Neha Kapate, PhD
@NehaKapate
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immuno-engineering, cell therapies, drug delivery | by way of @MIT_HST Medical Engineering + @CMU_ChemE @CMU_BME | views my own
Cambridge, MA
Joined April 2018
Defended my PhD from @MIT @mit_hst this week! Still reeling with gratitude from the outpouring of love. Could not have completed this journey without a village of support: mentors, family, friends, colleagues @SMitragotri @JennGuerriero @MrJeffKarp @wyssinstitute @hseas @MIT_IMES
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RT @MaithiliJoshi_: Excited to share our review on hemostatic agents, where we summarize trends in 54 approved hemostats and 75 active clin….
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RT @wyssinstitute: What good is an empty backpack? Turns out, they can treat cancer. Researchers at the Wyss and @hseas discovered that at….
nature.com
Nature Biomedical Engineering - The intravenous injection of neutrophils bearing discoidal polymer microscale ‘patches’ on their surfaces reduces tumour burden in mice owing to the...
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RT @ninadkumbhojkar: Proud to share my PhD research from @SMitragotri’s group published recently in @natBME! We show that neutrophils, acti….
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RT @wyssinstitute: Remember, you can vote in #STATMadness once a day! Check out Wyss entries in matchups 7, 9, and 27 with work from the la….
statnews.com
Who will be the 2025 MVP of health and medicine? STAT Madness is a bracket-style tournament to find the best innovations in science and medicine from
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RT @SMitragotri: It’s March 1st! Our backpacks for treating multiple sclerosis are in the running in #STATMadness (matchup #7). Vote to hel….
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RT @wyssinstitute: Happy March! It's time for #STATMadness. The Wyss has three entries this year - ovarian organoids, melanoma treatment mo….
statnews.com
Who will be the 2025 MVP of health and medicine? STAT Madness is a bracket-style tournament to find the best innovations in science and medicine from
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RT @wyssinstitute: In @PNASNews Nexus, Wyss researchers led by @SMitragotri used macrophages with microparticle "backpacks" to reduce brain….
academic.oup.com
Abstract. Traumatic brain injury (TBI) is a debilitating disease with no current therapies outside of acute clinical management. While acute, controlled in
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RT @RickLiaoPhD: I’m excited to have our manuscript out demonstrating the potential of backpack-augmented macrophages for the treatment of….
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RT @wyssinstitute: Our fourth-most-read story of the year was about cellular backpacks that use myeloid cells bound to drug delivery microp….
wyss.harvard.edu
By Benjamin Boettner (BOSTON) — Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and...
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This work would not have been possible without co-lead @RickLiaoPhD, TBI expert @costinebartell, and a collaborative team of researchers in @SMitragotri lab (@hseas + @mit_hst) and @MGHNeurosurg. Story:
wyss.harvard.edu
By Lindsay Brownell (BOSTON) — Scientists have created a new treatment for traumatic brain injury (TBI) that shrank brain lesions by 56% and significantly reduced local inflammation levels in pigs....
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These results show the use of cell therapy intervention for a large animal model of TBI and highlight the potential of macrophage-based therapy. This is promising, given that TBI affects >3 million in the US annually, with no current therapies beside acute symptom management.
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Excited to share the 2nd part of my thesis! We demonstrate that macrophages attached with anti-inflammatory particles ("backpacks") infiltrate into the brain after traumatic brain injury and reduce lesion volume by 56%. @SMitragotri @hseas @wyssinstitute
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RT @LIWENWANG7: Look at these particles that resemble many little planets (so cute!). They are actually cells with disk-shaped microparticl….
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RT @wyssinstitute: TBIs can cause lasting damage, but stopping the brain inflammation they cause is hard. A team at the Wyss, @hseas & @Mas….
wyss.harvard.edu
By Lindsay Brownell (BOSTON) — Scientists have created a new treatment for traumatic brain injury (TBI) that shrank brain lesions by 56% and significantly reduced local inflammation levels in pigs....
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RT @wyssinstitute: Even mild TBIs can cause lasting damage, and most are never diagnosed. A team at the Wyss, @hseas, & @BostonChildrens c….
wyss.harvard.edu
By Lindsay Brownell (BOSTON) — Researchers have created a new brain imaging method that allows mild traumatic brain injuries (mTBIs) to be diagnosed, even when existing imaging techniques like...
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RT @MorganEJanes: Curious about the clinical status of cancer vaccines? We analyzed 360 active clinical trials to paint a comprehensive pic….
aiche.onlinelibrary.wiley.com
Vaccines are an important tool in the rapidly evolving repertoire of immunotherapies in oncology. Although cancer vaccines have been investigated for over 30 years, very few have achieved meaningful...
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RT @KoladeAdebowal1: Paper w/ @JennGuerriero, @SMitragotri! We find that macrophage tumor transport + kinetics (TK) depend on the phenotype….
pubs.aip.org
Long-term remission in cancer patients treated with ex vivo bona fide M1-induced macrophages has been poor, and the reasons behind this are not understood. Inje
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RT @JohnRClegg: Postdoc position available in my laboratory at the Univ. of Oklahoma on CNS drug delivery, monocyte/macrophage immunotherap….
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RT @MaithiliJoshi_: Excited to share our review on PEGylated therapeutics where we summarize diverse PEGylation strategies, key advantages….
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RT @SMitragotri: Congratulations @SupriyaPrakash_ on successfully defending your PhD dissertation! Amazing work demonstrating the power of….
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