Néstor García Rodríguez
@NestorGarRod
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EMERGIA researcher @unisevilla and @cabimer. Interested in genome instability during replicative stress.
Joined September 2018
Delighted to announce our latest publication @NAR_Open about the contribution of EXO1 and DNA2 on expanding PrimPol-generated ssDNA gaps, thus triggering robust ATR activation and facilitating gap repair mechanisms. @cabimer @unisevilla
academic.oup.com
Abstract. DNA replication faces challenges from DNA lesions originated from endogenous or exogenous sources of stress, leading to the accumulation of singl
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Our PLAMseq paper is out today in @ScienceAdvances . We developed a TurboID-based protein-genomic approach to map proteins and protein interactions in the genome. Validated with CTCF and RNApolII. Applied to map Histone H1 SUMOylation genomic loci. https://t.co/7wDxkMLt2E
science.org
PLAMseq enables performance of genomics and proteomics of chromatin-associated proteins and protein interactions simultaneously.
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Happy to see our collaboration with @juanes_lab finally out at Journal of Experimental & Clinical Cancer Research! https://t.co/exNzQATRWU
link.springer.com
Human dihydroorotate dehydrogenase (DHODH) is the rate-limiting enzyme in pyrimidine de novo synthesis and represents a promising target for cancer therapy. However, current inhibitors of DHODH have...
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Los zafarranchos de limpieza del @Ayto_Sevilla @jlsanzalcalde duraron dos días. Es insoportable el olor de la calle José Maluquer.
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A fully-funded 4-year PhD position is opening in my lab at @cabimer . Please share!!! PostDoc inquiries are also welcome BTW!!!
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Today, Iria Domínguez-García, a PhD student in my lab at @cabimer @unisevilla , presented our latest advances on the regulation of ssDNA gap processing at @SEBBM_es
Towards the understanding of ssDNA processing and its connection with cancer por Nieves Iria Domínguez #47congresoSEBBM
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Come to join us at this fantastic workshop at @cabimer on October 17th. @GenomaHubCSIC
Save de date! Join us at @cabimer on October 17th for the @GenomaHubCSIC Workshop in "Genome Dynamics in Development and Disease". Slots available for talks! Registration opens soon!!
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Excited to share our new preprint! We asked: what is the phenotype of non-transformed breast epithelial cells expressing a mono-allelic truncating BRCA2 variant? The answer is, it depends on the variant. 1/3 https://t.co/mc5vsYv9oe
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New preprint from the Lab at @cabimer. We present PLAMseq, using TurboID to do like ChIPseq and proximity proteomics in the same protocol with extra powers like mapping protein interactions in the genome. https://t.co/p5JDNuvBri
biorxiv.org
Chromatin Immunoprecipitation (ChIP) and Co-Immunoprecipitation (CoIP) assays are common approaches to characterize the genomic localization and protein interactors, respectively, for a protein of...
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Happy to see this collaboration finally out. SRSF2 overexpression induces transcription-/replication-dependent DNA double-strand breaks and interferes with DNA repair pathways to promote lung tumor progression
academic.oup.com
Abstract. SRSF2 (serine/arginine-rich splicing factor 2) is a critical regulator of pre-messenger RNA splicing, which also plays noncanonical functions in
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POSTDOC position available in my group @cabimer @unisevilla . Please spread the word! Contact: nestor.garcia@cabimer.es
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Anoche mi lab al completo estuvo acompañando a Lola, estudiante de TFG y galardonada con una beca de Prácticas de Laboratorio AECC 2024, en la Gala de Premios Contra el Cáncer en el Alcázar de Sevilla. Gracias @ContraCancerEs por el apoyo a la investigación! @cabimer @unisevilla
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Happy to be awarded with a Consolidación investigadora grant to continue exploring ssDNA gap biology at @unisevilla and @cabimer. A postdoc position will be advertised soon. Stay tuned!
ℹ️ La @AgEInves publica la propuesta de resolución provisional de la convocatoria 2024 de ayudas para incentivar la consolidación investigadora. 🔗 https://t.co/YcBNfs68fy 💰 41,9 M€ para consolidar la carrera de 221 investigadores/as en España.
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In Cordoba enjoying diner with some of top Spanish scientists in the genome instability field. I had the opportunity to show how do we funcionally study VUSes in BRCA2 in @IRSantPau. Thanks Andrés Aguilera, @cabimer Director, for leading this network and organizing this meeting.
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Please RT. Are you interested in performing your master thesis with us @imbmainz? We have exciting projects on nuclear myosin VI in genome stability. Details below https://t.co/I9Z7k0KAqM If interested please apply via the link or contact me directly.
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We still have some places available for our Epigenetics workshop at beautiful Baeza (Spain). There will be a shuttle coach from Madrid. If you need any information please contact me. Register by 16th of September at https://t.co/Y1fkYYVuZe
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Nos han robado el coche en Santa Justa-Sevilla Ford Kuga Gris matricula 1652LLT. Porfa, si lo veis escribidme al mail y dadle difusión. danielgomezcab@gmail.com. Ya esta denunciado.#Sevilla @policialocal @policia #SevillaHoy
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Estación de recarga de vehículo eléctrico recién instalada en Carretera de Carmona y ya han cortado la manguera. 🤦🏻♂️Sevilla imparable @Ayto_Sevilla @jlsanzalcalde
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Extremely happy to be awarded with my first national grant!🥳🥳 This year has been almost perfect for me work-wise!
⚠️La @Ageinves publica la Propuesta de resolución provisional de la convocatoria 2023 de Proyectos Generación de Conocimiento https://t.co/aGzODIDXuI Abrimos hilo (1 de 3) 💰 655 millones de euros, mayor presupuesto de su historia aumentado un 30% desde 2018 ➡️Más de 3100
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👇👇👇 Un jerezano participa en un estudio que avanza en el tratamiento del cáncer de mama https://t.co/sCPkwGp3SJ vía @diariodejerez @cabimer @unisevilla @InvestigaUS
diariodejerez.es
Néstor García Rodríguez y su equipo del Centro Andaluz de Biología Molecular y Medicina Regenerativa descubren una nueva debilidad en estas células tumorales, lo que abre la posibilidad de desarrol...
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