JHLT
@TheJHLT
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The official account for the Journal of Heart and Lung Transplantation. Latest research on HF, Heart/Lung Tx, MCS, and PH.
Joined May 2015
Stefan Schwarz, MD, PhD, of @MedUni_Wien is on the #JHLT podcast to discuss #LungTransplant in patients w/suspicious lung lesions. What methods are used to assess the probability of malignancy—and what can we learn about standards in clinical practice from this discussion?
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Perfect for DIY projects, car mounts, LED lights, and more. All around here: https://t.co/mLO3gXTWnK Tap the video button or see the comments to get more info.
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🚨 The @ISHLT Transplant Registry is BACK and better than ever! 🚨 Dive into the latest annual report revealing key trends: 🔼 Temporary #MCS & #ECMO for #HT 🔼 #DCD heart & lung transplants 🔽 #LungTransplants for cystic fibrosis down Don’t miss these game-changing insights!
jhltonline.org
In this 2025 International Society for Heart and Lung Transplantation (ISHLT) Thoracic Organ Transplant (TTX) Registry Annual Report, we present the first new data since the Registry paused in 2018...
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@Raynaud_Maths @drAntoineRoux @AlexandreLoupy From ALAD to BLAD to CLAD... what are the experts saying in lung transplant? 🔗:
jhltonline.org
The natural history of lung function after lung transplantation has been described in snapshots since the first successful procedures in the 1980’s. In general, 4 main lung function time-periods may...
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For the first time, @ISHLT published a consensus statement on the referral and selection of #pediatric #LungTx candidates. A panel of international experts developed recommendations in the care of children with advanced lung disease in need of lung transplantation. @LungTxp 🫁
jhltonline.org
Children with advanced lung diseases are eligible to be considered as potential candidates for lung transplantation around the world. The timing of referral, evaluation, determination of candidacy,...
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A new study identifies 7 distinct FEV1 trajectories post #LungTransplantation, each telling a different story of survival- should we consider personalized, trajectory-based monitoring of lung recipients? 🫁 @Raynaud_Maths, @drAntoineRoux, @AlexandreLoupy 🔗:
jhltonline.org
We identified and validated FEV1 trajectories that capture different clinical scenarios associated with post-transplant recipient outcomes. Our results may provide the basis for a trajectory-based...
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First-ever cardiac transplant using a donor heart procured after MAiD (Medical Assistance in Dying): a milestone in expanding the donor pool. Donation after circulatory death offers new hope for patients on the transplant waitlist. 🫀 #HeartTransplant #DCD #MAiD @MoAbdullahCTS,
jhltonline.org
Medical assistance in dying (MAiD), was decriminalized in Canada in 2016. MAiD permits competent adults with intolerable suffering from a serious incurable illness, disease or disability access to...
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Can we move from reactive rescue to proactive unloading in SCAI stage B #cardiogenicshock? In this #JHLT letter, authors explore how istaroxime may mark a paradigm shift. #heartfailure @drgreen78 🔗:
jhltonline.org
We read with great interest the editorial by Ortega-Hernández and Hernández-Montfort1 on the Safety and Efficacy of Istaroxime for Pre-Cardiogenic Shock Management (SEISMiC) trial and the potential...
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Research shows that plasma is critical to quality of porcine hearts perfused with blood products for up to 4 h. Banked blood helps address challenges having quality fluids available for ex vivo #heart perfusion. 🫀 @acker_jason 🔗:
jhltonline.org
Normothermic ex vivo organ perfusion holds promise for increasing the organ donor pool; however, standard use of autologous whole blood (WB) presents logistical and functional challenges. This study...
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REMINDER: 📢 #JHLT is accepting papers focused on device therapies for advanced #HeartDisease & #LungDisease for a special 2026 issue. ✍️🫀🫁 Submit by 30 December 📆🔗
ishlt.org
JHLT, an official publication of the ISHLT, will release a special issue in March 2026 dedicated to manuscripts exploring device therapies in advanced heart and lung disease. Submissions are accepted...
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An automated, machine learning approach can quantify the function of ex-vivo beating hearts to help guide donor selection. #transplant #OHT @BrianC_Ayers, @mghctsurgery, @MGHSurgery 🔗:
jhltonline.org
There is not a reliable biomarker for identifying which hearts are at highest risk for primary graft dysfunction. We hypothesize that ex-vivo video kinematics (EVVK) of unloaded beating hearts can...
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🌍✋💔 No Hearts Left Behind: We propose a global transplant exchange to rescue unused donor hearts. Technology enables it—ethics demand it. A call to action for #TransplantEquity 🔗:
jhltonline.org
Despite technological and logistical progress in heart transplantation, thousands of viable donor hearts are still discarded annually—particularly in the United States—while patients elsewhere...
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DSA in lung transplant recipients is linked to lower post-transplant lung function, higher risk of BLAD, CLAD (esp. RAS), and increased mortality. DSA can be used to stratify risk for BLAD #LungTransplant @MohtadyNababteh 🔗:
jhltonline.org
Our study demonstrates that DSA development significantly impairs post-transplant lung function and increases the risk of BLAD even in the absence of clinical AMR. These findings suggest that DSA may...
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@kurt_prins 🧵 Paving the way for precision therapies for PAH-associated myopathy and exercise intolerance. #PAH 🔗:
jhltonline.org
Commentary on:
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Multi-omic profiling identifies new targets for treatment and biomarkers of #PAH-associated myopathy and exercise intolerance. @kurt_prins 🔗:
jhltonline.org
Pulmonary arterial hypertension (PAH) is a rare but debilitating condition that causes exercise intolerance and ultimately death. Skeletal muscle derangements contribute to depressed exercise...
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A Vanderbilt University Medical Center team is pioneering the use of minimally invasive transcatheter tricuspid valve replacement to resolve severe tricuspid regurgitation, a rare and serious posttransplant complication. @kashishgoelmd @TheJHLT
https://t.co/oLS2QLL81y
news.vumc.org
The team used an artificial tricuspid valve, EVOQUE, which received Food and Drug Administration approval in February.
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Description of a novel approach to Heart-Lung Transplantation, using ex vivo normothermic perfusion after #DCD to preserve an intact heart-lung bloc. DCD and novel preservation approaches can expand the heart-lung donor pool for patients requiring this therapy. 🫀🫁 🔗:
jhltonline.org
Combined heart-lung transplant (HLT) peaked globally in 1989–1990 with a subsequent fall in case numbers; however, there has been a steady increase in the number of HLTs performed in the United...
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🚨 #JHLT Call for Papers 🚨 #JHLT is accepting submissions for a special 2026 issue focused on device therapies for advanced #HeartDisease & #LungDisease. 🫀🫁 Papers will be accepted until 30 December. 📅
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🧵 "Beyond Cold Storage: Rise of the Machines" - A thoughtful #editorial on understanding the history and rapidly evolving use of machine perfusion in #organprocurement. 🔗:
jhltonline.org
In 1978, the transplant team at the Medical College of Virginia in Richmond published the first case series of six long distance transport of donor hearts from donation after brain-death (DBD)...
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