year postdoctoral scientist to lead work understanding how the human #heart develops. If you are into #….
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RT @MartT_babraham: To feed applied science by starving basic science is like economising on the foundations of a building so that it may b….
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5/5 Thanks to all involved on a great teamwork, and to all our collaborators.
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4/5 IL-1 signaling in Lepr+ perivascular niche cells is critical for the activation of HSCs proliferation.
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3/5 IL-1 is released upon platelet activation and depletion and is sensed by bone marrow Lepr+ perivascular stromal cells.
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2/5 We show that acute platelet depletion preferentially recruits platelet biased stem cells into proliferation to reinstate homeostasis. This process is dependent on platelet activation.
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We have an open #PhD position in our lab @imperialcollege. Join us in London to work on #stemcells,#niche, #TGFb_signaling and #regeneration. More details at Get in touch!
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RT @LabMonteiro: We are hiring! A postdoc position has become available in my lab to study epigenetic regulation of blood stem cell formati….
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RT @SThongjuea: Job opportunity! . We are seeking a postdoctoral scientist for single-cell bioinformatics. Only a week left to apply for th….
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RT @RhysMorganLab: Fully funded PhD project available with myself @SussexLifeSci @Sussex_Haem and Dr Yury Bogdanov @unisouthampton @CCI_UoS….
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Few days left to apply for a #postdoc position in my lab. Join us @ImperialImmuno, @imperialcollege London to work on #stemcells #niche in #clonal_hematopoiesis and #leukemia initiation. More details at
imperial.ac.uk
The Luis lab investigates the role of the bone marrow niches in the regulation of HSC function. Our goal is to decode the molecular cross-talk between blood stem cells and their niches, it's role in...
We are hiring a #postdoc to join my team .@imperialcollege London to work on #stemcells, #niche #clonal_hematopoiesis and #leukemia. More details at Please RT #postdocjobs
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RT @DinisCalado: Hello! Open PhD position to study "Immune cell interactions in germinal centers driven by triple n….
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We are hiring a #postdoc to join my team .@imperialcollege London to work on #stemcells, #niche #clonal_hematopoiesis and #leukemia. More details at Please RT #postdocjobs
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Great opportunity with a great supervisor. If you are interested in macrophages and cardiac regeneration this is for you 👇👇👇.
Last chance to apply, deadline tomorrow! Join us @IdrmOxford @UniofOxford.
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