Nature Communications - Lipid synthesis plays a central role in cell structure, signalling, and metabolism. Here, the authors report the abiotic formation of natural lipids in water using...

Dearomatization has emerged as a powerful tool for rapid construction of 3D molecular architectures from simple, abundant, and planar (hetero)arenes. The field has evolved beyond simple dearomatiza...

Dearomatization has emerged as a powerful tool for rapid construction of 3D molecular architectures from simple, abundant, and planar (hetero)arenes. The field has evolved beyond simple dearomatiza...

Bioorthogonal de novo phospholipid synthesis utilizing the reactions between hydroxylamine and α-ketoacids (KAs) or potassium acyltrifluoroborates (KATs) enables the rapid formation of biomimetic...

Reductive dearomatization has been a broadly explored means for rapid generation of sp3 complexity from simple planar arenes. Breaking the electron rich, stable aromatic systems requires strong...

Chiral quaternary α-aryl amino acids are biologically valued but synthetically challenging building blocks. Herein, we report a strategy for the synthesis of molecular architectures by unifying a...

Nature Communications - The synthesis of polycyclic structures bearing partially saturated (hetero)arenes is important as many of these structures have biological relevance. Here the authors...

While strategies involving a 2e− transfer pathway have dictated glycosylation development, the direct glycosylation of readily accessible glycosyl donors as radical precursors is particularly...

H/D exchange at formyl groups represents the straightforward approach to C-1 deuterated aldehydes. This transformation has been recently realized by transition metal and NHC carbene catalysis....

A mild, versatile organophotoredox protocol has been developed for the preparation of diverse, enantioenriched α-deuterated α-amino acids. Distinct from the well-established two-electron transforma...