Luke Turner 🦠
@MicroLukas
Followers
3K
Following
6K
Media
464
Statuses
2K
Clinical Scientist (HSST) @PublicHealthW - Microbiology. Focusing on #AMR and WGS 🧬 Own opinion only. Fictional cases for education #AMStewardship #MedEd
Wales, United Kingdom
Joined April 2022
Cough like Dracula! 🧛 Cover your mouth with your elbow to stop germs from spreading this #Halloween and beyond. This simple move can help keep everyone healthy. 🎃 👻 🦇
152
23
55
Answer: Mero-vabor is preferred as the highest likelihood of emergence of resistance = caz-avi. How does resistance develop? Most often, acquisition of resistance was associated with KPC-3, or KPC-2, isolates harbouring the *D179Y* substitution. https://t.co/0w7ZXkVlwf
1
0
1
For the treatment of KPC-producing infections: IDSA guidelines state that meropenem-vaborbactam is the preferred option over ceftazidime-avibactam. Why is caz-avi thought to be worse?
1
1
6
Updated nomenclature of common Candida species Add Candida auris ⏭️Candidozyma auris. #IDXposts #bookmark
https://t.co/Fd6RPPh424
6
40
111
Antibiotics only version (because they are the most important drugs 👀). Can you get them all? https://t.co/ej5vaHMFZO
3
2
6
R-ofloxacin has very little/limited activity. L-ofloxacin is the active L‑enantiomer of ofloxacin, meaning higher efficacy, better tissue penetration, and often fewer side effects—all at a lower dose. #Pharmacology #Antibiotics
1
0
0
Ofloxacin is a racemic antibiotic—meaning it contains two enantiomers: R-ofloxacin (50%) and L-ofloxacin, aka Levofloxacin (50%).
1
0
0
Answer: Levofloxacin! 💡 Key takeaway: Levofloxacin is essentially the “optimized” version of ofloxacin, giving stronger antibacterial activity with potentially fewer side effects and simpler dosing.
1
0
0
# 5 – Five drugs used to treat syphilis 1. **Benzylpenicillin** First line (IV – neurosyphilis) 2. Procaine penicillin 3. Ceftriaxone 4. Doxycycline (oral – for non-pregnant, pen-allergic patients) 5. Amoxicillin
1
0
1
# 4 – Four treponemal species ➤ Human-infecting **Treponema** species: 1. T. pallidum pallidum – syphilis 2. T. pallidum pertenue – yaws 3. T. pallidum endemicum – bejel 4. T. carateum – pinta *Beware false positives!
1
0
1
# 3 – 33% of MSM transmission is extragenital ➤ In men who have sex with men, up to **one-third** of syphilis infections occur at **oral or rectal sites** — often asymptomatic. Justifies **3-site STI screening** (oral, anal, urethral).
1
0
0
# 2 – Secondary syphilis occurs in ~25% ➤ Without treatment, **about 25%** of people with primary syphilis develop **secondary syphilis**: rash (palms/soles), condylomata lata, fever, lymphadenopathy.
1
0
0
Five things on Syphilis - By the numbers: # 1 – One painless chancre ➤ Primary syphilis: Classically **a single painless ulcer** (chancre), usually at the site of sexual contact. Highly infectious but often unnoticed. (Chancres may also be multiple, painful)
1
0
5
🦠 Brucellosis — acute or chronic, with fever, fatigue & back pain. 📘 What do the latest lab guidelines say about identifying Brucella? 🎙️ Tune in: https://t.co/ECEsYQjCrn
#Brucella #Microbiology #LetsTalkMicro #ClinicalMicrobiology
0
2
8