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The Shields Lab Profile
The Shields Lab

@TheShieldsLab

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Following
194
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83

Focused on #SCLC | PI @drshieldsmd | #liquidbiopsy #methylation #subtypes #drugscreen | overcome #resistance | bench to bedside | IU Simon Comprehensive Cancer

Indianapolis, IN
Joined September 2023
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@drshieldsmd
Misty Dawn Shields
2 months
A true giant in the field of small cell lung cancer! An absolute honor to have Dr. Anish Thomas (@NIH) as a visiting professor at @IUCancerCenter, presenting his groundbreaking research with a โ€œreverse translationalโ€ approach (patient bedside to the bench, and back!) on #SCLC.
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@drshieldsmd
Misty Dawn Shields
2 months
A lifelong dream came true today. Almost exactly 25 years ago today, I lost my strong Marine father to small cell lung cancer. Lost and broken into a million pieces, I sought out Dr. John Minna as a teenager to learn how I could become a translational thoracic oncologist to
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@LUNGevity
LUNGevity Foundation
2 months
Dr. Toby Campbell (@UWCarbone) will join @drshieldsmd (@TheShieldsLab) and LUNGevity's @nursesteagall to discuss #palliativecare and answer your questions during an interactive Facebook Live. Tune in on 10/14 by visiting https://t.co/H8jXESKsJ1 @sclcsmashers #lcsm
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@StephenVLiu
Stephen V Liu, MD
3 months
FDA approves maintenance lurbinectedin + atezolizumab for extensive stage #SCLC. Approval based on phase III IMforte trial that showed adding lurbinectedin (with G-CSF) to maintenance atezolizumab improved PFS (HR 0.54) and overall survival (HR 0.73). https://t.co/xWldlCoSSQ
Tweet card summary image
fda.gov
On October 2, 2025, the Food and Drug Administration approved lurbinectedin in combination with atezolizumab or atezolizumab and hyaluronidase-tqjs.
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@acmoorephd
Dr. Amy C. Moore
3 months
Lots of #lungcancer powerhouses in this week's lineup of @OncoDaily's 100 Influential Women in Oncology, and with good reason! Congrats to my dear friends, @NarjustFlorezMD @drshieldsmd and @triparnasen! #LCSM
@oncodaily
OncoDaily
3 months
๐Ÿ๐ŸŽ๐ŸŽ ๐ˆ๐ง๐Ÿ๐ฅ๐ฎ๐ž๐ง๐ญ๐ข๐š๐ฅ ๐–๐จ๐ฆ๐ž๐ง ๐ข๐ง ๐Ž๐ง๐œ๐จ๐ฅ๐จ๐ ๐ฒ: ๐Š๐ž๐ฒ ๐Ž๐ฉ๐ข๐ง๐ข๐จ๐ง ๐‹๐ž๐š๐๐ž๐ซ๐ฌ ๐ญ๐จ ๐…๐จ๐ฅ๐ฅ๐จ๐ฐ ๐จ๐ง ๐’๐จ๐œ๐ข๐š๐ฅ ๐Œ๐ž๐๐ข๐š ๐ข๐ง ๐Ÿ๐ŸŽ๐Ÿ๐Ÿ“ Last week, on August 26th, in honor of Womenโ€™s Equality Day in the United States, commemorating the 1920 law granting
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@LiveLung1
LiveLung
3 months
โ€œWhen I received my Small Cell Lung Cancer diagnosis in 2023, I didnโ€™t face it alone. My husband Larry Brooks has been my unwavering rock, my fierce advocate, and my source of strength throughout this entire journey. Together, weโ€™ve navigated the complexities of cancer treatment,
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@drshieldsmd
Misty Dawn Shields
5 months
Thank you for such a kind comment, what an honor @blally_md! Itโ€™s a team effort to fight this disease! โค๏ธ @SclcSMASHERS @TheShieldsLab @triparnasen @christine_lovly @LaurenByersMD @Annechiangmd @max_diehn
@blally_md
Brian Lally, MD
5 months
Meet the person who is going to eliminate SCLC!!! @drshieldsmd https://t.co/Ty24OO4hAn
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@drshieldsmd
Misty Dawn Shields
5 months
My mentor Dr. Nasser Hanna @hannawants2ELCN penned his memoir titled, โ€œMy Patch: A Memoirโ€ out NOW, trending as the TOP selling book in the Oncology category on Amazon. Incredibly grateful for such an amazing mentor to look up to, learn from, and aspire to be one day likeโ€ฆ
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@drshieldsmd
Misty Dawn Shields
5 months
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@jillfeldman4
Jill Feldman
5 months
Biopsies provide only a small snapshot of a highly heterogeneous tumor. This new study from @TheShieldsLab sheds light on #adenosquamous carcinoma (#ASC), a rare subtype of #lungcancer where over 37% of tumors have actionable targets. I know people dx with ACS, and for a long
@StephenVLiu
Stephen V Liu, MD
5 months
Characterization of adenosquamous NSCLC and carcinosarcoma from @TheShieldsLab now @JTOonline. Actionable alterations (including METex14, EGFR, KRAS G12C, ALK, RET) seen in 37% of adenosquamous and in 17% of carcinosarcoma samples. https://t.co/kKTfSSPDzk
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@StephenVLiu
Stephen V Liu, MD
5 months
Characterization of adenosquamous NSCLC and carcinosarcoma from @TheShieldsLab now @JTOonline. Actionable alterations (including METex14, EGFR, KRAS G12C, ALK, RET) seen in 37% of adenosquamous and in 17% of carcinosarcoma samples. https://t.co/kKTfSSPDzk
jto.org
In 2025, lung cancer remains the leading cause of cancer-related mortality in both men and women. Although the advent of immunotherapy and targeted therapies has revolutionized the treatment of...
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@drshieldsmd
Misty Dawn Shields
6 months
Yโ€™all. I have the BEST lab. ๐Ÿฅผ โ€œOn Wednesdays, we wear pink.โ€ Surprise, surprise. My lab surprised me today for my upcoming 40th (sigh) birthday with a party, fabulous cake ๐ŸŽ‚, donuts ๐Ÿฉ & wearing my favorite color! ๐Ÿ’• @TheShieldsLab at @IUCancerCenter is simply amazing!๐Ÿคฉ
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@LUNGevity
LUNGevity Foundation
6 months
@drshieldsmd @TheShieldsLab @IUCancerCenter @IUMedSchool @IUHemOnc @IUIntMed @SclcSMASHERS @PareshKumaaar @OTtheScientist @LiveLung1 You can't sit with us...unless you are Dr. Shields!!! What an awesome team you have!
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@drshieldsmd
Misty Dawn Shields
6 months
True joy to be a guest on Upstage Lung Cancer @UpstageLungCanc podcast focused on HOPE โญ๏ธ in #SCLC! Host @HildyGrossman, colleagues Dusty Donaldson @dustywater @LiveLung1, SCLC survivor Maida Mangiameli & Ann Fish-Steagall @nursesteagall @LUNGevity @SclcSMASHERS Link ๐Ÿ”—๐ŸŽงsoon!
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@drshieldsmd
Misty Dawn Shields
6 months
Thank you to Live Lung @LiveLung1 for sharing my life story and my โ€œwhy.โ€ #LCSM @SclcSMASHERS
@LiveLung1
LiveLung
6 months
๐Ÿงฌ Her Fatherโ€™s Legacy: Why Dr. @drshieldsmd Fights for SCLC Patients ๐Ÿค After losing her father to #SCLC, Dr. Shields turned grief into purposeโ€”training under Dr. John Minna & now leading @TheShieldsLab at @IUCancerCenter + @IUMedSchool to advance #lungcancer research and care.
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@drshieldsmd
Misty Dawn Shields
6 months
Thank you Live Lung @LiveLung1 for shedding light ๐Ÿ’ก on such an important topic. The search for biomarkers in lung cancer, especially SCLC, is of utmost importance. How do we get the RIGHT therapy for the RIGHT patient to improve outcomes & maximize quality & quantity of life?
@LiveLung1
LiveLung
6 months
Lurbinectedin Research Update: Biomarkers & Breakthroughs Dr. @drshieldsmd of @IUMedSchool shares exciting #SCLC research: how find biomarkers for L-nin and how @TheShieldsLab is using liquid biopsies to learn from every patient. Precision medicine in action. @IUCancerCenter
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@drshieldsmd
Misty Dawn Shields
6 months
Thank you to Live Lung @LiveLung1 to helping spread the word on how tissue biopsies can be sometimes limited due to crush artifact & how liquid biopsies may help improve care for patients diagnosed with #SCLC #clinicaltrials #genomics @MyaPrecisionG @SclcSMASHERS
@LiveLung1
LiveLung
6 months
๐ŸŽฏ Liquid Biopsies in SCLC: A Game-Changer? ๐Ÿงช @drshieldsmd of @IUMedSchool explains how @TheShieldsLab is using liquid biopsies to help track mutations in small cell lung cancerโ€”offering new hope where traditional biopsies fall short. #SCLC #LungCancer #LiquidBiopsy
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@LiveLung1
LiveLung
6 months
๐Ÿงฌ Her Fatherโ€™s Legacy: Why Dr. @drshieldsmd Fights for SCLC Patients ๐Ÿค After losing her father to #SCLC, Dr. Shields turned grief into purposeโ€”training under Dr. John Minna & now leading @TheShieldsLab at @IUCancerCenter + @IUMedSchool to advance #lungcancer research and care.
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@LiveLung1
LiveLung
6 months
Lurbinectedin Research Update: Biomarkers & Breakthroughs Dr. @drshieldsmd of @IUMedSchool shares exciting #SCLC research: how find biomarkers for L-nin and how @TheShieldsLab is using liquid biopsies to learn from every patient. Precision medicine in action. @IUCancerCenter
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@LiveLung1
LiveLung
6 months
๐ŸŽฏ Liquid Biopsies in SCLC: A Game-Changer? ๐Ÿงช @drshieldsmd of @IUMedSchool explains how @TheShieldsLab is using liquid biopsies to help track mutations in small cell lung cancerโ€”offering new hope where traditional biopsies fall short. #SCLC #LungCancer #LiquidBiopsy
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