Siobhan Creanor
@SiobhanCreanor
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Looking for a career that allows you to stretch your intellectual muscles as well as make a positive difference to patient & public health? CTUs across the Network are recruiting to a variety of roles. Find out more here: https://t.co/ReRbCuqydY
#UKCTUNetwork #ClinicalTrials
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Randomized trials in individual patients – N of 1 #RCTs - remain underutilized. This @AnnalsofIM paper describes our initial experience with 57 N of 1 RCTs. In 15, results prompted patients and clinicians to alter their treatment plans. https://t.co/Ek95OYWqjM
pubmed.ncbi.nlm.nih.gov
We interpret the results as supporting the feasibility and usefulness of n-of-1 trials in clinical practice.
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📢 Call for Papers! Keele CTU Director Dr Ivonne Solis-Trapala is co-editing a BMC collection on decentralised clinical trials and digital health systems. Researchers are invited to submit their work and help advance innovation in this evolving field. 🔗 https://t.co/ISbrccJM06
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"Who gets left out of clinical research — and why it matters for us all". Don’t miss HRB-TMRN colleague Prof. Frances Shiely's powerful opinion piece on inclusivity in clinical trials in the Irish Examiner. Read it here: https://t.co/UcAanAd8mw
@UCCResearch @Galway_Research
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Advocates suggest administrative real-world data can substitute for #RCTs and offer propensity matching to reduce bias. But results often fail to correspond: #BMJ study showed direction of effect differed in 31% & CI failed to include #RCT estimate in 56% https://t.co/0s13BoheFu
pubmed.ncbi.nlm.nih.gov
Studies of routinely collected health data could give different answers from subsequent randomized controlled trials on the same clinical questions, and may substantially overestimate treatment...
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Over recent weeks I’ve heard about some trials struggling with the phenomenon known as “Lasagne’s Law.” I’ve flagged this issue before, but always good to revisit it and discuss what can be done to minimise it 1/7 #MethodologyMonday #121
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NEW PREPRINT "Critical Appraisal of Fairness Metrics in Clinical Predictive AI" -> https://t.co/TpmpXSrJN6 We identified 62 fairness metrics (& growing) - unsurprisingly it's all a bit of a mess...with most metrics not fit for purpose #predictiveAI #fairness #machinelearning
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Want to improve your knowledge & practice of clinical trials? #UKCTUNetwork members offer a wide variety of learning & development opportunities covering all aspects of academic clinical research. Find out more here: https://t.co/y0ZCQRbIM7
#ClinicalTrials #Training
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Looking for a career that allows you to stretch your intellectual muscles as well as make a positive difference to patient & public health? CTUs across the Network are recruiting to a variety of roles. Find out more here: https://t.co/ReRbCuqydY
#UKCTUNetwork #ClinicalTrials
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150 Participants! 🎉 The #DEXACELL trial has hit a fantastic milestone! Well done to @NCAresearchNHS for enrolling the 150th participant – your dedication has earned you our milestone award! Your prize is on its way. 🥳 Thank you to all sites for your incredible efforts!
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One of the trial designs that has been cropping up in discussions recently is the cluster randomised crossover, or CRXO, design. But when is it best used & what are the key issues to look out for? 1/7 #MethodologyMonday #119
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Through open collaboration sharing best practice, the #UKCTUNetwork supports member Clinical Trial Units in deliver high-quality, investigator-led non-commercial clinical trials in the UK and overseas. Learn more: https://t.co/E8YMNFTzxT
#ClinicalTrials #ICTD2025 #CTD2025
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This #ICTD @NIHRresearch celebrates how research saves lives and helps our economy grow. But for research to work for everyone, we need everyone to take part. It’s easy, safe and convenient. Join me, sign up to #BePartOfResearch today https://t.co/ejrcTEonzc
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It's International Clinical Trials Day! ExeCTU thanks all our trial participants, investigators and site staff – without you, our trials couldn’t happen! 🙏 Find out how you can Be Part of Research https://t.co/niqRpzpPZE
#ICTD2025 #HealthResearch #CTD2025 #UKCTUNetwork
bepartofresearch.nihr.ac.uk
Find out how you can take part in health and care research through Be Part of Research #BePartofResearch
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📣As it is #Internationalclinicaltrialsday, here is a timely reiminder to save the date for our International Clinical Trials Methodology Conference (ICTMC) 2026, which will be held in Birmingham, UK. We are looking forward to this already!
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🌍For #InternationalClinicalTrialsDay, we are raising awareness about the life-changing impact of clinical research. 🫶Here, some of our #ResearchParticipants share their perspectives on why it is important to #BePartofResearch
https://t.co/a0HBMmhZk4
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Behind every breakthrough are those who take part. On #ICTD2025, we thank the thousands of trial participants helping make better treatments possible. Find out how you can Be Part of Research here: https://t.co/M4aTnEvYmU
#ClinicalTrialVolunteers #UKCRC #UKCTUNetwork #CTD2025
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Today is Clinical Trials Day! We want to celebrate the role that our volunteers play in the health and care breakthroughs that research can create. Sign up to explore studies near you: https://t.co/DaLo6mmGhv
#BePartOfResearch #CTD2025
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International Clinical Trials Day celebrates the importance and impact of clinical research — from prevention to cure. The UKCRC Registered CTU Network is proud of the work our members do to save and improves lives. #ICTD2025 #ClinicalTrials #HealthResearch #UKCRC #CTD2025
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In clinical trials it is not only potential benefits that should be measured - it is crucially important that any potential #harms are also investigated 1/7 #MethodologyMonday #118
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