
Nilufer Rahmioglu
@Nilosh
Followers
457
Following
306
Media
75
Statuses
518
Genetic epidemiologist at the Centre for Human Genetics investigating genetics of endometriosis and comorbid conditions. Views are my own.
Oxford, UK & Nicosia, Cyprus
Joined April 2009
RT @horne_research: Excited to share our new @JAMA_current clinical review on #endometriosis. We cover pelvic pain, infertility, diagnostic….
0
15
0
@OxfordEndoCaRe @Ox_wrh @uk_biobank Individuals with #endometriosis have a moderately increased risk of autoimmune and inflammatory diseases through shared biological mechanisms. Greater clinical awareness is needed — and shared variants and pathways offer new treatment targets (9/9)@Ox_wrh @WellbeingofWmen.
0
1
2
@OxfordEndoCaRe @Ox_wrh @uk_biobank Shared risk variants were enriched across seven biological pathways. This suggests overlapping disease mechanisms between #endometriosis and immune diseases, with potential therapeutic targets (8/9).
1
1
2
@OxfordEndoCaRe @Ox_wrh @uk_biobank Multi-trait GWAS (#MTAG) and functional annotation (eQTL analysis) identified shared genetic variants between #endometriosis and #osteoarthritis, #rheumatoidarthritis and #multiplesclerosis. Notably, BMPR2 (2q33.1), BSN (3p21.31), MLLT10 (10p12.31) XKR6 (8p23.1) (7/9).
1
1
1
@OxfordEndoCaRe @Ox_wrh @uk_biobank Mendelian randomisation analyses suggested a causal relationship between #endometriosis and #rheumatoidarthritis (6/9).
1
1
1
@OxfordEndoCaRe @Ox_wrh @uk_biobank Conducted female-specific GWAS in @UK_Biobank on IBD, osteoarthritis(OA), ankylosing spondylitis, psoriasis, coeliac disease, multiple sclerosis(MS), rheumatoid arthritis(RA), and lupus. We found significant genetic correlations between endometriosis and OA, RA &MS (5/9).
1
0
0
@OxfordEndoCaRe @Ox_wrh We conducted analysis in 8,000+ women with #endometriosis and 64,000+ immune disease cases from @UK_Biobank, revealing that endometriosis cases have 30–80% increased risk of developing rheumatoid arthritis, multiple sclerosis, coeliac disease, osteoarthritis, and psoriasis (4/9).
1
1
1
@OxfordEndoCaRe @Ox_wrh Our new study investigates whether women with #endometriosis face a higher risk of autoimmune and inflammatory diseases — and whether shared genetic factors underlie this link. Grateful to @WellbeingofWomen for supporting this research (3/9).
1
1
1
@OxfordEndoCaRe @Ox_wrh Sex differences exist across immune conditions, many more common in females. Women with #endometriosis report autoimmune and inflammatory diseases more often. Female-specific genetic studies like ours help uncover the biology behind these links (2/9).
1
1
1
Hot off the press! Phenotypic and genetic association between #endometriosis and immunological diseases. @OxfordEndoCaRe @Ox_WRH Read our full paper 👉(1/9).
academic.oup.com
AbstractSTUDY QUESTION. Is there an increased risk of immunological diseases among endometriosis patients, and does a shared genetic basis contribute to th
3
1
3
We are currently planning an important study on #endometriosis and if you are living with endometriosis we need your input!.Click the link to participate in the survey:.→ We would really appreciate it!.
0
11
18
We are currently planning an important study on #endometriosis and if you are living with endometriosis we need your input!.Click the link to participate in the survey:
Do you have #endometriosis? Be part of our upcoming research study by sharing your thoughts - your voices are invaluable in designing our trial. Please click the link to participate @EndometriosisUK #EndometriosisAwarenessMonth
0
2
13
RT @OxfordEndoCaRe: It's #EndometriosisAwarenessMonth. Our group is committed to reducing diagnosis time, better imaging techniques, poten….
0
4
0
Petition: Increase funding for treatment and research into endometriosis
petition.parliament.uk
There is a lack of support or check ups for endometriosis. The disease is under researched, without a cure and can be left to worsen and can cause severe, chronic pain. More funding is needed to...
0
4
17
Day 2 in Istanbul @endometriozistr meeting kicks off with great talks on how to conduct clinical trials, PROMs, importance of including genetic data as part of trials to predict treatment response @OxfordEndoCaRe Katy Vincent @horne_research @DrLucyWhitaker
0
4
15
RT @OxfordEndoCaRe: Delivering the keynote lecture on the Genomics of Endometriosis & Adenomyosis is @Nilosh @endometriosistr @fitfindik ht….
0
3
0
RT @OxfordEndoCaRe: New publication from @GibbonsTatjana @Nilosh @KrinaZondervan & Christian Becker on how improving the use of blood bioma….
0
3
0
It is a great pleasure to be in İstanbul taking part in the #Endometriosis and #Adenomyosis Meeting organised by @endometriosistr, @OxfordEndoCaRe and @exppect teams on 15th year anniversary of Endometriosis and Adenomyosis Society Türkiye.
1
9
31
RT @neilajryan: Day 2 @BlairBellRS is well under way. AGM, hot topics & now hear from @Nilosh on the challenges of understanding the geneti….
0
3
0