Our special issue on Diabetes and Bone Health is officially online! Check out the latest on this timely topic.

A new study using micro-CT imaging to demonstrate a larger cortical osteocyte lacunar volume in patients with type 2 diabetes mellitus and microvascular disease compared with patients without MVD #openaccess #ASBMR @Snapastian @eth_bone @frost_nielsen https://t.co/8H4w7MO2ep

Finally, we show that lacunar volumes are smaller in the compact bone compared to the spongy bone in participants with type 2 diabetes. However, when comparing to published data on healthy individuals it is the opposite indicating a decrease of lacunar volume with T2D

Additionally, the density of these lacunae in the trabecular bone was associated with blood sugar levels in type two diabetes, independently of MVD.

Lacunae were more spherical (round) and of a greater volume which may be an indication that osteocytes, the cells which live in these lacunae, are losing the ability to sense mechanical stimuli.

@EvaWoelfel We found that in the compact bone of individuals with microvascular disease and type 2 diabetes, the size and shape of these lacunae were altered compared to individuals with type 2 diabetes but without microvascular disease.

@EvaWoelfel In this study we investigated the effect of microvascular disease in type 2 diabetes on the bone structure. We looked at tiny voids in the bone matrix called osteocyte lacunae, which contribute to sensing mechanical forces and maintaining bone health.

And @EvaWoelfel!

Study out: In collab. with @eth_bone we found an increased osteocyte lacunar volume in type two diabetic individuals with microvascular disease. Thanks for everyone participating in this study! Click on the link for more infos: https://t.co/ijS9YGaoGR

🚨The @ISBM_society 2024 congress website is live! 9/30 to 10/3 (Toronto), right after @ASBMR. Keynote @ProfCJHernandez. NEW Malluche ECI travel award program.✈️Great speakers, presentation opportunities, networking events, workshops, etc.🦴See you there! https://t.co/Fl7nYfCJbG

Join our next ISBM ECI webinar with our Aussie Speaker :) @michbal19 "Intravital Imaging of osteoclasts reveals novel osteoclast fate and treatment response" Register below! #osteoclast🦴#osteoporosis #Cool_live_imaging 👌

New post on our website with more about our recent time in the UK for @ECTS_soc congress and FIDELIO project meeting!

Senescence may contribute to diabetic bone disease by impairing bone remodeling and repair mechanisms, @mkassem highlighting the importance of addressing cellular aging in diabetes! #senescence #diabetes #bonedisease @KMEBLab @FIDELIO_ITN

Great presentation from @NeashanMathavan about the use of Polg mice for a model of age-related fracture healing delay.

Do you want to be part of our new Spatial Imaging Consortium? We support researchers in applying the newest molecular and digital imaging techniques to their research. Research Technician: https://t.co/bsCwlMoclI Laboratory Manager: https://t.co/WF6jsDZ3I5

New exciting facilities are opening - do you want to be part of our team in Odense?

Last week ESRs went on a trip to #Hamburg to learn about the fundamentals of mechanical testing, mechanobiological principals and computational modelling of bone at our partners @UKEHamburg and @Philips #diabetes #bone #Endotwitter @MSCActions @MscaManagement