Translational Immunology
@Salihlab
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Developing next generation immunotherapeutics until the stage of clinical evaluation; Research on host tumor interaction; novel antibodies and peptide vaccines
Tübingen, Germany
Joined October 2021
PhD position in Immunology of #Endometriosis at Uni Hospital Tübingen! Join the ENDO-RELIEF project (65%, 3 years, with extension option). Apply by 25.11.2024. More info: https://t.co/yx18vNLx2Y
#PhDPosition #Immunology #Endometriosis #ResearchJobs #jobalert #hiring
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Our wakeboarding trip couldn’t happen this year, but the team still had a great time. Thanks to Jonas and Melly for organizing! #teamspirit #bbq
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Announcing August Lab #TourDeForce Champs: - Martina Lutz: 🎽🟡Bispecific checkpoint inhibitors - Jonas Mauermann: 🎽🟢 Lightning-fast cytotoxicity assays - Nisha Prakash: 🎽⚪️🔴 Tetramer staining success - @KlimovichBoris: 🎽🦅 Superagonistic T cell engagers
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🎉Celebrating our annual White Party together with @LabWalz.🎉 Proud to announce the ennoblement of Lady Juliane and Lord Helmut of the Glen! #Tuebingen
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Glad to announce our ACE2-M fusion protein, effective against SARS-CoV-2 escape variants, won the #Science2Start award! Congrats Dr. Latifa Zekri and team! #BioRegioSTERN
https://t.co/JpRv1nxl9s
bioregio-stern.de
(Stuttgart/Tübingen) – Der Sommerempfang der BioRegio STERN Management GmbH bot auch in diesem Jahr den festlichen Rahmen für die Science2Start-Preisverleihung.
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Now online - check out this video from @StrubeStiftung where @JulianeWalz introduces our new phase I #ClinicalTrial for an #immunopeptidomics-based #peptide #vaccine for #patients with #AML. https://t.co/dkHnMz6dew
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✨Thrilled to share our new paper on Novel B7-H3 #CD276 #antibody in #AML published in @Cancers_MDPI! Congrats to our #PhD student @S_Stefanczyk, @Lsfm3DNSCsClara and the team led by Melanie Märklin @MMaerklin! @MDPIOpenAccess @CoE_iFIT
https://t.co/iC0N4AtkQL
mdpi.com
Despite recent advances in immunophenotyping, the prognosis of acute myeloid leukemia (AML) is still mainly estimated using age and genetic markers. As the genetic heterogeneity of AML patients is...
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The Lab #TourDeForce June champs: - Polina Kaidun 🟡🎽 for novel #Tcell constructs - Britta Statz 🟢🎽for screening of #bispecific costimulators - Martina Lutz ⚪️🔴🎽 for target restricted checkpoint inhibitors - Nisha Prakash Eddie the 🦅🎽 for perseverance despite no new data
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We are starting a phase-I #clinicaltrial for our #peptide #vaccine against acute myeloid leukemia (AML). We are looking for #AML #patients after first-line therapy and aim to avoid relapse due to minimal residual disease. For more information, check out: https://t.co/8ej98vFrB6
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An optimized IgG-based B7-H3xCD3 bispecific antibody for treatment of gastrointestinal cancers. A study by @Salihlab & others in @MolTherapy #ASCO24
cell.com
Presently available bispecific antibodies for cancer immunotherapy constructs cause substantial cytokine release resulting in dose-limiting side effects and lack sufficient potential to stimulate...
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Happy and proud to be part of the ENDO-RELIEF project in collaboration with @MMaerklin from @Salihlab supported by the @BMBF_Bund aiming to better understand the development of #endometriosis. https://t.co/84DC5V7Gla
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🏆 May Lab #TourDeForce Heroes! 🎉 🟡🎽Tatjana Schreiber leads with precision in mentoring 🟢🎽Emma Nill excels in #bispecific constructs cloning ⚪️🔴🎽Nisha Prakash masters experimental optimization of #Tcells Polina Kaidun bravely tackles hurdles with the Eddie the 🦅🎽 spirit!
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💫 Exciting news! Our B7H3xCD3 #bispecific #antibody CC-3 shows promise in fighting bone & soft tissue sarcomas. Congrats to Samuel Holzmayer & team! @MMaerklin @CoE_iFIT #immunotherapy ➡️ https://t.co/MGPT9YDAF2
frontiersin.org
Sarcomas are rare and heterogeneous malignancies that are difficult to treat. Approximately 50% of patients diagnosed with sarcoma develop metastatic disease...
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🏆 April Lab #TourDeForce Champs! 🎉 -@KlimovichBoris 🟡🎽 pioneering anticancer breakthroughs -Polina Kaidun races in 🟢🎽 for innovation -Nisha Prakash ⚪️🔴🎽conquers experimental frontiers -Emma Nill 🦅🎽tackles cell culture hurdles with Eddie the Eagle spirit!
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Excited to share our latest study "Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody" in @BloodCancerJnl. Congrats to @S_Stefanczyk @MMaerklin and all contributors! 🎉 #AML #Leukemia #immunotherapy #ADCC
https://t.co/j1FRCwh8CE
nature.com
Blood Cancer Journal - Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody
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