Tom Parée
@PareeTom
Followers
49
Following
47
Media
2
Statuses
17
Postdoc at NYU. Evolutionary genetics. C. elegans. Namur, Paris, New York.
Joined July 2019
In our new review, we discuss evolution experiments that shed light on the evolution of sex and recombination, and illustrate key phenomena through simulations. Check it out!
academic.oup.com
Abstract. Sex and recombination generate genetic variation and facilitate adaptation by reducing selective interference, but they can also disrupt allelic
0
0
0
Selection Can Favor a Recombination Landscape That Limits Polygenic Adaptation. This is what we show in our recent article published in MBE, by using experimental evolution in C. elegans, genomics, and simulations.
0
0
0
I am thrilled to share this work conducted during my PhD. We observed that a mutation in rec-1, which modifies the recombination landscape of C. elegans, impairs adaptation BUT is favored by selection. How?.
biorxiv.org
Meiotic crossover positions are uneven along eukaryotic chromosomes, giving rise to heterogeneous recombination rate landscapes. Genetic modifiers of local and genome-wide crossover positions have...
0
0
3
Generate videos in just a few seconds. Try Grok Imagine, free for a limited time.
12
11
99
RT @biorxiv_evobio: #PeerReview from @ReviewCommons of 👉🏿 Genome-wide association and environmental suppression of the mortal germline phen….
0
1
0
Despite its drastic effect on crossovers' positioning, the rec-1 mutant does not impact fertility and embryonic lethality. rec-1 raises interesting questions. If the recombination landscape can be evolvable without direct fitness cost, why is it so conserved among nematodes?.
1
0
0
The wild-type C. elegans recombination landscape is characterized by a low recombining center flanked by recombinogenic arms. The rec-1 mutant eliminates this arm-center domain structure, though we show that its recombination landscape is not uniform either.
1
0
0
Is recombination rate diversity adaptive, and how does it evolve? These are the questions I address in my thesis. Here, we've estimated the first genome-wide genetic linkage maps of the rec-1 recombination modifier gene in C. elegans.
1
0
0
RT @martykardos: What is Ne, anyway? From Robin Waples.
academic.oup.com
Abstract. Few doubt that effective population size (Ne) is one of the most important parameters in evolutionary biology, but how many can say they really u
0
29
0
RT @biorxiv_evobio: The evolution of recombination in self-fertilizing organisms #biorxiv_evobio.
0
4
0
RT @biorxiv_evobio: Diversity and determinants of recombination landscapes in flowering plants #biorxiv_evobio.
0
3
0
RT @RomanStetsenko: In these dark times - when the homeland of my family is invaded by a dictator driven by nonsensical and deadly imperial….
0
16
0
RT @GeneticsGSA: Noble et al. report the expansion of the #Celegans multiparental experimental evolution (CeMEE) panel with new lines and n….
0
4
0