9/In summary, both local and global reward learning changes during adolescence and are both linked to (slightly different subdivisions of) lateral prefrontal cortex in humans and macaques.

8/ … Phew, that tour de force does not even cover our big-data HCP neuroanatomy analysis or human neuropsychology results. For these and a fuller description of the above check out the paper.

7/Strikingly, the negative GRS effect contrasted with both previous studies and our own analysis of GRS effects in a large sample of non-human primates (same paradigm, same analysis), pointing towards a potentially meaningful species difference.

6/Interestingly, the influence of the global reward state (GRS) was negative and became more negative with age, meaning young adults, more than adolescents, were less likely to persist with an option if there were other valuable alternatives.

5/We showed that the influence of both local and global reward learning was greater in adults compared with adolescents. As people get older, they more strongly associate local rewards with actions.

4/To look into this this we used the same learning task originally developed in non-human primates to dissociate learning from immediate reward (local) and the overall reward state (global) and tested a large online sample of adolescents and young adults.

3/We know from monkey work that lateral prefrontal cortex is important for learning the consequences of our choices. Interestingly, those brain regions are some of the last to mature, suggesting that the supported learning mechanisms may continue to change during adolescence.

2/People often assume that teenagers struggle to learn from the consequences of their actions. But how exactly do adolescents differ from adults when they learn about what actions are good and what actions are bad? And how is that rooted in brain development?.

1/We are excited to share our recent @PLOSBiology paper: Local and global reward learning in the lateral frontal cortex show differential development during human adolescence Team effort by @mkwittmann @mscheuplein @SophieGGibbons +big thanks to @acmedsci.

RT @Alexandra_Pike: A bunch of @StokesNeuro's trainees (from many points in time) put together a list of '10 simple rules for a supportive….

RT @Malte_Woestmann: Our article "Ten simple rules to study distractor suppression“ is out in Progress in Neurobiology: .

RT @DrJoCutler: What a line up for day 1 of #CPPC! First day of in-person conference talks including - @lukejchang, @OlgaDalMonte1, @xiaosi….

TWO NEW STUDIES from my lab asking how decision-making strategies are linked to mental health in young people (11-17 yrs). Follow the links for more information AND

RT @fmrib_karla: Home working, shielding and anxiety around health are new to many of us, but not to those with compromised immune systems.….

Second, with @mkwittmann @mscheuplein @SophieGGibbons we show changes in credit assignment across adolescence as predicted by regional delays in grey matter maturation.

It has been a busy start to the year! First, @SophieGGibbons and I have a preprint out suggesting that OFC subregions mature at different rates across adolescence

RT @wadhamoxford: What happens in the brain when we make decisions? Wadham Lecturer MaryAnn @NoonanMP describes her studies exploring the….

Work-Life balance: On my days with the kids, I find myself in one of two states during the peaceful post-lunch nap hour: 1. Frantically checking emails/making figures/writing papers or 2. Asleep on Small's floor. I'd call that balanced!.

RT @fmrib_karla: Is this a perfect storm? Or is it a reckoning that has been staring us in the face for decades?.

Under normal circumstances I'm a bit twitter-shy. Perhaps fearful of falling into the void or just shouting at it. But as daily-life is now just me, Tiny, Small, Husband & (virtual) parents I'm going to make more of an effort with you lot. You're welcome!.