The Shields Lab
@TheShieldsLab
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Focused on #SCLC | PI @drshieldsmd | #liquidbiopsy #methylation #subtypes #drugscreen | overcome #resistance | bench to bedside | IU Simon Comprehensive Cancer
Indianapolis, IN
Joined September 2023
A true giant in the field of small cell lung cancer! An absolute honor to have Dr. Anish Thomas (@NIH) as a visiting professor at @IUCancerCenter, presenting his groundbreaking research with a โreverse translationalโ approach (patient bedside to the bench, and back!) on #SCLC.
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A lifelong dream came true today. Almost exactly 25 years ago today, I lost my strong Marine father to small cell lung cancer. Lost and broken into a million pieces, I sought out Dr. John Minna as a teenager to learn how I could become a translational thoracic oncologist to
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Dr. Toby Campbell (@UWCarbone) will join @drshieldsmd (@TheShieldsLab) and LUNGevity's @nursesteagall to discuss #palliativecare and answer your questions during an interactive Facebook Live. Tune in on 10/14 by visiting https://t.co/H8jXESKsJ1
@sclcsmashers #lcsm
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FDA approves maintenance lurbinectedin + atezolizumab for extensive stage #SCLC. Approval based on phase III IMforte trial that showed adding lurbinectedin (with G-CSF) to maintenance atezolizumab improved PFS (HR 0.54) and overall survival (HR 0.73). https://t.co/xWldlCoSSQ
fda.gov
On October 2, 2025, the Food and Drug Administration approved lurbinectedin in combination with atezolizumab or atezolizumab and hyaluronidase-tqjs.
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Lots of #lungcancer powerhouses in this week's lineup of @OncoDaily's 100 Influential Women in Oncology, and with good reason! Congrats to my dear friends, @NarjustFlorezMD @drshieldsmd and @triparnasen! #LCSM
๐๐๐ ๐๐ง๐๐ฅ๐ฎ๐๐ง๐ญ๐ข๐๐ฅ ๐๐จ๐ฆ๐๐ง ๐ข๐ง ๐๐ง๐๐จ๐ฅ๐จ๐ ๐ฒ: ๐๐๐ฒ ๐๐ฉ๐ข๐ง๐ข๐จ๐ง ๐๐๐๐๐๐ซ๐ฌ ๐ญ๐จ ๐
๐จ๐ฅ๐ฅ๐จ๐ฐ ๐จ๐ง ๐๐จ๐๐ข๐๐ฅ ๐๐๐๐ข๐ ๐ข๐ง ๐๐๐๐ Last week, on August 26th, in honor of Womenโs Equality Day in the United States, commemorating the 1920 law granting
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โWhen I received my Small Cell Lung Cancer diagnosis in 2023, I didnโt face it alone. My husband Larry Brooks has been my unwavering rock, my fierce advocate, and my source of strength throughout this entire journey. Together, weโve navigated the complexities of cancer treatment,
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Thank you for such a kind comment, what an honor @blally_md! Itโs a team effort to fight this disease! โค๏ธ @SclcSMASHERS @TheShieldsLab @triparnasen @christine_lovly @LaurenByersMD @Annechiangmd @max_diehn
Meet the person who is going to eliminate SCLC!!! @drshieldsmd
https://t.co/Ty24OO4hAn
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My mentor Dr. Nasser Hanna @hannawants2ELCN penned his memoir titled, โMy Patch: A Memoirโ out NOW, trending as the TOP selling book in the Oncology category on Amazon. Incredibly grateful for such an amazing mentor to look up to, learn from, and aspire to be one day likeโฆ
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Exciting things are coming soon from @TheShieldsLab at @IUCancerCenter! #SCLC #LCSM #researchcurescancer #supportresearch
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Biopsies provide only a small snapshot of a highly heterogeneous tumor. This new study from @TheShieldsLab sheds light on #adenosquamous carcinoma (#ASC), a rare subtype of #lungcancer where over 37% of tumors have actionable targets. I know people dx with ACS, and for a long
Characterization of adenosquamous NSCLC and carcinosarcoma from @TheShieldsLab now @JTOonline. Actionable alterations (including METex14, EGFR, KRAS G12C, ALK, RET) seen in 37% of adenosquamous and in 17% of carcinosarcoma samples. https://t.co/kKTfSSPDzk
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Characterization of adenosquamous NSCLC and carcinosarcoma from @TheShieldsLab now @JTOonline. Actionable alterations (including METex14, EGFR, KRAS G12C, ALK, RET) seen in 37% of adenosquamous and in 17% of carcinosarcoma samples. https://t.co/kKTfSSPDzk
jto.org
In 2025, lung cancer remains the leading cause of cancer-related mortality in both men and women. Although the advent of immunotherapy and targeted therapies has revolutionized the treatment of...
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Yโall. I have the BEST lab. ๐ฅผ โOn Wednesdays, we wear pink.โ Surprise, surprise. My lab surprised me today for my upcoming 40th (sigh) birthday with a party, fabulous cake ๐, donuts ๐ฉ & wearing my favorite color! ๐ @TheShieldsLab at @IUCancerCenter is simply amazing!๐คฉ
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@drshieldsmd @TheShieldsLab @IUCancerCenter @IUMedSchool @IUHemOnc @IUIntMed @SclcSMASHERS @PareshKumaaar @OTtheScientist @LiveLung1 You can't sit with us...unless you are Dr. Shields!!! What an awesome team you have!
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True joy to be a guest on Upstage Lung Cancer @UpstageLungCanc podcast focused on HOPE โญ๏ธ in #SCLC! Host @HildyGrossman, colleagues Dusty Donaldson @dustywater @LiveLung1, SCLC survivor Maida Mangiameli & Ann Fish-Steagall @nursesteagall @LUNGevity @SclcSMASHERS Link ๐๐งsoon!
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๐งฌ Her Fatherโs Legacy: Why Dr. @drshieldsmd Fights for SCLC Patients ๐ค After losing her father to #SCLC, Dr. Shields turned grief into purposeโtraining under Dr. John Minna & now leading @TheShieldsLab at @IUCancerCenter + @IUMedSchool to advance #lungcancer research and care.
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Thank you Live Lung @LiveLung1 for shedding light ๐ก on such an important topic. The search for biomarkers in lung cancer, especially SCLC, is of utmost importance. How do we get the RIGHT therapy for the RIGHT patient to improve outcomes & maximize quality & quantity of life?
Lurbinectedin Research Update: Biomarkers & Breakthroughs Dr. @drshieldsmd of @IUMedSchool shares exciting #SCLC research: how find biomarkers for L-nin and how @TheShieldsLab is using liquid biopsies to learn from every patient. Precision medicine in action. @IUCancerCenter
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Thank you to Live Lung @LiveLung1 to helping spread the word on how tissue biopsies can be sometimes limited due to crush artifact & how liquid biopsies may help improve care for patients diagnosed with #SCLC
#clinicaltrials #genomics @MyaPrecisionG @SclcSMASHERS
๐ฏ Liquid Biopsies in SCLC: A Game-Changer? ๐งช @drshieldsmd of @IUMedSchool explains how @TheShieldsLab is using liquid biopsies to help track mutations in small cell lung cancerโoffering new hope where traditional biopsies fall short. #SCLC #LungCancer #LiquidBiopsy
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๐งฌ Her Fatherโs Legacy: Why Dr. @drshieldsmd Fights for SCLC Patients ๐ค After losing her father to #SCLC, Dr. Shields turned grief into purposeโtraining under Dr. John Minna & now leading @TheShieldsLab at @IUCancerCenter + @IUMedSchool to advance #lungcancer research and care.
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Lurbinectedin Research Update: Biomarkers & Breakthroughs Dr. @drshieldsmd of @IUMedSchool shares exciting #SCLC research: how find biomarkers for L-nin and how @TheShieldsLab is using liquid biopsies to learn from every patient. Precision medicine in action. @IUCancerCenter
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๐ฏ Liquid Biopsies in SCLC: A Game-Changer? ๐งช @drshieldsmd of @IUMedSchool explains how @TheShieldsLab is using liquid biopsies to help track mutations in small cell lung cancerโoffering new hope where traditional biopsies fall short. #SCLC #LungCancer #LiquidBiopsy
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