James ODonnell
@ProfJSODonnell
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Joined December 2017
RT @BloodPortfolio: Mild isolated functional VWF defects in the 30 to 50 IU/dL range are common and are associated with significant bleedin….
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RT @RCSI_Irl: New RCSI research has identified a previously unrecognised subgroup of patients with the bleeding disorder von Willebrand dis….
rcsi.com
New research by RCSI has identified a previously unrecognised subgroup of patients with von Willebrand disease. More ...
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RT @UlsterUniSoNP: Celebrating the great news of promotion to Professor of nursing for our colleague @dodonnell22 @ulsterunisonp Congratul….
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RT @dodonnell22: Delighted to be promoted to Professor of Nursing. Thanks to everyone who has supported me and believed in me.
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RT @malecly: Montgomery Educational Symposium on Hemostasis (MESH) was a huge success thanks to the incredibly bright minds and warm hearts….
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RT @DurkanLab: President of Haematology Association of Ireland @Paulv8205 giving an overview of 25 years of the #HAI and recognition of Lia….
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RT @BloodJournal: BT200 interaction with the VWF-A1 domain in proximity to this lysine cluster significantly attenuates macrophage LRP1-med….
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RT @TFFVIIa: Very excited to share our science and kick off new collaborations. Coffee is also mentioned, which is excellent.
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RT @RCSIPharmBioMol: REMINDER: Our next #PBSResearch seminar series supported by @thermofisher is tomorrow Tues. 1st Oct. at 3pm in the Che….
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RT @flora_peyvandi: #BT200 prolongs VWF half-life by attenuating macrophage-mediated clearance and specifically the interaction of K1405-K1….
ashpublications.org
Key PointsA cluster of 4 lysine residues (K1405, K1406, K1407 and K1408) in the VWF-A1 domain constitutes a critical binding site for macrophage LRP1.BT200
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RT @ProfMakris: Valuable information on the mode of action of BT200 published in @BloodAdvances. It blocks VWF clearance through LRP1. BT20….
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RT @JTHjournal: 👀Let’s take a peek at the story that made our #october #coverart . In #vWD type vicenza, #vWF clearance is accelerated. How….
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RT @SETH__Oficial: ▶ Advanced analysis of platelet metabolism and mitochondrial function.Sonia Águila, @Sonia_AguilaM, Centro Regional de H….
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RT @BloodJournal: Novel functions for von Willebrand factor.#thrombosisandhemostasis #vascularbiology
https://t.co/….
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RT @RCSI_Irl: Dr Alain Chan Kwo Chion @RCSIPharmBioMol features in the @siliconrepublic list of researchers to follow 🔬. Based at @IrishCtr….
siliconrepublic.com
The world of research is an active and limitless realm, so who are the people keeping the wheel turning and changing how we live each day?
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RT @DiseasePrimers: The gene encoding von Willebrand factor is located on the short arm of chromosome 12, and a highly homologous pseudogen….
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RT @ibts_education: Prof. Hervig will be sorely missed by all in the IBTS. We wish him a very happy retirement!.
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RT @DiseasePrimers: von Willebrand factor synthesis occurs in endothelial cells and megakaryocytes as a single-chain polypeptide that, subs….
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RT @DiseasePrimers: Our NEW Primer on von Willebrand disease is live today!.By @OmidSeidi, Eikenboom, @cecile_denis, @VeronicaFlood18, @jam….
nature.com
Nature Reviews Disease Primers - von Willebrand disease (VWD) is the most common inherited bleeding disorder. VWD is characterized by defects in von Willebrand factor, the largest plasma...
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RT @JTHjournal: VWF-R1205H (Vicenza), known for causing enhanced clearance of VWF, . ▶️causes conformational changes in the VWF-D’D3 domain….
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