One of our lab assistants made me melanoma cookies as a parting goodbye. I was touched.

If a sentinel node is negative on a pT2a or greater melanoma, what is the likelihood of having positivity if an added 2 deeper (level) tissue sections and IHC were evaluated. I would venture it is greater than 5% depending on various factors. If so, why aren't we doing that?.

Anyone know of a lab that performs IHC for Monkey pox?.

Melanoma cytology

Is there such a thing as a pelvic lipoma. Urologist use this term when performing prostatectomies. That is, right and left pelvic lipomas. Sounds suspicious that they are just making up that clinical diagnosis to clear away fat to remove lymph nodes? Thoughts?.

Good upcoming article in J Cutan Pathology.

Requirements which should be removed in the reporting of melanoma .1. Clark level .2. Tumor infiltrating lymphocytes.3. Regression .Radial/vertical growth phase (not a req) but some mention it. Present/absent solar elastosis (not a req), but some mention it. Agree/disagree?.

There are several different manifestation of psoriasis. Is psoriasis one dz or multiple diseases? That is, will there ever be a time when we combine the clinical with histology with molecular/proteinomic info. That is, you have psoriasis, type 1 or psoriasis type 2, etc.

Thoughts on this finding within the myometrium. What IHC stain/s would you order?

In benign pelvic fluid specimens that are cellular in which you can't tell if the cells are mesothelial cells or histiocytes, or a combination of the two, what is the most appropriate cytologic diagnosis?.

A few more pics.

Solitary lesion on the knee in an adult. Your diagnosis is: A) Hidradenocarcinoma .B) Primary cutaneous cribriform carcinoma/tumor .C) Primary cutaneous apocrine carcinoma .D) Metastatic carcinoma .E) Benign adnexal/sweat gland tumor

Just a pretty picture

Is there anyone other than Mayo clinic who does mass spectroscopy for amyloid? Commercial testing.

A blob of dystrophic calcification within a nevus. If Nanta can do it with bone, I think I do it with this calcification. I will call it Nevus of Kolker

Pretty cool pic of nevus cells surrounding a pool of mucin and forming a animal-like silhouette

I thought this was a fairly good example of lichen planopilaris.

If a melanoma is widely excised, do you .1) simply state widely excised.2) give the exact distances from the peripheral and deep margins .3) pick an arbitrary "greater than" number, such as greater 5 mm from peripheral and deep margins.

HMB45 stain. For this melanoma met to a sentinel node, how would you measure the size of the metastatic deposit: Blue line, black line, or red line. Is the location both subcapsular and intraparenchymal, or just subcapsular.