A narrative review outlines how different isolation modalities of #meniscus fibrochondrocytes generate molecularly and functionally distinct cell populations, which can be leveraged for meniscus #tissueengineering and #repair. #bioengineering.

Cell therapy for neurological damage after #cardiacarrestis advancing. The study shows hypoxia-preconditioned BMSCs significantly reduce neuronal pyroptosis via the MAPK/NF-κB pathways and mitochondrial ROS suppression. #neuroprotection #stemcelltherapy.

Unraveling the complex world of #MyastheniaGravis #Biomarkers! This review highlights key diagnostic tools like anti-acetylcholine receptor antibodies & repetitive nerve stimulation tests. #Neuroscience.

New research reveals a potential link between maternal allergic asthma and increased #autismspectrumdisorder risk in offspring! This may alter fetal #Neurodevelopment, and immune dysregulation & microglia changes could be key factors.

#Astrocytes in the ventrolateral preoptic nucleus are vital for #sleep homeostasis, sensing extracellular glucose levels and releasing adenosine to drive sleep, by inhibiting wake-promoting neurons and activating sleep-promoting ones.

Discover how robot-assisted minimally invasive techniques are transforming peripheral nerve microsurgery! This review highlights the precision, safety, and aesthetic advantages of these advanced methods. #RobotAssistedSurgery #PeripheralNerve.

Neurodegenerative diseases and metabolic disorders like diabetes are linked by oxidative stress. AI and machine learning are revolutionizing our understanding of these conditions by analyzing complex pathways. #HealthTech #AInomics #MedGasRes.

Learn about the #DrugDesign and redesign journey for #TransthyretinAmyloidosis! Researchers develop new transthyretin kinetic stabilizers, from tolcapone to M-23 and PITB. Molecular dynamics simulations guided the creation of potent transthyretin binders.

#HER096, a brain - penetrating neurotrophic factor mimetic derived from CDNF, shows promise. It can be administered subcutaneously, cross the blood - brain barrier, and may modify disease progression.

Ferroptosis, an iron-driven cell death mode, plays a crucial role in osteogenic differentiation. Understanding its link with bone cells could revolutionize bone defect healing. #BoneRegeneration #Orthopedics #RegenerativeMedicine.

Anti-amyloid antibodies like aducanumab & lecanemab show promise in clearing amyloid plaques, yet debate persists on their clinical impact. Meta-analysis highlights their effects, risks, and the role of APOE-ε4. #Alzheimers #Neuroscience #AβTherapy.

Mitochondrial epigenetics is revolutionizing our understanding of aging! From mtDNA methylation to non-coding RNA roles, new insights reveal how mitochondrial-nuclear crosstalk drives age-related diseases. #AgingResearch #Epigenetics #Mitochondria.

Say goodbye to harsh chemo side effects! Engineered Metal–organic frameworks are disrupting cancer cells by messing with their iron balance, triggering ferroptosis. It's like giving cancer cells a taste of their own medicine. #cancercure #MOFmagic.

💡Discover the role of #TSPO in #neurodegeneration! This protein impacts mitochondrial health and neurosteroidogenesis, showing promise in #AlzheimersResearch . TSPO ligands may reduce cognitive deficits and amyloid-beta levels.

The #DISCO database is revolutionizing #SingleCellRNASeq! With over 100 million cells and 461 cell types, it’s a game-changer for analyzing cellular heterogeneity. Its user-friendly tools and standardized data make complex analyses accessible.

Peripheral amyloid-β aggregates may act as “seeds,” potentially inducing brain amyloidosis. This mini-review explores the prion-like features of Aβ and its implications in Alzheimer’s disease pathology. #AlzheimersDisease #AmyloidBeta #Neurodegeneration.

🚀A recent study found that most people score below 50% on neurodegenerative diseases awareness, highlighting the urgent need for health education programs in Saudi Arabia. #Neurology #SaudiHealth.

💡New glucocerebrosidase antibodies are set to transform Parkinson’s research! These rigorously validated tools enable deeper exploration of the GBA1-Parkinson’s connection. #ParkinsonsResearch #Neuroscience #GBA1.

💡🧠 Unlocking the secrets of gene expression in the brain just got a boost! New methods to extract polyribosomes from astrocytes are revolutionizing our understanding of translation regulation. #Neuroscience #GeneExpression #BrainResearch.

🔑✨ Traditional mineral drugs held the key to cutting-edge gas therapy. By releasing gasotransmitters like H₂S and H₂, these age-old remedies are revolutionizing anti-inflammatory treatments!.#MedicalGasResearch #Gasotransmitters #Nanomedicine.