RT @benmpeter: Today is a very big day for our research group, with two of my students, @arevsumer and @IasiLeonardo publishing papers on….

RT @IasiLeonardo: Out today in @sciencemagazine, we've journeyed into our shared history with Neandertals by analyzing over 300 present-day….

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RT @ElenaIreneZ: Interested in sedaDNA, aDNA, or forensic genetics? . Join me in Copenhagen! . I'm hiring a PhD and a Postdoc to start in 2….

RT @jjhublin:

RT @PopliRatan: PCA and F-statistics are routinely used in population genetic studies. We provide a statistical framework to combine them i….

RT @iosif_lazaridis: Congratulations to Ali Akbari.@aliakbari23.on his amazing new work on selection in Western Eurasia that is finally rel….

RT @FossilHistory: The first Neanderthal DNA sequence was published #OnThisDay in 1997. It suggested Neanderthals did not interbreed with m….

RT @evolutionscribe: This is a big deal--a second high quality Denisovan genome has been sequenced, and it's old!.The most ancient human ge….

RT @FSanchezQuinto: Casi 20 generaciones de la @lcgunam presentes en #SMBE2024! Un honor ser parte de esta gran iniciativa que transformado….

Many thanks to @jfkelso for giving me the opportunity to co-advise Yaniv on this work, and congratulations to Yaniv for this very thorough analysis for the first chapter of his PhD thesis! 7/7.

Yaniv has made all his code for the analyses available (, which we hope will be useful. 6/7.

Yaniv proposes a solution to correct this bias, improving the accuracy of Y phylogeny reconstruction and age estimates of ancient samples. Accounting for this bias may also enable future studies of potential changes in Y mutation rate or paternal generation time. 5/7.

Some regions of the Y chromosome evolve much faster than any other regions in the genome, making reference bias particularly impactful on the Y chromosome compared to other chromosomes. 4/7.

Reference bias, where sequencing reads with non-reference alleles are less likely to align to the reference genome, is the main factor contributing to branch length variation, concealing mutations in Y chromosomes that are highly diverged from the reference used for alignment 3/7.

Yaniv tested previous hypotheses to explain this branch length variation and, while we cannot exclude that there may have been variation in mutation rate and generation time, they cannot account for the magnitude of the observed variation. 2/7.

Check out Yaniv's fantastic preprint revealing that reference bias is the major source of branch length variation in human Y chromosome lineages:

RT @_JBallesterosV: Come to my poster on exploring genetic diversity in the Americas through ancient whole genomes. I’m eager to discuss an….

RT @NiallPC: Very happy that the new paper on imputation and selection in ancient Japan, from myself, @shige_nakagome and our collaborator….

RT @oliveira_srs: Do you use Local Ancestry Inference (LAI)? Wanna know how much error to expect given source divergence or time since admi….