Conclusions：.In MDD patients, GDNF levels were associated with neural activity within the DMPFC subsystem of the DMN, which statistically mediated the link to rumination severity.#major_depressive_disorder #rumination

Results：MDD patients had lower GDNF and IL-8 levels than HCs. fALFF significantly interacted in DMN's DMPFC and MTL. Mediation by DMPFC neural activity linked GDNF to brooding rumination in MDD.#GDNF #psychoradiology #MDD.

33 MDD patients and 33 controls had fMRI during rumination task. RRS measured rumination tendency. DMN activity via fALFF and FC, serum GDNF and inflammatory markers were analyzed. Relationships between brain activity, GDNF, and RRS scores were examined.

Rumination is a pivotal psychopathological process in MDD. The neurotrophic hypothesis suggests that glial cell line-derived neurotrophic factor might play a role in brain dysfunction and clinical symptoms of MDD.However, the relationship remains unclear.

We are thrilled to share a new research published on Psychoradiology clarifying the relationship between peripheral GDNF levels, DMN subsystem activity, and rumination in MDD.🔗Click here to get more information:#major_depressive_disorder #rumination #GDNF

Ex vivo MRI integrates with histopathology and genetic analysis to link imaging findings with cellular, molecular, and genetic alterations, enhancing understanding of disease mechanisms and aiding biomarker discovery.#ex_vivo_brain #psychiatric_disorders.

Prospects of application in psychiatric disorders：.Ex vivo MRI is crucial for validating neuroanatomical abnormalities in mental disorders. The figure shows psychiatric disorder pathological changes and related MRI techniques.

Technical considerations in ex vivo brain MRI：.Technical considerations in ex vivo brain MRI involve optimizing postmortem specimen collection, fixation, MRI techniques for high image quality, and integration with histopathology and transcriptomics.

Introduction：.Ex vivo MRI offers high-resolution insights into brain microstructure, complementing in vivo MRI.This review introduces standardized ex vivo methods and applications in schizophrenia, MDD, and bipolar disorder.#ex_vivo_brain #psychoradiology.

Latest review summarized Ex vivo magnetic resonance imaging (MRI) on psychoradiological research. Click here for further information: #psychoradiology #magnetic_resonance_imaging #ex_vivo_brain #psychiatric_disorders

Conclusions：.Patients with drug-resistant epilepsies have global and segmental quantitative white matter tract anomalies, which suggests cerebral neural involvement in this disease. These abnormalities can vary regarding the postsurgical clinical outcome.

ResultsSignificant pre- and postsurgical abnormalities were seen, with increased MD and decreased FA,volume, and fiber number.TLE patients with seizure freedom had preoperative increased MD in specific tracts,while FLE showed postsurgical fiber increases.

Methods：.The study used automatic fiber quantification to assess white matter tracts in 8 frontal lobe epilepsy (FLE) and 12 temporal lobe epilepsy (TLE) patients pre- and post-surgery, comparing FA, MD, volume, and fiber number to 19 healthy controls.

Methods：.Using automatic fiber quantification to assess white matter tracts in 8 frontal lobe epilepsy(FLE)and 12 temporal lobe epilepsy (TLE) patients pre- and post-surgery, comparing FA,MD,volume, and fiber number to 19 healthy controls.#psychoradiolog.

Background：.This research aimed to evaluate the relationship between cerebral white matter quantitative anomalies and postoperative clinical outcomes in patients with drug-resistant epilepsies. #epilepsy_surgery #automated_fiber_quantification.

🚀New insights into drug-resistant epilepsy! .Latest research links cerebral white matter quantitative anomalies to postoperative clinical outcomes on drug-resistant epilepsies patients. Click at: #epilepsy_surgery #automated_fiber_quantification

Findings highlight the need for real-world classroom research and interdisciplinary collaboration. Combining multimodal technologies and longitudinal studies is crucial for fully understanding teaching and learning processes.

Five research clusters: cognitive processes, collaborative learning, real classroom learning, cognitive load, virtual reality, and child learning. They reflect growing portable tech use and a shift to naturalistic education approaches.#portable_EEG

Methods：.This study conducted bibliometric and content analysis on 135 Web of Science articles, examining publication trends, key contributors, and influential works. Keyword co-occurrence analysis identified five research trend clusters.#portable_EEG.

This review examines mobile psychophysiological technologies in education (2004–2023) using bibliometric and content analysis, highlighting the impact of portable tools on ecologically valid education and identifies key research themes to future studies.