Pierre Sens
@PierreSens
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Theoretical Physicist CNRS/Institut Curie
Paris, France
Joined August 2018
📢 Applications for #PSLPhdTracks are open! Highly selective & taught in English, #PSLPhdTracks are 5-year programmes that prepare students for an international research career, in the academic or industrial sector. 🗓 Application deadline: 12.12.24 👉 https://t.co/mAxLH9yrvC
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In his new preprint Sami Al-Izzi (@samializzi, with Matthew Turner @TurnerSoftBio) shows that a simple membrane tube with unidirectional ion pumps forms a large vacuole that actively pump water out of the cell interior.
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Active cellular water pump for osmoregulation. Unicellular organisms in fresh water need to actively pump water out to balance the large flux of water coming in due to osmotic pressure difference. No molecular water pumps are known, so this water pump must be supramolecular.
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Congratulations to Jacques Prost. Onsager prize 2024 ! https://t.co/jfrHBvf85L.
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Really happy to have contributed to this fantastic work from @JorgeBarbazan and @PerezGonzalezCa , showing how CAFs can actively remodel tumors! With @PierreSens , we made some analysis about the in vitro system where CAFs confine clusters of cancer cells (CC). 1/4
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Need a better understanding of the relationship between the multiple spatial and temporal scales observed in a biological system? Join the next International Course of Institut Curie, 8-14 Nov. 2023, Paris. https://t.co/0s7genxvlo
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I am happy to see the first part of my PhD, dedicated to study the physical basis of the cell size scaling laws, now published in @eLife ! @PierreSens, @JFJoanny, @Lab_PCC, @institut_curie, @LabexCnS Magazine Insight -> https://t.co/tTF5jwsjuQ
https://t.co/W9bfid6y89
elifesciences.org
A theoretical model explains how protein density and nuclear to cell volume ratio are maintained during cell growth, discusses conditions under which this breaks down, and highlights the importance...
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👨🔬👏 Congratulations to Daniel Riveline & @PierreSens's teams for their newly published work at the frontier of #biology and #physic titled "3D single #cell migration driven by temporal correlation between oscillating force dipoles". 📕 @eLife 📰
#ResultatScientifique🔎 | Comment les cellules se déplacent-elles à force totale nulle ? 🤝 @CNRS @CNRS_Paris @CNRS_Alsace @unistra @Inserm @institut_curie @Sorbonne_Univ_ ✍️ Daniel Riveline et Pierre Sens 📕 @eLife | https://t.co/LfmIMK5U0X
https://t.co/sMUXuA0tFf
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Our theoretical answer to these questions (and others) is out on https://t.co/2gF7rHwpFT. Brilliant PhD work of @RomainRollin, co-supervised with @JFJoanny. More details in Romain’s thread.
biorxiv.org
The dimensions and compositions of cells are tightly regulated by active processes. This exquisite control is embodied in the robust scaling laws relating cell size, dry mass, and nuclear size....
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How come the size of the nucleus generally scales with the size of the cell, although the nucleus is packed with DNA and surrounded by a relatively stiff envelop?
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How do cells maintain a constant protein density during growth, although the protein content is very small (1% in number of that of other osmolytes) and does not directly control cell volume? Why does density homeostasis break down at senescence, and transiently at mitotic entry?
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My first preprint is out ! We (@PierreSens, J-F. Joanny and myself) investigate the physical origins of the universal laws linearly relating cell volume, nucleus volume, dry mass and their breakdown in senescence (dilution) and cancer (abnormal NC ratio). https://t.co/tydly5kumP
biorxiv.org
The dimensions and compositions of cells are tightly regulated by active processes. This exquisite control is embodied in the robust scaling laws relating cell size, dry mass, and nuclear size....
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Please RT: For those living in Paris, or willing to come and visit Paris for 1-2 days, here is an important announcement. Rob Phillips will give a series of 4 lectures at the Collège de France on Mondays 9, 16, 23 and 30 May. It's free, no registration needed. Just come and enjoy
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📢 2 weeks left to apply!!
We are hiring!! Please RT! 📢 👉 Ever wanted to put your hands inside a nucleus? How do you think a chromosome reacts when you pull on it? Join us at @Institut_Curie to study chromosome mechanics in live cells... 🧲🔬 https://t.co/XYrgprdejs
#3Dgenome #Mechanobiology
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Thank you @Fondation_BS for supporting our research @CNRS @institut_curie Check out this cool film (in French) about the lab! https://t.co/l7cQlVZH8g
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We are hiring!! Please RT! 📢 👉 Ever wanted to put your hands inside a nucleus? How do you think a chromosome reacts when you pull on it? Join us at @Institut_Curie to study chromosome mechanics in live cells... 🧲🔬 https://t.co/XYrgprdejs
#3Dgenome #Mechanobiology
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Join us for our 4th "Multiscale Integration in Biological Systems" course taking place from Nov. 4th-10th in @institut_curie. Info and link for virtual attendance: https://t.co/Z8m7Mbjggy Program: https://t.co/G8jO4F0K5t
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Qlife winter school: Active matter in biology. Application deadline Dec 5th.
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