NRPSpapers
@NRPS_papers
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Twitterbot of nonribosomal or nrps or non-ribosomal in #Pubmed created and curated by [email protected]
Newcastle
Joined September 2014
Interested in natural products, high-value chemicals and green chemistry? PhD available with Paul Race, @sellars_j and myself.
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Bacillus velezensis BE2 controls wheat and barley diseases by direct antagonism and induced systemic resistance
pubmed.ncbi.nlm.nih.gov
Wheat and barley rank among the main crops cultivated on a global scale, providing the essential nutritional foundation for both humans and animals. Nevertheless, these crops are vulnerable to...
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PEARL-catalyzed peptide bond formation after chain reversal during the biosynthesis of non-ribosomal peptides
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Brevicidine acts as an effective sensitizer of outer membrane-impermeable conventional antibiotics for Acinetobacter baumannii treatment
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Manipulation of GameXPeptide synthetase gene expression by a promoter exchange alters the virulence of an entomopathogenic bacterium, Photorhabdus temperata temperata, by modulating insect immune responses
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Whole genome sequencing and annotation of Aspergillus flavus JAM-JKB-B HA-GG20
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Biosynthesis of Strained Amino Acids Through a PLP-Dependent Enzyme via Cryptic Halogenation
pubmed.ncbi.nlm.nih.gov
Amino acids (AAs) are modular and modifiable building blocks which nature uses to synthesize both macromolecules, such as proteins, and small molecule natural products, such as alkaloids and non-ri...
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Detection of non-ribosomal and polyketide biosynthetic genes in bacteria from green mud crab Scylla serrata gut microbiome and their antagonistic activities
pubmed.ncbi.nlm.nih.gov
Multi-modular enzyme complexes known as non-ribosomal peptide synthetases (NRPSs) and polyketide synthetases (PKSs) have been widely reported in bacteria that produce secondary bioactive metabolites...
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Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs)
pubmed.ncbi.nlm.nih.gov
Tridecaptins comprise a class of linear cationic lipopeptides with an N-terminal fatty acyl moiety. These 13-mer antimicrobial peptides consist of a combination of d- and l-amino acids, conferring...
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Investigation of the potential of Brevibacillus spp. for the biosynthesis of nonribosomally produced bioactive compounds by combination of genome mining with MALDI-TOF mass spectrometry
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Ribosomal protein L8 regulates the expression and splicing pattern of genes associated with cancer-related pathways
pubmed.ncbi.nlm.nih.gov
RPL8 might affect the phenotypes of cancer cells by altering the transcriptome profiles, including gene expression and splicing, which provides novel insights into the biological functions of RPL8 in...
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Draft genome sequence data of the endophytic actinobacterium Streptomyces justiciae WPN32, a potential bioactive compounds producer
pubmed.ncbi.nlm.nih.gov
Streptomyces justiciae WPN32 is an endophytic actinobacterium isolated from the rhizosphere of turmeric field soil at the Botanical Garden of Suranaree University of Technology (Nakhon Ratchasima...
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Complete Genome Sequence and Pan-Genome Analysis of Shewanella oncorhynchi Z-P2, a Siderophore Putrebactin-Producing Bacterium
pubmed.ncbi.nlm.nih.gov
In this study, we reported the complete genome sequence of Shewanella oncorhynchi for the first time. S. oncorhynchi Z-P2 is a bacterium that produces the siderophore putrebactin. Its genome consists...
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Analysis of the vibrioferrin biosynthetic pathway of Vibrio parahaemolyticus
pubmed.ncbi.nlm.nih.gov
Siderophores are small-molecule iron chelators produced by many microorganisms that capture and uptake iron from the natural environment and host. Their biosynthesis in microorganisms is generally...
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Synthetic ramoplanin analogues are accessible by effective incorporation of arylglycines in solid-phase peptide synthesis
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Siderophore-synthesizing NRPS reprogram lipid metabolic profiles for phenotype and function changes of Arthrobotrys oligospora
pubmed.ncbi.nlm.nih.gov
The objective of this paper is to explore the function of the AOL-s00215g415 (Aog415) gene, which encodes for the synthesis of siderophore in the nematode trapping fungal model strain A. oligospora,...
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Resilience and Ethics in Nursing Education and Practice: Needs and Opportunities
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Mimicking Nonribosomal Peptides from the Marine Actinomycete Streptomyces sp. H-KF8 Leads to Antimicrobial Peptides
pubmed.ncbi.nlm.nih.gov
Microorganisms within the marine environment have been shown to be very effective sources of naturally produced antimicrobial peptides (AMPs). Several nonribosomal peptides were identified based on...
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Commensal production of a broad-spectrum and short-lived antimicrobial peptide polyene eliminates nasal Staphylococcus aureus
pubmed.ncbi.nlm.nih.gov
Antagonistic bacterial interactions often rely on antimicrobial bacteriocins, which attack only a narrow range of target bacteria. However, antimicrobials with broader activity may be advantageous....
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A niche-derived non-ribosomal peptide triggers planarian sexual development
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