Meloni Lab
@MeloniLab
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We study the structure, reactivity and function of metalloproteins involved in transition metal homeostasis. *Student-run account
University of Texas, Dallas
Joined March 2022
Our strategy for the enantioselective total syntheses of vallesamidine and the schizozygane alkaloids is out in @J_A_C_S!!! Congrats to Krishna and @ZurwaCheema! @UTDallasChemBio @WelchFoundation @CPRITTexas @UTDallasNews @TotalSynthesis @TotalSyntheses
pubs.acs.org
A general streamlined strategy for the enantioselective total syntheses of the schizozygane family of natural products and related alkaloid vallesamidine is described. Specifically, a catalytic...
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I'm thrilled to shared my very first scientific publication 🥳 MctB and CtpV are two transmembrane proteins from M.Tuberculosis. In this work the two proteins were used as antigens in a new thermostable vaccine formulation.
pubs.acs.org
Tuberculosis is one of the deadliest infectious diseases and continues to be a major health risk in many parts of the world. Even today, the century-old Bacillus Calmette-Guerin (BCG) vaccine is the...
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Congratulations to Jonathan Martinez-Garcia (@Jony_Chem) and Dr Sneha Kumari (@Snekumari) , as well as to all authors!
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The proteoliposomes were coated in a MOF shell to confer the vaccines with thermo and chemical stability. The results are promising to address the global burden of Tuberculosis disease.
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In this work, in collaboration with the Gassensmith Lab, two transmembrane proteins from Mycobacterium Tuberculosis were reconstituted into proteoliposomes and tested as the antigens in a new vaccine formulation.
pubs.acs.org
Tuberculosis is one of the deadliest infectious diseases and continues to be a major health risk in many parts of the world. Even today, the century-old Bacillus Calmette-Guerin (BCG) vaccine is the...
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Congratulations to Jonathan MartÃnez (@Jony_Chem ) for receiving the ACS Pride Merck Graduate Research Award!
Congratulations to the seven 2025 ACS Pride Merck Graduate Research Award recipients! Read more here: https://t.co/HT5FqvyG6q Stay tuned for more information as the seven will speak at the 2025 ACS Spring Meeting in San Diego. #QueerInSTEM #STEMPride #ResearchExcellence #Award
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Our paper on the catalytic prenyl conjugate additions for synthesis of enantiomerically enriched PPAPs is out today in @ScienceMagazine Great collaboration with @HoveydaLab & @pengliu_group
@CPRITTexas @UTDallasChemBio @UTDResearch
https://t.co/NvN1TS6LIx
science.org
Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of >400 natural products with a broad spectrum of bioactivity, ranging from antidepressant and antimicrobial to anti-obesity and...
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Attending and giving a talk at #ACSFall2024 was a dream come true. Many thanks to @UTDScience for my travel award.
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Had a great time at #ACSFall2024 and presented my research at Bioinorganic Chemistry from Cell to Organism session. I am grateful for ACSDIC for the travel award and @MeloniLab for the opportunity.
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I had the absolute pleasure of presenting my work at the #ACSFall2024 meeting, and am glad to be the recipient of the ACS Biological Chemistry Travel Grant.
It was an absolute thrill meeting our #ACSDBC student awardees for #ACSFall2024! Excellent science all around!
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Congratulations to our student travel awardees for #ACSFall2024! The #ACSDBC helps sponsor #gradstudents and #postdocs to travel to each @AmerChemSociety meeting to present their research in BIOL sessions. Check here and our website to learn more: https://t.co/SV5sgmhwf9
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We had a terrific time in Colorado! Congratulations to Madujika, Fernando, Humera, Luciano and Mitchell who gave great talks and posters presentations! #ACSFall2024
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#ACSFall2024 is just around the corner and we hope you can attend some of the talks and poster presentations that some of our lab members will deliver in Denver!
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The latest book chapter from our group is finally out! Here, we describe our fluorescence-based method to study real time transport of transition metals in proteoliposomes. Congrats to Mitchell, Rose, Humera and Madujika who led this work!! https://t.co/6Hbp6Fb6kA
link.springer.com
Transmembrane transition metal transporter proteins are central gatekeepers in selectively controlling vectorial metal cargo uptake and extrusion across cellular membranes in all living organisms,...
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Madujika A. Horadigala and Humera Gull had a great time presenting their grad work at the 2024 Membrane Transport Proteins #GRC @GordonConf
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