I'll be speaking at 2025 International Forum on Research Excellence on Oct 18 - Nov 01, 2025. I would love to see you there!🎉🎉 Register here: https://t.co/OiLid4bmFm #IFoRE25 - via #Whova Event Platform

These findings suggest potential therapeutic strategies aimed at enhancing regulatory T cells, and identify a target for antigen-specific T cells that may enable precision therapeutics in ALS.

It’s giving minimum effort, maximum vacation vibes.

We identify the C9orf72 protein as a target for a T cell inflammatory autoimmune response with IL-5/ IL-10 releasing CD4+ T cells that might have an anti-inflammatory role.  IL-10-mediated T cell responses were significantly higher in donors with a longer predicted survival time

It was suspected that autoimmune responses may play a role in ALS pathology, and that T cells contribute to the rapid loss of neurons during progression of this devastating disease, with little recourse for the involved patients.

I am excited to share that our new study on Amyotrophic lateral sclerosis (ALS) is out in Nature today. Awesome collaboration with Dave Sulzer at Columbia and several clinical groups; and a big thank to all blood donors.

APOL1 Genetic Testing at No Cost to Patients! Are you incorporating APOL1 genetic testing into your workflow? Discover No-Cost APOL1 Genotyping Program for eligible patients sponsored by Vertex Pharmaceuticals. Learn more today!

The emphasis on communication is most important, and we all as Scientists have the crucial task to communicate scientific results to scientists in their disciplines, but also to non-scientists and the general population.

The Prize was instituted in 1950 to honor contributions to Science , with emphasis on communicating research to scientists in other disciplines. It is humbling to see that previous recipients involved four Nobel Prize winners, and Jane Goodall, Margaret Mead and Stephen Jay Gould

Honored to receive the 2025 Procter Prize for Scientific Achievement "for understanding basic mechanisms of antigen recognition and immunity, predicting immune activity, and developing interventions against cancer, infection, autoimmunity, and allergies. "

I am honored to have received the 2025 William Procter Prize for Scientific Achievement "for understanding basic mechanisms of antigen recognition and immunity, predicting immune activity, and developing interventions against cancer, infection, autoimmunity, and allergies. "

Prestigious prize recognizes Sette's accomplishments as a researcher and scientific communicator

https://t.co/rf9o5zpuOt

Encouraging all qualified candidates to apply for the ISSNAF prizes. A wonderful opportunity to get recognition and network with your peers.If not directly eligible, please circulate to your peers.

Futures Traders: Now you can get 30% off for life, never pay an activation fee, and get 100% initial test refunds with your first withdrawal! Use code NOFEE100 to claim this limited time offer.

Particularly significant to be awarded on the 2025 Italian Research day. I am proud to follow my passion for Research. Scientific research has a profound impact on technological breakthroughs, human health, economic growth and education, and should not be taken for granted.

I am honored and humbled to have been knighted by the Republic of Italy as Cavaliere al Merito della Repubblica. Heartfelt thanks to the Italian Government, Italian Embassy, the Consul Raffaella Valentini, ISSNAF , my family, friends and colleagues.

Have you registered for the 2024 IEDB Virtual User Workshop yet? It will be held from November 5 to 7 on Zoom, so it's totally free. Sign up now! https://t.co/Szr5gz0WDY More information can be found here - https://t.co/N07ZjKCUKN We look forward to seeing you on Zoom, soon!

https://t.co/V5SitJzk4w

We conclude that should a widespread human HPAI H5N1 outbreak occur, cross-reactive T cells might limit disease severity.

We found most previously identified CD4 and CD8 T cell epitopes are identical or highly conserved. Our experimental data shows a nearly complete preservation of pre-existing T cell responses in HPAI H5N1 recognition

Is there some degree of H5N1 preexisting immunity in humans? Cross-reactive H5 antibodies are low or not detected. However, the N1 component is shared between seasonal H1N1 and H5N1 What about T cells? Our study fills in this gap-of-knowledge

Recent cases of H5N1 2.3.4.4b flu from poultry and mammals into humans raised potential pandemic concerns. And a Recent report on H5 human case in Missouri increased the concern on potential human to human transmission: https://t.co/yKjxeL06oo.