Pirkko Pussinen
@PirkkoPussinen
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Professor of Translational dentistry, University of Eastern Finland and University of Helsinki
Helsinki, Suomi
Joined November 2013
Genetiikka määrittelee myös vasta-ainetasoa parodontiitissa. @UniEastFinland @HelsinkiUniMed GWAS of Serum Antibodies to Microbial Biomarker Species of Periodontitis.
journals.sagepub.com
Serum antibody levels against microbial biomarkers of periodontitis, Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis, are associated especial...
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Juurihoito parantaa aineenvaihduntaa. Artikkelimme sai valtavaa huomiota kansainvälisessä lehdistössä, sitä siteerasi mm. Guardian, Washington Post ja Al Jazeera @HelsinkiUniMed @KingsCollegeLon @UniEastFinland
link.springer.com
Journal of Translational Medicine - Apical periodontitis (AP) is one of the most prevalent dental diseases. Its presence can increase systemic inflammatory burden and is associated with...
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Endodonttisella hoidolla on myös laajempia terveysvaikutuksia. @HelsinkiUniMed @KingsCollegeLon Successful endodontic treatment improves glucose and lipid metabolism: a longitudinal metabolomic study
pubmed.ncbi.nlm.nih.gov
Successful endodontic treatment in AP patients is associated with improved glucose and lipid metabolic profiles, and a reduction in systemic inflammation, suggesting a potential role in mitigating...
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Helsingin yliopiston hammaslääketieteellinen tutkimus sijoittui Shanghai-listalla sijalle 18. Vau! @HelsinkiUniMed
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Syljen LPS-mittaus = potentiaali dysbioosin mittari. @UniEastFinland @HelsinkiUniMed Oral Microbial Determinants of Saliva and Serum Lipopolysaccharide Activity - M. Manzoor et al. 2025
journals.sagepub.com
Lipopolysaccharide (LPS) is a virulence factor of gram-negative bacteria, and endotoxemia or translocation of LPS in serum plays a significant role in oral and ...
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Ehkä uusia Alzheimerin taudin biomarkkereita sylkitestistä? @karolinskainst @HelsinkiUniMed Elevated levels of salivary interleukin-34 in patients suffering from Alzheimer's disease - PubMed
pubmed.ncbi.nlm.nih.gov
Identifying reliable biomarkers for AD is crucial for early detection and intervention. This study suggests that salivary IL-34 could serve as a potential biomarker for AD.
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Parodontiitti ennustaa metabolista oireyhtymää erityisesti niillä, joilla on pienempi CVD-riski, eli naisilla ja tupakoimattomilla - Journal of Clinical Periodontology - Wiley Online Library https://t.co/MmfkyLoVDc
@UniEastFinland @HelsinkiUniMed
onlinelibrary.wiley.com
Aim To investigate whether periodontitis is associated with prevalent and incident metabolic syndrome (MetS). Materials and Methods The baseline study included 4183 individuals from a population-b...
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Uusi metagenominen analyysi hammasproteesien mikrobiomista ja suutulehduksesta. Metagenomic analysis of the denture-associated oral microbiome in patients with denture stomatitis @UniEastFinland @HelsinkiUniMed @manzoorap
pubmed.ncbi.nlm.nih.gov
Denture stomatitis (DS) is an inflammatory condition that affect denture wearers and is characterized by erythema of the mucosa opposing the denture. DS is often associated with oral microbiome...
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Hammasproteeseihin liittyvä suutulehdus rikkoo suun mikrobiomin rakenteen avaten tietä patogeenisille lajeille. @UniEastFinland @HelsinkiUniMed Metagenomic analysis of the denture-associated oral microbiome in patients with denture stomatitis
nature.com
Scientific Reports - Metagenomic analysis of the denture-associated oral microbiome in patients with denture stomatitis
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Laaja FinnGen-tutkimus endodonttisista hammasinfektioista paljastaa patogeneesin yksityiskohtia. @UniEastFinland @HelsinkiUniMed @FinnGen_FI Genome-wide association study of pulpal and apical diseases | Nature Communications
nature.com
Nature Communications - Here the authors aim to further increase our understanding of host genetic variants predisposition to endodontic infections and perform a GWAS on FinnGen participants with...
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Tähän asti suurin parodontiitin GWA-tutkimus osoittaa immuunivasteen tärkeyden tässäkin sairaudessa @UniEastFinland @HelsinkiUniMed @FinnGen_FI Journal of Clinical Periodontology - Wiley Online Library
onlinelibrary.wiley.com
Aim To perform a genome-wide association study (GWAS) for periodontitis in the FinnGen cohort, as genetic factors contribute to periodontitis. Materials and Methods We included nearly 250,000 Finn...
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Hammaspuutoksiin liittyy tulehduksellinen aineenvaihduntaprofiili. @UniEastFinland @HelsinkiUniMed Metabolic Profiling of Individuals with Missing Teeth and Tooth Loss
pubmed.ncbi.nlm.nih.gov
Missing teeth have been linked to incident cardiovascular disease, diabetes, and all-cause mortality. Our previous study revealed that signs of oral infections and inflammatory conditions (i.e.,...
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Last autumn FinnGen hit its target of sampling close to 10% of the Finnish population with more than 500,000 participants. We are happy to announce that the results based on the full cohort are now publicly available for the whole research community: https://t.co/c6lTge4h4t
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Meillä oli hyvä menestys FINDOS:n posterikilpailussa: 1. ja 3. palkinto. Ohjaajat ovat ylpeitä. @UniEastFinland @HelsinkiUniMed @UCLEastmanPerio @KatiOorni
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Lisää tietoa suun mikrobiomin valtavasta monimuotoisuudesta ja eri eliöiden välisestä suhteesta. @UniEastFinland @HelsinkiUniMed
pubmed.ncbi.nlm.nih.gov
Although knowledge of the role of the oral microbiome in ischemic stroke is steadily increasing, little is known about the multikingdom microbiota interactions and their consequences. We enrolled...
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Jos hampaita ei hoida vain säilyttääkseen ne, on muitakin hyviä syitä hoitaa niitä. @UniEastFinland
hs.fi
Parodontiitti koskee valtaosaa aikuisista, mutta sitä ei aina ymmärretä ottaa tosissaan, sanoo professori Pirkko Pussinen.
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