Mycobacterium Papers
@MycobactPapers
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A daily collection of papers relating to Mycobacteria. I am a robot 🤖, but sometimes I break!
London, England
Joined April 2016
Retrospective analysis of the clinical utility of multi-cytokine profiles in smear-negative pulmonary tuberculosis
pubmed.ncbi.nlm.nih.gov
A multi-biomarker approach combining these cytokines demonstrates enhanced diagnostic accuracy for tuberculosis.
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Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery anddelivery of novel cargoes to the Mtb surface
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Conversion or reversion of interferon gamma release assays for Mycobacterium tuberculosis infection: a systematic review and meta-analysis
pubmed.ncbi.nlm.nih.gov
IGRA conversion is less common than reversion, and frequently transient. Research is needed to determine whether individuals with reversion would benefit from tuberculosis-preventive treatment....
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The inflammasome adaptor pycard is essential for immunity against Mycobacterium marinum infection in adult zebrafish
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Complete genome sequence of the type strain of Mycobacterium montefiorense, strain ATCC BAA-256
pubmed.ncbi.nlm.nih.gov
Mycobacterium montefiorense, a nontuberculous mycobacterium, is a causative agent of mycobacteriosis in aquatic animals, its type strain M. montefiorense ATCC BAA-256 being isolated from a moray eel....
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Orthogonal Deprotection of Photolabile Protecting Groups and Its Application in Oligosaccharide Synthesis
pubmed.ncbi.nlm.nih.gov
We herein report for the first time the inter- and intramolecular orthogonal cleavage of two ortho-nitrobenzyl (NB) analogues. It is shown that the nitroveratryl (NV) group can be photolyzed with...
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Regulatory role of Mycobacterium tuberculosis MtrA on dormancy/resuscitation revealed by a novel target gene-mining strategy
pubmed.ncbi.nlm.nih.gov
The complex modulation mechanisms were implied by the strong bias distribution of MtrA binding sites in the noncoding regions, and 32.7% of the binding sites were located inside the target genes. The...
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Tuberculosis of the Cervical Vertebrae With Retropharyngeal and Parapharyngeal Abscesses Due to Staphylococcus aureus and Mycobacterium tuberculosis in an Adult: A Report of a Rare Case
pubmed.ncbi.nlm.nih.gov
Tuberculosis is a disease with presentations both in the lungs and at other extrapulmonary sites. While pulmonary tuberculosis constitutes a significant proportion of total tuberculosis cases,...
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Polymerase Chain Reaction (PCR) Profiling of Extensively Drug-Resistant (XDR) Pathogenic Bacteria in Pulmonary Tuberculosis Patients
pubmed.ncbi.nlm.nih.gov
Introduction Pulmonary tuberculosis (TB) remains a global health concern, exacerbated by the emergence of extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis. This study employs...
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Phenotypic characterisation of bovine alveolar macrophages reveals two major subsets with differential expression of CD163
pubmed.ncbi.nlm.nih.gov
Bovine alveolar macrophages (AMs) defend the lungs against pathogens such as Mycobacterium bovis (M. bovis), the causative agent of bovine tuberculosis. However, little is known about the surface...
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Phenotypic characterisation of bovine alveolar macrophages reveals two major subsets with differential expression of CD163
pubmed.ncbi.nlm.nih.gov
Bovine alveolar macrophages (AMs) defend the lungs against pathogens such as Mycobacterium bovis (M. bovis), the causative agent of bovine tuberculosis. However, little is known about the surface...
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Quantifying Viable M. tuberculosis Safely Obviating the Need for High Containment Facilities
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Improved Diagnosis and Treatment Monitoring of Tuberculosis Using Stool and the Tuberculosis Bacterial Load Assay (TB-MBLA)
pubmed.ncbi.nlm.nih.gov
The diagnosis and monitoring of tuberculosis treatment is difficult as many patients are unable to produce sputum. This means that many patients are treated on the basis of clinical findings and...
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Use of Whole Genome Sequencing for Mycobacterium tuberculosis Complex Antimicrobial Susceptibility Testing
pubmed.ncbi.nlm.nih.gov
Whole genome sequencing (WGS) is becoming an important diagnostic tool for antimicrobial susceptibility testing of Mycobacterium tuberculosis complex (MTBC) isolates in many countries. WGS protocols...
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Use of Whole Genome Sequencing for Mycobacterium tuberculosis Complex Antimicrobial Susceptibility Testing: From Sequence Data to Resistance Profiles
pubmed.ncbi.nlm.nih.gov
Whole genome sequencing of Mycobacterium tuberculosis complex (MTBC) isolates has been shown to provide accurate predictions for resistance and susceptibility for many first- and second-line anti-t...
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Three-Dimensional Rotary Culture to Model Mycobacterial Biofilms in Low-Shear Detergent-Free Liquid Suspension
pubmed.ncbi.nlm.nih.gov
In vitro biofilm models have allowed researchers to investigate the role biofilms play in the pathogenesis, virulence, and antimicrobial drug susceptibility of a wide range of bacterial pathogens....
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Mycobacterium wolinskyi infection after breast augmentation: A case report and comprehensive review
pubmed.ncbi.nlm.nih.gov
We present a case report about a 26-year-old female with a Mycobacterium wolinskyi surgical site infection after bilateral breast augmentation. In a unique approach compared with previously reported...
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Backtranslation of human RNA biosignatures of tuberculosis disease risk into the preclinical pipeline is condition dependent
pubmed.ncbi.nlm.nih.gov
Human-derived biosignatures of tuberculosis disease progression were evaluated for their predictive fidelity across preclinical species and derived tissues using available public data sets.
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Development and evaluation of a triplex droplet digital PCR method for differentiation of M. tuberculosis, M. bovis and BCG
pubmed.ncbi.nlm.nih.gov
Our data demonstrate that the established triplex ddPCR method is a sensitive, specific and rapid method for differentiation and identification of M. tuberculosis, M. bovis, and BCG.
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