OpenEye, Cadence Molecular Sciences
@OpenEyeSoftware
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OpenEye, Cadence Molecular Sciences: Computational molecular design with rapid, robust, scalable software, toolkits, and technology/design services
Santa Fe, NM
Joined November 2009
Want to learn how to increase throughput up to 5-10X higher and cuts costs by 50-80% over traditional equilibrium methods such as free energy perturbation (FEP) or thermodynamic integration (TI)? Ask us how!
eyesopen.com
FE-NES is 5-10X higher throughput and cuts costs by 50-80% compared to traditional equilibrium methods such as free energy perturbation (FEP).
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A huge thank you to everyone who joined us at miniCUP Osaka. Your energy and engagement made the event a massive success!
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We had another great science meeting at miniCUP Tokyo - thank you to everyone who attended and contributed to the discussion!
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There is still time to register for our miniCUP events in Tokyo and Osaka. Register here: https://t.co/fjum2NqBmG
#CompChem #ComputationalChemistry #DrugDiscovery #DrugDesign #MedChem #MolecularModeling #MolecularDynamics #創薬 #計算化学 #AI創薬 #メドケム #分子モデリング
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Our European team is excited to attend the #FestivalofBiologics on Sep 30-Oct 2 2025 in Basel. Stop by booth 273 to discuss how our work in AI and physics-based design for biologics can be applied to help solve some of your biggest development challenges!
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We are heading to Discovery On Target in Boston, Sept 22–25! Let’s talk molecular modeling, drug discovery, and innovation in pharma R&D. #BostonDOT #drugdiscovery
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What is next in drug discovery? Watch Geoff Skillman and Jeff Blaney of @genetech discuss that now! https://t.co/Cug1GCC6gj
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Why are problem solving courses so important for new scientists? Watch David LeBard and Ken Dill of @stonybrooku discuss that and the next era of drug discovery now! https://t.co/qC1mgGsaFR
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Affinity prediction, upgraded. Our 3D-QSAR model uses machine learning with shape + electrostatics to predict binding affinity with high accuracy—and includes error estimates to guide smarter decisions. Better predictions. Better prioritization. https://t.co/KdtCnoKVyg
eyesopen.com
OpenEye's 3D-QSAR Machine Learning predictions are on-par with, or better than, published methods.
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KRAS was “undruggable” for 30+ years. Learn how OpenEye's Cryptic Pocket Detection workflow found a novel pocket. 📣 Webinar: Drugging the undruggable: A highly accurate method for detecting and ranking cryptic pockets 📆 Aug 14 | ⏰ 11–11:30 AM EDT https://t.co/FS7pH0Egxt
eyesopen.com
Some proteins involved in life-threatening diseases have proved difficult to treat simply because a binding pocket for a molecular inhibitor could not be found. One classic example is the KRAS...
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Join Us & @EnamineLtd for an exclusive webinar to explore 3D molecular search + chemical space tools that speed up drug discovery. 📅 Register now: https://t.co/Uv7mFkLGp2
#DrugDiscovery #MedChem
us06web.zoom.us
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Our team will be presenting at ACS Fall 2025. Don't miss these exciting talks!
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OpenEye’s Non-Equilibrium Switching (NES) on the Orion® platform delivers fast, cost-effective binding free energy estimates—ideal for iterative lead optimization. Read the science brief to learn more! https://t.co/uTSQq4MqqQ
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OpenEye, Cadence Molecular Sciences recycled 1000lbs of e-waste. Read the story now! https://t.co/c6DNQAO2C9
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OpenEye, Cadence Molecular Sciences recycled 1000 pounds of electronic waste from the facility in Santa Fe, New Mexico.
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Ever stop to smell the flowers? Check out the wildflowers currently growing all over our Bis-BEE office location. See the pictures now!
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OpenEye, Cadence Molecular Sciences harvested leafcutter bees last fall. Adult bees emerged in the spring and pollinated wildflowers at the Bisbee campus.
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Recently, OpenEye, Cadence Molecular Sciences welcomed retired scientists and engineers for a tour at our Santa Fe office. Afterward, they participated in a scientific discussion with our team and offered wisdom from their careers.
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Register now for OpenEye's fall 2025 miniCUP events! Agenda: • Trillion-scale 3D virtual screening • CryoEM map fitting with weighted ensemble MD • 3D ML-driven lead optimization • Revealing cryptic pockets for new drug targets ... and much more! https://t.co/RiqToUUtGh
eyesopen.com
Connect with the OpenEye team at one of our upcoming miniCUP events in Boston, San Francisco or San Diego
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Preparing chemical databases for 2D and 3D search is laborious and costly - let us do the heavy lifting for you. Prepared vendor databases available for search on Orion and Orion Molecule Search, where we provide near-instant similarity search results. https://t.co/Ayw6swwkaw
eyesopen.com
Orion Molecule Search offers scientists, researchers, and educators to search commercially available compounds from various vendors all in one place — no need to visit multiple sites or prepare...
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We are excited for #RICT2025! Visit booth # 10 to learn how scientists are using our cryptic pocket detection on Orion to find previously hidden binding sites in proteins like KRAS. #DrugDiscovery
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There is still time to register for our webinar tomorrow: "Bayesian sampling in OMEGA for small molecule conformer generation" 🗓️ June 26 | 11–11:30 AM EDT https://t.co/4G95kIMjaa
eyesopen.com
The new Bayesian approach to generating conformers in OMEGA – our small molecule conformer generation tool – is particularly well-suited for applications like ROCS/FastROCS and structure-based...
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