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Tangram Therapeutics Profile
Tangram Therapeutics

@TangramTx

Followers
533
Following
42
Media
102
Statuses
286

Relentless medicine discovery.

London, England
Joined May 2015
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@TangramTx
Tangram Therapeutics
19 hours
We’ve announced our first CTA submission, advancing TGM-312 for MASH into the clinic. Discovered in-house and backed by robust preclinical data, TGM-312 shows potential as a truly differentiated treatment option for people living with MASH. Find out more: https://t.co/UePz2J72OA
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@TangramTx
Tangram Therapeutics
16 days
Our GalOmic siRNA, TGM-312 for the treatment of MASH, has shown outstanding data in Gubra’s highly translatable GAN DIO-MASH model and is now advancing toward a CTA submission in Q4 2025. If you're at #TIDESEurope, attend our presentation to find out more.
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@TangramTx
Tangram Therapeutics
2 months
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@TangramTx
Tangram Therapeutics
2 months
e-therapeutics has relaunched as Tangram Therapeutics and simultaneously unveiled our next-generation AI platform LLibra OS. We're poised to unlock the true promise of RNAi medicines as we progress towards the clinic by the end of 2025.
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@TangramTx
Tangram Therapeutics
5 months
We've announced significant progress on ETX-312, our lead GalOmic therapy for MASH: ✅ Positive non-clinical data with ETX-312 well tolerated across all dose levels ✅ On track for CTA submission in Q4 2025 Find out more here:
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tangramtx.com
ETX-312 well tolerated at exaggerated dose levels in GLP-compliant toxicology studies GMP manufacturing of clinical trial batch successfully completed On track for CTA submission in Q4 2025 London,...
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@TangramTx
Tangram Therapeutics
10 months
On Friday we presented our preclinical data on ETX-148 in haemophilia at @EAHADnews! It was a great opportunity to learn more about the latest advancements in the space and share our own data with the bleeding disorders community.
@EAHADnews
EAHAD
10 months
Final SLAM speakers Sidonio Jr, Frenzel, and Pursell report back on the use of prothrombin complex concentrate with non-factor therapies, dose escalation outcomes in novel treatment trials, and preclinical safety & efficacy data for emerging therapies in #haemophilia A&B
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@TangramTx
Tangram Therapeutics
1 year
We are progressing towards the clinic! 🚀 Find out about our latest progress towards becoming a clinical-stage company and continued development of our HepNet platform in our business update and interim results, published today: https://t.co/U5LNahPwXW #RNAi #AI #Biotech
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@TangramTx
Tangram Therapeutics
1 year
We are looking forward to presenting new data from our GalOmic therapeutic pipeline at upcoming scientific conferences! Find out more here: https://t.co/YdtVyMJiqe #RNAi #siRNA #MASH #Cardiometabolic #Biotech #AI
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@TangramTx
Tangram Therapeutics
1 year
Today, #ETX-sponsored Bodhana met with @RachelReevesMP at Downing Street as she prepares to represent England in the upcoming Chess Olympiad at just 9 years old. Good luck from everyone at ETX! #chess #biotech
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@TangramTx
Tangram Therapeutics
1 year
We are extremely proud of #ETX-sponsored chess prodigy Bodhana who, at just 9 years old, will be the youngest person to represent England in an international sporting competition when she plays in the Chess Olympiad in September! https://t.co/bQMdp6XynN #biotech #chess #AI
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theguardian.com
Bodhana Sivanandan, from Harrow, will take on adults on the world stage after being picked to play for at the world Chess Olympiad
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@TangramTx
Tangram Therapeutics
1 year
We are pleased to announce our final results for the 2023/24 financial year, alongside some exciting pipeline updates! Find out more here: https://t.co/yDbJ5ca0PW $ETX #RNAi #AI #Biotech
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@TangramTx
Tangram Therapeutics
2 years
Just announced: Lord David Prior has joined as Chair of our Board of Directors! David's insights from his extensive healthcare experience will be invaluable as we progress our GalOmic™ therapies towards the clinic. Find out more: https://t.co/1H4aPj3qh7 #RNAi #AI #Biotech
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@TangramTx
Tangram Therapeutics
2 years
Just announced: We've raised £28.9m and are planning to delist from London’s #AIM. Proceeds from the fundraise will enable continued progression of our #RNAi assets towards the clinic and accelerated development of our #AI approaches! Find out more: https://t.co/jZ5GImpqzu $ETX
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@TangramTx
Tangram Therapeutics
2 years
~480M people with #MASH worldwide have no approved treatment options. ETX-312 shows significant therapeutic benefit in a translatable #MASH model alone and in combination with other mechanisms of action including #GLP1 agonists. Learn more: https://t.co/JUPtWuyR10 #biotech #RNAi
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@TangramTx
Tangram Therapeutics
2 years
In case you missed it: we’re progressing GalOmic #RNAi assets ETX-312 for MASH and ETX-407 for Dry AMD to IND-enabling studies! Find out more about this and other recent progress in our business update: https://t.co/k4irONEI7Z $etx #biotech #MASH #AMD
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@TangramTx
Tangram Therapeutics
2 years
ETX is advancing its pipeline of GalOmic #RNAi assets towards the clinic, with novel targets identified in-house leveraging HepNet’s proprietary datasets and advanced analytics. Find out more in this morning's business update: https://t.co/k4irONEair $etx #biotech #AI #LLMs
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@TangramTx
Tangram Therapeutics
2 years
#ETX are proud sponsors of Bodhana Sivanandan who won both the Women’s and Under-12 prizes in the European Blitz Chess Championship last week, finishing top of the English contingent at just 8 years old! What an achievement. https://t.co/8c6ofszwbY #chess #RNAi #AI #biotech
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@TangramTx
Tangram Therapeutics
2 years
Our CEO Ali Mortazavi is presenting at the LSX Inv€$tival Showcase on Monday! Learn more about our #AI-driven approach to #RNAi medicines on the Healthtech & Techbio stage at 13:45. Reach out at https://t.co/ef2ZbfuFzl to connect during the showcase #biotech #LLM #RNAi
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@TangramTx
Tangram Therapeutics
2 years
We've announced a collaboration with Arcturis to integrate its Real-World Evidence into HepNet, supporting development of #RNAi therapies for metabolic dysfunction and fatty liver disease. Find out more here: https://t.co/RGd1CF4tYp $etx #biotech #AI #LLMs
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