Singleron_Bio
@Singleron_Bio
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We develop and commercialize cutting-edge single cell multi-omics solutions. From tissue processing, single cell library prep, to data analysis and insights.
Connecticut and Michigan, US
Joined March 2021
A packed room at Hongkong University when @RongFan8 , Singleron co-founder, gave a seminar today. Novel #technologies are attractive! .#singlecell #Innovation #spatial #multiomics
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How to # QC #singlecell or nuclei for #singlecell #sequencing experiments? Hear what @Singleron_Bio scientist says!
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Power of #singlecell #multiomics.
Scientists show that paired analysis of #CD69 mRNA and protein levels can help identify potent CD8 T cells with enhanced #cytotoxic effector functions within exhausted populations in tumors. @RayArja @MaxKrummel. Learn more in Science #Immunology:
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Not too harsh, but not too gentle either: learn more about our #tissue #dissociation solutions, both manual and automated, that helps you to get happy viable #cells from any tissue type!.Find out more on our homepage:.
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Harsh enough to #dissociate #tissues, gentle enough to keep #cells happy. The perfect balance! Find out more about our tissue dissociation solutions:
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Abu Dhabi moves fast in #precisionmedicine, and Singleron is becoming an active member by forming AD-Omics, a joint venture with IHLAD.
Precision medicine is evolving in Abu Dhabi. At #ADGHW2025, Nan Fang of Singleron & IHLAD announced a joint venture to bring single-cell multi-omics tech to the region, accelerating cutting-edge research & innovation. Register for 2026:
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#organoid engineered for #bone #repair: #singlecell #RNAseq using Singleron products identified #stemcell network behind it.
nature.com
Nature Communications - Critical-sized bone defects are a clinical challenge, with long-term recovery often leading to delayed union or nonunion. Here, Zhang et al. report an engineered...
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This paper just coming out today in @TheLancet #Haematology outlines how #digitaltwin enables #personalized #CAR-T therapy. By CERTAINTY, a #EU -sponsored consortium where Singleron is a proud member.
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Virtual twins for #personalised #CAR T-cell therapy in #myeloma - The Lancet #Haematology : proud to be part of the CERTAINTY Consortium that is developing this #virtualtwin!
thelancet.com
Multiple myeloma is a haematological malignancy characterised by the clonal proliferation of plasma cells in the bone marrow. Despite advances in treatment, multiple myeloma remains incurable, with...
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#Adipocyte -specific #Zeb1 downregulation remodels the tumor-associated #adipose #microenvironment to facilitate female breast #cancer progression: Singleron GEXSCOPE Single Nucleus RNA Library Kit used. #singlecell #transcriptome
nature.com
Nature Communications - Breast cancer cells interact with cancer-associated adipocytes in the microenvironment. Here, the authors report that the cross-talk between these two cell types is...
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just published in @SciImmunology , researchers found #Riplet to be related to resistance to #immunotherapy. #singlecell #RNAseq using @Singleron_Bio kit was used to obtain a comprehensive and unbiased picture on how Riplet affects #TME.
science.org
Riplet promotes CD8 T cell exhaustion and anti–PD-1 resistance in HCC.
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RT @humancellatlas: We’re excited to start the 2025 HCA General Meeting today. Looking forward to many insightful discussions and collabora….
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Label-Free #singlecell #sequencing #Multiplexing Using SNP Genotyping: Bioinformatics Techniques: a Singleron webinar
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CellFM: #singlecell Foundation Model by Singleron and collaborators, outperforming existing models in cell annotation, perturbation prediction, gene function prediction, and gene-gene relationship capturing.
nature.com
Nature Communications - Single-cell sequencing reveals cellular heterogeneity but is challenged by technical noise and batch effects. Here, authors present CellFM, an 800-million-parameter...
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Singleron’s #singlecell product was used in this intriguing study to reveal #transcriptome profiles in #ILC3s.
#Helminth infections reprogram group 3 innate lymphoid cells (#ILC3s) to boost #ILC2 responses and enhance type 2 immunity, according to new research from @Tsinghua_Uni. Read more in Science #Immunology:
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Meet us at Human Cell Atlas General Meeting 2025 in Singapore!#singlecell #cellatlas @humancellatlas
singleron.bio
Meet us at the Human Cell Atlas General Meeting 2025 in Singapore from 9-11 June, 2025. Stay up to date with the latest news from Singleron Biotechnologies.
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#Oncogenic fusions converge on shared mechanisms in initiating #astroblastoma: Singleron #singlecell products used.
nature.com
Nature - The molecular mechanisms of astroblastoma development are identified, whereby distinct gene fusions upregulate shared transcriptional networks to disrupt the normal development of ventral...
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RT @Singleron_Bio: Want to know why and how we developed Tensor, our #highthroughput#singlecell processor that will automate steps from cel….
us06web.zoom.us
Zoom is the leader in modern enterprise video communications, with an easy, reliable cloud platform for video and audio conferencing, chat, and webinars across mobile, desktop, and room systems. Zoom...
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