The Weinberg Lab
@SHWeinbergLab
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Computational Physiology Lab. We develop computer models of molecular, cellular, and tissue physiology.
Columbus, OH
Joined October 2018
RT @OSUengineering: External funding for research in The Ohio State University College of Engineering is showing no signs of slowing down. ….
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RT @drmichaellevin: Check out a very cool talk given at our Center today:. ."Calcium homeostatic feedback….
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RT @NSF: NSF is awarding CyberCorps Scholarship for Service grants to 4 academic institutions with an investment of nearly $15M toward trai….
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RT @ajpheartcirc: New study provides valuable insights into age-dependent changes in human cardiac gene expression & #electrophysiology, sh….
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RT @CMBEjournal: Hirway et al. developed a multicellular computation model to investigate tumor microenvironment remodeling and pre-metasta….
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Great thread from @moise_nick on his recent work modeling atrial fibrillation. "AF begets AF" - Nick developed a framework to model this progression from healthy to disease tissue, coupling the electrical activity and substrate remodeling, a complex multi-time scale problem!.
Glad to get this preprint out, with @SHWeinbergLab. In atrial fibrillation, chaotic activity directly drives substrate remodeling, which then influences the activity itself. But how does this process evolve long-term, as a coupled dynamical system? 1/13.
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which informed model predictions of key currents underlying the age-progression of action potential and calcium transient characteristics. There's a whole lot more to do, and I'm exciting to see where the project will go next.
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We were fortunate to find the perfect collaborator in the Posnack lab at just the right time. Fast-forward to now, and this project has led to an invaluable analysis (and data set) of cardiac gene expression throughout development (> 100 patients, age 5 days to adulthood), . .
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For my group, this project started years ago with the seemingly simple question of – how do we model cardiac electric activity in pediatric heart cells? Which led us to the even more fundamental question of – what do we even know about pediatric heart electric activity?.
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Really proud to share this latest work just published in @ajpheartcirc, led by Shatha Salameh, @DevonGuerrelli in the @NikkiPosnack lab and Jacob Miller in my lab.
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RT @DeanBradfordMD: Congratulations to 3 teams from @ohiostatemed & @osuengineering receiving funding from the Center for Medical and Engin….
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RT @ChEnected: Umit Ozkan of @OhioState is the 2024 recipient of AIChE's Margaret H. Rousseau Award in recognition of her work bridging het….
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RT @OhioStateNews: $26M in federal funding announced today will support creation of an @NSF Engineering Research Center at @OhioState to ju….
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RT @OSUengineering: In the new Pelotonia Research Center, engineers collaborate with biologists, physicians, data scientists and others to….
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RT @MorottiLab: 📢 Postdoc alert!!!. Hey Twitter community, .we are excited to announce two postdoctoral positions available in computationa….
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RT @OhioStateERIK: In Ohio State’s Pelotonia Research Center, Ohio State engineers collaborate with biologists, physicians, data scientists….
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RT @KITP_UCSB: New KITP Program! #CARDIO26.Multi-Scale Physics of Normal and Diseased Heart: from Ion Channels to Whole Organ . Dates: 3/30….
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RT @OhioStateBME: Congrats to Seth Weinberg for being named a Fellow of the @American_Heart Association for his research and contributions….
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RT @JACCJournals: Dravet syndrome, a congenital epileptic disorder is assoc w/ high risk of SUDEP. This involves the remodeling of NaV 1.6….
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RT @OSUengineering: Read about our 2 newest NAE members, the @OhioState Innovator of the Year, 6 members of the Class of 2024 & more in the….
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