Oncogenesis
@Oncogenesis_
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Open-access journal publishing research on the molecular basis of cancer
Joined June 2025
Check how the authors uncovered a crosstalk between epigenetic modifications and post-transcriptional regulations that provides new insights into how epigenetic pathways contribute to neuroblastoma malignancy.
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“Noncanonical PRC1.1 targets BTG2 to retain cyclin gene expression and cell growth in neuroblastoma”. 📣Takehiko Kamijo latest research is now available to read in #Oncogenesis . ▶️Read the full open access article here:
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Check why their findings underscore the potential of SMYD3 as a promising pharmacological target for endometrial cancer therapy.
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“SMYD3 promotes endometrial cancer through epigenetic regulation of LIG4/XRCC4/XLF complex in non-homologous end joining repair”. 🔷 Xiaoping Wan & Wen Lu latest research is now available to read in #Oncogenesis. ▶️ Read the full open access article here:
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Check the innovative strategy proposed by the authors to reactivate p53 by pharmacologically inhibiting FLT4 signaling — a promising new approach to suppress ALL cell proliferation.
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“FLT4 activation promotes acute lymphoid leukemia survival through stabilization of MDM2/MDMX and inactivation of p53”. 📣 Discover Casimiro Gerarduzzi's newest findings, now featured in #Oncogenesis!. ▶️ Read the full open access article here:
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Check how they demonstrate that dysbiosis of the lung microbiome is a contributing factor in tumor development and progression by promoting large inflammation of the microenvironment.
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“Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development”. Groundbreaking research led by Giorgio Trinchieri and Curtis Harris has been featured in #Oncogenesis. Read the full article here:
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Check how the authors used intestinal organoids with colorectal cancer (CRC) driver mutations as model system to investigate the mechanistic basis of TGF-β1-induced pEMT and collective invasion.
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“TGF-β signaling redirects Sox11 gene regulatory activity to promote partial EMT and collective invasion of oncogenically transformed intestinal organoids”. Andreas Hecht latest research available in #Oncogenesis. Read the full open access article here:
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Check how Multi-Omics Factor Analysis (MOFA+) was employed to integrate transcriptomic, proteomic, and metabolomic data obtained from the tumor tissues to identify naturally occurring long-term prognostic subgroups of Breast Cancer.
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“Comprehensive multi-omics analysis of breast cancer reveals distinct long-term prognostic subtypes”. Guro F. Giskeødegård’s recent study has been published in #Oncogenesis. Read the full open access article here:
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Check the biochemical and bioinformatic criteria that the authors use to distinguish functional miRNAs from mistakenly annotated RNA fragments.
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