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Nicola Marchese, MD Profile
Nicola Marchese, MD

@NMarcheseMD

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Co-founder @ The Scenarionist | Subscribe to my newsletter, read by 2.3K+ Deep Tech founders & investors focused on industrial ventures: https://t.co/4kXN29X0mH

Italy
Joined September 2019
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@NMarcheseMD
Nicola Marchese, MD
1 month
AI agents, multimodal models, and quantum breakthroughs aren’t sci-fi—they’re powering what’s next for #DeepTech, #AI, and #Innovation. The future isn’t buzzwords but compounding breakthroughs. Where are the B2B builders this week? #technology #DeeptechStartups
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@NMarcheseMD
Nicola Marchese, MD
1 month
The next wave of US #deeptech will define not just markets, but entire industries. From quantum breakthroughs to tech resilience, the future belongs to founders building what no one else dares. If you're watching venture—this is where to look. 🚀 #hardtech #industrialtech
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@NMarcheseMD
Nicola Marchese, MD
1 month
🏗️ Pilot or Proof of Concept—Do You Know the Difference in #Construction? #Startups #Venturecapital
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@NMarcheseMD
Nicola Marchese, MD
1 month
4. Stay flexible. Pivots can turn roadblocks into wins. Plus, use techno-economic analysis to show your model works.
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@NMarcheseMD
Nicola Marchese, MD
1 month
3. Map the journey: lab → pilot → production. Investors want to see your roadmap before you build the factory.
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@NMarcheseMD
Nicola Marchese, MD
1 month
2. Operations > science at scale. Once you’re growing, logistics and execution outweigh lab breakthroughs. Plan for it.
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@NMarcheseMD
Nicola Marchese, MD
1 month
1. Don’t over-engineer. A rough MVP can validate your market faster than a perfect prototype. Focus on proving demand early.
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@NMarcheseMD
Nicola Marchese, MD
1 month
Moving from lab to production is brutal. It’s not just about the tech—it’s supply chains, pilots, and a techno-economic model that proves you can deliver.
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@NMarcheseMD
Nicola Marchese, MD
1 month
🧪 Deep tech #founders: Got a killer prototype? That’s just the start. Scaling to a factory is where your #startup becomes investable. Here’s what it takes. 🧵👇
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@NMarcheseMD
Nicola Marchese, MD
1 month
Full August analysis in Deep Tech Monthly in #Review 👉
Tweet card summary image
thescenarionist.com
Field Notes from The Scenarionist. A Strategic Recap for Builders and Backers
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@NMarcheseMD
Nicola Marchese, MD
1 month
3) #Space = workflows. From navigation to EO to #defense: less about pixels, more about underwriting + compliance. Gravity wins.
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@NMarcheseMD
Nicola Marchese, MD
1 month
2) Autonomy = brains, not bodies. Robot ‘brains’ with cross-form-factor SLAs took center stage. Acquisitions pulled perception into fleets.
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@NMarcheseMD
Nicola Marchese, MD
1 month
Why it matters → Delivery guarantees (power, latency, uptime) now drive #capital allocation more than model size.
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@NMarcheseMD
Nicola Marchese, MD
1 month
1) Compute = collateral. Capital follows electrons, availability, latency. #GPUs underwritten like turbines. Sovereigns back siting + firm power.
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@NMarcheseMD
Nicola Marchese, MD
1 month
Three signals emerged from our August #DeepTech watch. TL;DR 👇
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@NMarcheseMD
Nicola Marchese, MD
2 months
Is Your Gross Margin VC-Eligible? 💰 #Startups #fundraising #venturecapital
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@NMarcheseMD
Nicola Marchese, MD
2 months
In #Deeptech Capital intensity isn't inherently a bad thing—if you know how to manage it.👇
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@NMarcheseMD
Nicola Marchese, MD
2 months
Full episode link 👇 https://t.co/fXmmHg54cf
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@NMarcheseMD
Nicola Marchese, MD
2 months
Don’t Treat Farmers Like Beta Testers—Make Them Co-Innovators 🚜 Our latest #DeepTechCatalyst episode with Ana Ward (Yanmar Ventures) dives into how trust and on-site collaboration turn AgTech pilots into real partnerships. Link in first comment. #AgTech #Startups #DeepTech
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