Deborah Perlstein
@Prof_Perlstein
Followers
121
Following
145
Media
23
Statuses
131
metalloenzyme enthusiast|Educator & Mentor making the world a smarter and kinder place|Lover of (Red Sox) baseball, ballet, Berkshires, beagles & boston
Boston, MA
Joined March 2022
I have been learning about machine learning. If you want to learn with me, see our article! Many thanks to all the trainees who wrote and edited this mammoth of a book chapter and the reviewers for their effort! .
currentprotocols.onlinelibrary.wiley.com
Machine learning (ML) is rapidly gaining traction in many areas of experimental molecular science for elucidating relationships and patterns in large or complex data sets. Historically, ML was...
0
0
0
3) we find some of the first, direct biochemical evidence for role of the CIOA3/Nar1 protein in cluster trafficking. I hope you enjoy the paper! we are very excited to have this out there, if only in preprint form for now.
0
0
1
2) we determine that a disease causing mutation in Cia1 results in disruption of the Cia1-Cia2 complex, and as a result, client recruitment and maturation.
1
0
1
1) the Cia2a paralog of Cia2 found in animals is possibly not a specific assembly factor for IRP1 but likely binds to and facilitates maturation of additional clients.
1
0
1
It was a surprise to us that the Cia2 subunit of the targeting complex makes key interactions, as the current working model of CTC function delegates Cia2 to a Fe-S binding module. This discovery has 3 major implications for understanding this complex system.
1
0
1
In this paper, we determine that the Targeting Complex Recognition (TCR) motif recently identified through a collaboration with my lab and @AJPierik's lab binds at the interface of Cia1-Cia2 complex in the cytosolic iron-sulfur cluster targeting complex (CTC).
1
0
0
I had to recover my X login to share our preprint! Watch this space - exciting other papers to soon follow!.we have been working very hard to "crack the CIA code".
biorxiv.org
The cytosolic iron-sulfur cluster assembly (CIA) targeting complex is responsible for maturation of cytosolic and nuclear iron-sulfur enzymes, numbering >30 proteins critical for fundamental proces...
1
0
0
RT @AJPierik: Anastasiya Buzuk and colleagues from the Perlstein lab (@Prof_Perlstein) provide insight into Nar1 trafficking, CIAO2A functi….
biorxiv.org
The cytosolic iron-sulfur cluster assembly (CIA) targeting complex is responsible for maturation of cytosolic and nuclear iron-sulfur enzymes, numbering >30 proteins critical for fundamental proces...
0
1
0
Following the X-its - find me @perlstein.bsky.social. Like I have so much extra time to build a new social media. Help me out and help me find you there!.
0
0
0
Want to work with me or one of my amazing colleagues? Attend open house for @BUChemistry tomorrow!.now I am off to work on the single slide that represents my group which is orders of magnitude harder than making 10!.
Interested in completing a Masters or PhD in Chemistry? Attend our virtual admissions information session on November 13! Register at the link below:
0
0
0
Watch out @ericscueny @minjung_son @Chem_Diva - the fire department inspector is on site .it will be a ruff day @BUChemistry
3
0
5
Congratulations to Anastasiya on receiving Pfizer Emergent Leader Award! The Perlstein lab and your former PI are so proud of you!
acswcc.org
Pfizer Emergent Leader Award The WCC Pfizer Emergent Leader Award recognizes up to eight outstanding individuals in the second year and above of their graduate studies or undertaking post-doctoral...
0
0
5
Loved seeing all the chemistry at the undergraduate poster session! @derosalab @porco_lab @BUChemistry @minjung_son
1
1
5
RT @BUChemistry: Interested in completing a Masters or PhD in Chemistry? Attend our virtual admissions information session on November 13!….
0
3
0
Aaahhh - and my undergrad mark wins NESACS travel award! Amazing work y’all. Your PI could not be more proud!.
0
0
2
Congratulations to recent Perlstein Lab PhD student Anastasiya Buzuk on her award of the Pfizer Emergent Leader Award from @AcsWcc! I could not be more proud of you!.
1
0
8
RT @DerbyLabDuke: 🚨@DukeChemistry is hiring! We invite applications for two tenure-track positions at the Assistant Professor level to cand….
chem.duke.edu
The Department invites applications and nominations for two tenure-track positions at the assistant professor level to begin July 1, 2025. In both positions we are seeking colleagues with strong...
0
30
0
Yes! Jackson wins a poster award at the FeS meeting!!! So proud and well deserved!
0
0
14
Congratulations Anastasiya! Your talk today to earn your PhD was amazing!
0
1
12