Simon Waddington
@ProfSimonWad
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Professor of Gene Therapy, University College London 🧬🚲🛠
London, England
Joined August 2011
Now live - our review of neurodegeneration in lysosomal storage disease - comparing and contrasting disease mechanisms; emerging evidence of unifying convergence https://t.co/ln5ZAtlbZ8
onlinelibrary.wiley.com
There are currently at least 70 characterised lysosomal storage diseases (LSD) resultant from inherited single-gene defects. Of these, at least 30 present with central nervous system (CNS) neurodeg...
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Keeping with the new principles of this place where positivity is rewarded: there is a lovely microblogging site hosting my 6th in a series of superwomen in the history of genetics. Rosalind Franklin - prodigious talent https://t.co/AX5oy5nNXO
@_BSGCT
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The 6th in a mini-series of posts about the history of women contributing to genetics - some being recognised, others not so much... https://t.co/2z3md4QLT0
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Check out our translational research to develop a gene therapy for a childhood mitochondrial disease (@Mito_Therapy @Dr_RKarda)
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Please apply 👇🏼
We are looking to appoint a Research Technician to join Professor @MariyaMoosajee's lab, investigating the development of non-viral approaches, using mRNA and non-viral gene therapy, as potential treatment options for RLBP1-retinopathy. Closes 27 Nov:
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Non-biology photo here. This is the Britannia Hotel in Manchester £50/night- (lecturing at Manchester Metropolitan). Manchester is a beautiful place. @DrNLK0 @drol007 @helencooksley
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Check out our work at #ESGCT2024 : •My poster #P0479 on our patented viral vector GT for metabolic diseases •Ala'a Siam #OR043 •Luke Tappouni #P0510 •Sam Devereaux #P0745
https://t.co/qgqO5SFylt
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Come and work @UCL_IfWH with myself and @Dr_RKarda on a hugely exciting preclinical gene therapy project! Research assistant and postdoc to be hired 🧬👩🔬🧑🔬
We have a new post-doctoral and research assistant positions open in my team. Pre-clinical gene therapy treatment for a rare neurological disorder. 🧬🧬 Please apply below; https://t.co/oCKZpjqh6Z
https://t.co/t333KjfSaa
@drelliechilcott @UCL_IfWH @UCLTRO
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With @jerry760 and team at @dukenus @kkh_sg doing what I do best - frowning while looking down a microscope #iugt #genetherapy @UCL_IfWH @ProfAhadRahim @DrGiuliaMassaro @Dr_RKarda @PrenatalTherapy @DrNLK0
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I'm pleased to share that I will be speaking at The Festival of Genomics & Biodata, taking place on the 29th-30th of January 2025 at ExCeL London. Registration is free for over 90% of attendees - register now to join us in January. https://t.co/LuMFjzyLBv
#FOG2025
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👋We have an update for you on the 'Novel Gene Therapy' research. For which Cavernoma Ireland is funding partner alongside Cavernoma Alliance UK & a philanthropist. This is the 1st gene therapy research to be taking place in the UK for hereditary brain cavernoma. @UCL_IfWH
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The group is expanding! 👇 New exciting post-doctoral researcher position available to study astrocytic GABA metabolism in cortico-subpallial organoids. This project is part of a larger programme assessing links between GABA as gliotransmitter and mental health.
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Our new pre-print paper on “AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome” is out🧬🧬; https://t.co/SZzZrKtOp4
@jantinaod @lifearc1 @GOSHCharity @DravetUK @DSFeu @UCL_IfWH @DNP_ICH @UCLIoN @_BSGCT @UCLTRO
biorxiv.org
Dravet syndrome (DS) is a severe childhood onset developmental and epileptic encephalopathy which leads to life-long disability. Symptoms usually manifest in the first year of life and include...
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We have a new pre-print paper! “AAV9-mediated targeting of natural antisense transcript as a novel treatment for Dravet Syndrome” https://t.co/i7BXaFuT3P
@lifearc1
@GOSHCharity
@DravetUK
@UCL_IfWH
@DNP_ICH
@UCLIoN
@_BSGCT
@UCLTRO
biorxiv.org
Dravet syndrome (DS) is a severe childhood onset developmental and epileptic encephalopathy which leads to life-long disability. Symptoms usually manifest in the first year of life and include...
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Today we are hosting our Inaugural Reproduction Symposium at @TheCrick and have invited University partners to present the most cutting-edge research in reproduction. Our symposium aims to foster collaboration and research between kindred research groups. #ReproSymp24
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Actually it was probably not a zoom. Or maybe my Pentax 80-200 at 80 - so I could attempt a rule of thirds, with the hazy sun, and the stones. The sun nearly 2/3rds to the right. The top of the stones nearly a 1/3rd up...
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Muscles 💪 and AAV 🦠 - what more could you ask for? Our preprint highlighting strategies for effective transduction of skeletal muscle with AAV with @wenanlan @J_N_Slayer @FrattaLab : https://t.co/BgdKC1g1Jt
@UCLIoN @UCLBrainScience @UCLDivofSurgery @TheCrick @UKDRI
biorxiv.org
Viral vector technologies based on adeno-associated virus (AAV) have demonstrated promising ability to deliver genetic cargo to a range of organs in vivo, with several novel candidates showing...
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I really wish more people knew about this before they flew off and left us humans alone. It was an alien spaceship posing as a rest stop near the A1.
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