🚨 New preprint! 🚨. Thrilled to share work from my postdoc in the @NCMLab @univofstandrews exploring the intrinsic properties of mouse gamma motoneurons during development, providing insight into how these cells are tuned to support motor function.

RT @JPhysiol: Congratulations & welcome to Dr Simon Sharples (@NeuroSharps) from @CincyChildrens who joins us as one of our 2025 Editorial….

Huge thanks to @WhelanLabYYC , @NCMlab , and @MatthewBroadhe6 and the X-less co-authors for the fantastic collaborations that made this possible!.

We hope this work sparks future research into the cell types driving episodic activity leading to their integration in computational models of the locomotor CPG.

These circuits also influence dorsal horn networks and can be entrained by sensory afferents.

By studying dopamine-elicited episodic rhythmic activity in isolated spinal cords of newborn mice, we found that episode-generating circuits arise from ventral horn interneurons across thoracic, lumbar, and sacral segments.

Locomotor CPGs are known for generating rhythm and pattern, but locomotor behaviors are often episodic. The circuits behind this remain poorly understood.

🚨 New Research Alert! 🚨. Thrilled to share my final PhD paper—also my first as corresponding author, recently published in @iScience! We investigated spinal circuits that contribute to the generation of episodic locomotor activity.

RT @gregorypearcey: Abstract submission is live for the 2025 @MotoNeuronSoc meeting in St. John’s, Newfoundland. Deadline for submissions i….

RT @gregorypearcey: Hats off to UG Honours student, @emmaraielene, for designing this year’s @MotoNeuronSoc meeting logo, which we will hos….

Such a pleasure to work together on such a cool project, drawing expertise from collaborators from St Andrews, Case Western Reserve, Athens, and Calgary!.

I am grateful for funding support provided by @CIHR_IRSC , @CarnegieUKTrust , and @TenovusScotland during the completion of this work!.

🚨 New research! 🚨 . We uncovered a novel spinal pathway that amplifies breathing, revealing how cholinergic interneurons boost motor neuron output for high-intensity respiratory demands. @NCMlab @st_psy . 👉 Read more:

RT @AllodiLab: A PhD position is available in my lab. This is a collaborative project with the Gunn-Moore lab at University of St Andrews.….

Oh wow! So cool! Nice to see the full story finally out!

RT @PhrenicRanatomy: Calling all our control of breathing folks! With the restructuring of the RIBT study section, please consider signing….

Thanks to everyone for coming to my poster @SfNtweets. Unfortunately, I have tested positive for COVID this morning. Although I was masked at my poster, if we were in close proximity during the meeting, please take care and I hope that I didn't manage to share it! So sorry!! 😔.

Of course, thanks to @CIHR_IRSC for supporting me during my postdoc and providing funds to attend this meeting!.

Happening now a poster board J8! Come check me out @SfNtweets!

Come check out my poster on Wednesday morning if you want to learn a bit about electrophysiological properties of (what I think are) gamma motoneurons