The Rotello Group
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Hurray!!.Congratulations to Prof. Vincent Rotello for being recognized in s 2024 list of top scientists as 99th in the U.S and 223rd in the world among the Best Materials Science Scientists.
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Congratulations to Prof. Vincent Rotello for being ranked 220 in the world and 115 in United States by .
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Congratulatons to Prof. Vince Rotello for being placed as the top 0.05% of all scholars worldwide by ScholarGPS.
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Liang Liu and colleagues developed a responsive bio-orthogonal catalysis system utilizing an enhanced green fluorescent protein (EGFP)–nanozyme (NZ) composite (EGFP-NZ).
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In this research, Zhai et al. uncovers a new molecular process that may utilize ROS-Nrf2-p62 signaling to regulate macrophage Mox polarization. This discovery offers potential for enhancing the safety and effectiveness of nanomaterial usage.
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In this article, Zhang et al. reports gold nanoparticle based bioorthogonal nanozyme for repolarizing macrophages from M2-like to M1-like phenotype providing a potential strategy for anticancer immunotherapy.
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Congratulations William the 2024 RCSA fellowship.
Eight postdoctoral scholars have been selected to participate in the first year of the #RCSAFellows initiative, which aims to help increase faculty diversity in the physical sciences through job search preparation and community building.
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Nabawy and colleagues describe the creation all-natural antifungal treatment by gelatin-based nanoemulsion platform integrated with a natural essential oil with antimicrobial properties, aimed at treating biofilm associated fungal infections.
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Hirschbiegel et al. reflect upon the impact of our inaugural work on nanoparticle hydrophobicity and protein corona formation on the scientific community in this Materials Horizons 10th anniversary special. Check it out!.
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In this article, Hirschbiegel (@cm_hirschbiegel) & Goswami et al. showed how modulating the hydrophobicity of the polymer scaffold can enhance catalyst loading efficacy, catalytic activity, and serum stability of bioorthogonal polyzymes. Read more:
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In this review, Goswami and Gupta et al. discuss the importance of nuclear targeting and how the interplay between nuclear import pathways and nuclear localization signal (NLS) motifs can help pave the way for better therapeutic design and delivery.
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In this article, Profs. Epple, Rotello and Dawson discuss the opportunities and challenges of ultrasmall nanoparticles. Read more:.
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Thrilled to see this work highlighted in Materials Horizons 10th anniversary regional spotlight collection: The Americas !.@MaterHoriz.
Intracellular bacterial infections are difficult to treat. In this study, Hardie, Makabenta et al. leveraged bioorthogonal catalysis to generate antibiotics within host macrophages (in situ) to fight intracellular infections. Read more here:.
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In this study, Huang & Fedeli et al. examine the effects of ligand headgroups on the dynamics of organic ligands attached to gold nanoparticles. Read more:.
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In this work, Makabenta et al. stabilize and deliver non-antibiotic antimicrobial phytochemicals using polymer-stabilized biodegradable nanoemulsions, achieving high bacterial clearance (99% bacteria reduction) in a MRSA-induced murine model of peritonitis
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In this review, Keum & Hirschbiegel et al. discuss current strategies for intracellular catalysis and applications of biomimetic and bioorthogonal nanozymes. Check it out!.
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In this work, Makabenta & Nabawy et al. tackled difficult-to-treat wound biofilm infections by integrating antimicrobial polymeric nanoparticles into hydrogels, clearing 99% of bacterial infection and significantly enhancing wound healing in vivo.
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In this work, Nabawy & Gupta et al. demonstrate the design and application of a biodegradable nanoemulsion that encapsulates a palladium-based TMC, generating bioorthogonal nanocatalysts for anti-cancer applications.
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In this article, Park et al. in collaboration with the @VachetLab, report a combination therapy for biofilm infections. Silver nanoclusters and eugenol integrated into polymeric biodegradable nanoemulsions demonstrated synergistic antimicrobial activity.
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