👶Improving IVF success remains a huge challenge in reproductive medicine. This new multicenter randomised clinical trial by Urmila Diwekar et al. introduces and evaluates a novel decision support tool aimed at helping clinicians optimise IVF outcomes. 🔗

Could AI and automation help make fertility treatments more affordable in low- and middle-income countries? .A new review by Gerardo Mendizabal-Ruiz et al. explores how these technologies could streamline ART and open doors to inclusive care. 🔗Read here:

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Optimising livestock pregnancy outcomes starts with understanding the uterus and placenta at the biochemical level. This latest review by Katherine Halloran and Claire Stenhouse examines the metabolic pathways that regulate their development and function.

Reproduction and Fertility is heading to SSR 2025 in Washington D.C.! 🇺🇸. Visit our booth to learn about publishing with us, chat with the team, and explore our latest Special Collections. We’re there to answer all your questions - see you there!

📢 We’re recruiting Early Career Associate Editors for Reproduction and Fertility! . Open to basic, non-clinical scientists and also for clinicians-in-training or embryologists working in the area of clinical reproduction and fertility. For more info:

Which method leads to better outcomes in #FrozenEmbryoTransfer (FET) - natural or artificial cycle?. New research by Romana Dmitrovic et al. suggests natural cycle FET may offer higher live birth rates, though other factors also play a role. 🔗

🌟New review in our Fertility Care in LMICs special collection!.Why do many patients in South Africa abandon fertility treatment?.Gerhardus Boshoff, Willem Ombelet and Carin Huyser present a public-sector case study uncovering systemic access barriers. 🔗

🌟We are proud to announce that Reproduction and Fertility's 2024 Impact Factor has risen to 3.4!.This increase reflects the growing recognition of the high-quality research published in the journal - thank you to our authors, reviewers, and editors for making this possible.

Where should we host our next #RaFJC Journal Club?. 📢Vote and share your thoughts!.

🎉 That’s a wrap on this #RaFJC journal club!.Huge thanks to everyone who read, shared, voted, and engaged in debate. 📌 Missed something? Catch up via #RaFJC.🔜 Stay tuned for our next journal club - coming soon!. #Microbiome #Piglet

💬 What insight from today's #RaFJC are you taking into your work?.🟣 Drop your takeaways.🟢 Ask a question.🟡 Share your next steps.🔁 Let's keep this thread going!. #Microbiome #Piglet.

🧠 The study opens up some exciting possibilities for enhancing #Piglet health!.Which of these strategies would you prioritise?👇.🔘 Modulate sow vaginal flora.🔘 Enrich colostrum with probiotics.🔘 Re-seed piglets after day 3.🔘 Improve crate hygiene. #RaFJC #Microbiome.

Other suggestions?.🔁 D10 resembles D0.💪 Maternal imprinting is resilient.🧠 The idea of a "core microbiome" taking shape by day 10 is intriguing for intervention planning.The main conclusion? .Despite the chaos on D3, #Piglets' #Microbiomes "reset". #RaFJC

🙌 This study challenges assumptions about early-life seeding.💥 Crate disinfection and clean environments? It had no significant impact on gut microbiota colonisation.🧪 It's not where they are born, but how and from whom. #RaFJC #Microbiome #Piglet

Key findings.🧬 The #Birthcanal #Microbiome –rich in #Lactobacillus– seeded the #Piglet gastrointestinal tract. 👍 Could be used as a mirror of human vaginal delivery.❌ Colostrum had little impact. 💡 Could interventions in the dam's vaginal flora boost offspring health?.#RaFJC

🧬 Working on similar models or study designs? Share your insights - check out the options and join the conversation! 🐷💬. 🔘 Birth canal.🔘 Colostrum.🔘 Farrowing crate.🔘 Environmental contamination. #RaFJC #Piglet.

By weaning (day 21), the #Piglet #Microbiome is more predictable. ➡️ The day 10 profile explains almost 60% of the variation. ❌ Environmental factors (crate, colostrum) contribute little. Microbial "memory" builds postnatally. #RaFJC .📊 See the results in Table 5!

Despite the microbial chaos on day 3, the #Piglet #Microbiome begins stabilizing by day 10. 🔁 The day 0 microbiome still explains 15.6% of the variation at day 10.🌸 #BirthCanal still matters: 6.5% of the variation. #RaFJC .📊 See the results in Table 4!

Day 3 = #Microbiome mayhem. 🦠 Low diversity.🧬 Dominated by Escherichia & Clostridium.🩺 Markers of dysbiosis, but #Piglets weren’t sick.This window may be key for intervention or risk. #RaFJC.📊 Check Figure 2 to see the relative abundance of genera

The #Piglet #Microbiome shifts drastically by day 3:.🔺Proteobacteria dominate.🔻Beneficial genera like #Lactobacillus & Ruminococcus drop.🔺Escherichia spikes (38%).🦠 Early instability is real and measurable. #RaFJC .📊 See Figure 1 to see the relative abundance at each stage!