Saba Shaikh
@SabaShaikhMD
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Another option for patients in clinic! Nice way to welcome Breast Cancer Awareness month. Now hoping we can also get approval for Imlunestrant plus abemaciclib- statistically significant and clinically meaningful activity seen regardless of ESR1m @MSKCancerCenter @MSK_DeptOfMed
The FDA has approved imlunestrant (Inluriyo) as therapy for pretreated ER+, HER2-, ESR1-mutated advanced or metastatic breast cancer. https://t.co/2sS0H4g3iD
#bcsm #oncology | @FDAOncology | @jhaveri_komal
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Robust benefit of SG+pembro in first line tnbc. Still don’t know what to do post kn522 since very few such patients included but this should be a new soc. @stolaney1 #ASCO2025
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Grateful for this opportunity and committed to improve diversity in clinical trials @eaonc
Congratulations to the Spring 2025 recipients of the Edith Peterson Mitchell, MD #HealthEquity Travel Scholarship! #EAOnc 🩺
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How are results from DB11 going to change early breast cancer treatment?
New #SABCSSnippets: Saba Shaikh and Shanu Modi discuss results of the Phase III DESTINY-Breast11 trial, which show the promise of Enhertu as an alternative to anthracycline-based regimens for high-risk, locally advanced HER2+ breast cancer patients: https://t.co/irA4Lr9TEu
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Thank you Dr Modi for joining us for a great discussion! Excited to see the data soon!
New #SABCSSnippets: Saba Shaikh and Shanu Modi discuss results of the Phase III DESTINY-Breast11 trial, which show the promise of Enhertu as an alternative to anthracycline-based regimens for high-risk, locally advanced HER2+ breast cancer patients: https://t.co/irA4Lr9TEu
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Otto Metzger (@Otto_DFCI) presents the practice-changing results from the #PATINA phase 3 trial: adding palbociclib to maintenance ET after 1L THP for HR+/HER2+ MBC significantly and meaningfully improved PFS (44 vs 29 months, HR 0.74, p=0.007). 44 months!!!!!!!!!!!!!!!!!!!!!!!!
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Speaking of ways to make sure EVERYONE has access to learning at #SABCS24, things I noticed: 1️⃣ sign language interpreter 2️⃣ child care on site (I peeked in, they were multiple kids having fun) 3️⃣ multiple mothers rooms for pumping 4️⃣ prayer rooms #SABCS24
@SABCSSanAntonio
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Significant OS benefit of pembro. Now questions are: do we need that much chemo; do we need adj pembro after pCR; is there signature of response; what do we do with T1c? Great discussion below. @SABCSSanAntonio @stolaney1 @KateIdaLathrop #sabcssnippets
.@stolaney1 and #SABCS24 program director @KateIdaLathrop discussed the phase III KEYNOTE-522 trial, which recently met its overall survival endpoints in patients with high-risk early-stage TNBC. Watch now on #SABCSSnippets: https://t.co/NqdrVIw0T2
@UTHealthSAMDA
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A wonderful collaborative effort with 4 institutions @LubnaChaudhary1 @YAbdouMD @SabaShaikhMD @royaryam Real world outcome data with sacituzumab govitecan in metastatic breast cancer.
Great to have multi institution collaboration with clinically driven hem onc fellows @DrNH590 @royaryam @MCWCancerCenter @Froedtert @RoswellPark P03-06-10: Real world outcomes with Saci in mTNBC. @gandhi_shipra #breastcancer #clinicaltrials #sabcs23
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In the middle of a discombobulated week, a multiple bad scans-kind of a day, a running 2 hours behind day, there’s a person that just wants to tell you how grateful they are to be alive, for the team’s care of them over the years. Suddenly time stops. And that’s oncology folks 🙏
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We can finally complete the table with all results (PFS and OS) from the CDK4/6 inhibitors phase III trials in HR+/HER2- MBC 👇🏽 OS in Paloma-2 was the only outcome did not meet significant difference 🪄🤨
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An important study by @EMittendorfMD Of those with clinical node- TNBC ~10% of T1ab tumors, + ~15% of T1c tumors will be node + at surgery. Important implications for who needs preop tx + pembro. Consider axillary US in these pts @OncoAlert
pubmed.ncbi.nlm.nih.gov
Pathologic node-positive disease is found in > 10 and 20% patients with cT1cN0 and cT2N0 TNBC, respectively. Axillary ultrasound can be used to identify patients presenting with a normal clinical...
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Group photo of the home crew from Fox Chase 📸@FoxChaseCancer @TempleHealth at #vailworkshop #MCCR22 @ASCO @AACR with @BenMironMD @JJuddOnc Saba Shaikh and Cyrus Mazidi - snapped at a rare moment when we were not hard at work on protocols! Photo credit @ronanhsieh
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Congratulations to our amazing @PittHemeOnc class of 2022! So incredibly proud of all of you @KarapetLilit @MaxJLee @SabaShaikhMD @UPMCHillmanCC
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