JHLT
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The official account for the Journal of Heart and Lung Transplantation. Latest research on HF, Heart/Lung Tx, MCS, and PH.
Joined May 2015
Patients with #CTEPH and atrial fibrillation (#AFib) have a dominant left heart disease profile. AFib doesn’t increase mortality in patients with CTEPH. @KopecGrzegorz . 🔗:
jhltonline.org
Atrial fibrillation (AFib) reduces the quality of life and increases hospitalization frequency in patients with pulmonary hypertension (PH). Chronic thromboembolic pulmonary hypertension (CTEPH) is a...
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Consensus statement by Kobashigawa & Zuckermann et al. reviews evaluation/management of circulating #antibodies before & after #HeartTx, and antibody-mediated rejection. @SmidtHeart @ManlaYosef . 🔗:
jhltonline.org
The understanding of circulating antibodies and their relationship to antibody-mediated rejection (AMR) has yet to be fully elucidated in heart transplantation. Circulating antibodies are important...
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🧵 Read this interesting commentary on Direct procurement of lungs with A-NRP by Dr. Cain ⤵️ #Editorial. 🔗:
jhltonline.org
Since its introduction to the field over three decades ago, donation after circulatory death (DCD) lung transplantation has shouldered a unique role as one primary pathway for expansion of the donor...
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Use of lungs after Abdominal NRP is expanding. 🫁 Read this article to learn more about UK's experience and short-term outcomes. #ANRP @LukeJLWilliams . 🔗:
jhltonline.org
Abdominal Normothermic Regional Perfusion (A-NRP) improves outcomes for transplanted abdominal organs from Donation after Circulatory Death (DCD) donors. Concerns have been raised about the effect of...
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Listen anywhere you get your podcasts, or at the link here:
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Luke Williams, a cardiothoracic surgery trainee at Royal Papworth Hospital, is on JHLT the Podcast to discuss the use of DCD lungs alongside abdominal normothermic regional perfusion.
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Today on #JHLTThePodcast: Luke Williams of @RoyalPapworth explores the UK experience with controlled #DCD direct procurement of #lungs with concomitant abdominal #NRP. How do survival rates differ and what might they imply about #PrimaryGraftDysfunction?
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🧵 Comprehensive review and #editorial on the history and use of Donor Care Units in the United States. ⤵️. 🔗:
jhltonline.org
Recently, there has been a national push to create donor care units (DCU) both within and outside hospital settings due to the increasing need for intensive care unit (ICU) beds, along with the...
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In a retrospective study of 4,668 adult deceased organ donors after brain death managed in US donor care units (DCUs), #HeartTx survival & heart donation were similar between hospital-based and independent DCUs (even after adjustment). 🫀 @PennLDI. 🔗:
jhltonline.org
Despite growing prevalence, the impact of centralized deceased organ donor care units on heart donation and transplant recipient outcomes remains unknown.
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Young children may particularly benefit from cardiac #xenotransplantation given the lack of alternatives. As advances in the field continue, medical & ethical considerations will be required for implementation. #PedsTx @surschel1 . 🔗:
jhltonline.org
With recent advances in xenotransplantation, an increased initiative toward clinical applications in human recipients has evolved. Along with this trend, ethical concerns and considerations have been...
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Using unbiased, whole transcriptome single-cell RNA-sequencing, researchers identify unique circulating cell-specific gene expression profiles in high-grade #CAV that have potential to serve as #biomarkers. @KAmancherla . 🔗:
jhltonline.org
Cardiac allograft vasculopathy (CAV) is the leading cause of late graft failure and mortality after heart transplantation (HT). Current strategies for early diagnosis and effective treatment of CAV...
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🧵 Check out this #editorial reviewing temperature-controlled hypothermic preservation. ⤵️. 🔗:
jhltonline.org
Static cold storage (SCS) of donor hearts is still the most used preservation method worldwide. Cooling begins in the donor, where cold preservation solution at near 0°C is introduced through an...
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This study reveals #SherpaPak temperature-controlled heart preservation maintains metabolic homeostasis & modulates gene expression to potentially reduce primary graft dysfunction for better #transplant outcomes. #OrganPreservation @UTSWHear, @GauravSharmaPhD, @matthias_peltz.
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Listen anywhere you get podcasts, or visit the link below: .
ishlt.org
Hear about how temperature storage affects donor hearts on a molecular level from Gaurav Sharma of the University of Texas Southwestern Medical Center on JHLT: The Podcast.
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Today on #JHLTThePodcast: Gaurav Sharma, PhD, MBA joins to discuss #metabolic and #transcriptomic insights on #donorhearts with temperature controlled hypothermic preservation versus conventional static cold storage. #HeartTx #Perfusion #Cardiology #CTSurgery
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🧵Is the Kidney Safety Net policy helping our #lungtransplant patients? Check out this opinion piece on this important topic! #Editorial . 🔗:
jhltonline.org
Lung transplant is the only treatment option for many patients with advanced lung disease. As more patients are added to the waiting list, and novel technologies are introduced to support recipients...
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How does the kidney safety net policy benefit #LungTx patients? Since 2023, only 2.1% of 🫁 recipients were eligible for a rescue kidney and had only a 42% 1-year survival. @JenkinsRee91433 . 🔗:
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The power of the #ISHLTTransplantRegistry is shown again! Nowhere else is there this kind of “n” Early dialysis after thoracic transplantation is associated with a >40 % risk of death in year 1 post #TTX. @rcogswell_umn . 🔗:
jhltonline.org
This special report from the International Society for Heart and Lung Transplantation (ISHLT) International Thoracic Organ Transplant (TTX) Registry is focused on incidence, risk factors, and...
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🧵 Check out this expert commentary from Dr. Benden on outcomes of living donor #lungtransplantation. 🫁 #Editorial. 🔗:
jhltonline.org
Dr. Morimura and colleagues from Japan published a national multi-center retrospective study examining the clinical data of children who underwent lung transplantation (LTx) at three Japanese centers...
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