Meloni Lab
@MeloniLab
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We study the structure, reactivity and function of metalloproteins involved in transition metal homeostasis. *Student-run account
University of Texas, Dallas
Joined March 2022
RT @filippo_romiti: Our strategy for the enantioselective total syntheses of vallesamidine and the schizozygane alkaloids is out in @J_A_C_….
pubs.acs.org
A general streamlined strategy for the enantioselective total syntheses of the schizozygane family of natural products and related alkaloid vallesamidine is described. Specifically, a catalytic...
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RT @Jony_Chem: I'm thrilled to shared my very first scientific publication 🥳 MctB and CtpV are two transmembrane proteins from M.Tuberculos….
pubs.acs.org
Tuberculosis is one of the deadliest infectious diseases and continues to be a major health risk in many parts of the world. Even today, the century-old Bacillus Calmette-Guerin (BCG) vaccine is the...
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Congratulations to Jonathan Martinez-Garcia (@Jony_Chem) and Dr Sneha Kumari (@Snekumari) , as well as to all authors!.
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The proteoliposomes were coated in a MOF shell to confer the vaccines with thermo and chemical stability. The results are promising to address the global burden of Tuberculosis disease.
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In this work, in collaboration with the Gassensmith Lab, two transmembrane proteins from Mycobacterium Tuberculosis were reconstituted into proteoliposomes and tested as the antigens in a new vaccine formulation.
pubs.acs.org
Tuberculosis is one of the deadliest infectious diseases and continues to be a major health risk in many parts of the world. Even today, the century-old Bacillus Calmette-Guerin (BCG) vaccine is the...
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Congratulations to Jonathan MartĂnez (@Jony_Chem ) for receiving the ACS Pride Merck Graduate Research Award!.
Congratulations to the seven 2025 ACS Pride Merck Graduate Research Award recipients! Read more here: Stay tuned for more information as the seven will speak at the 2025 ACS Spring Meeting in San Diego. #QueerInSTEM #STEMPride #ResearchExcellence #Award
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RT @filippo_romiti: Our paper on the catalytic prenyl conjugate additions for synthesis of enantiomerically enriched PPAPs is out today in….
science.org
Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of >400 natural products with a broad spectrum of bioactivity, ranging from antidepressant and antimicrobial to anti-obesity and...
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RT @PerezMedinaLu: Attending and giving a talk at #ACSFall2024 was a dream come true. Many thanks to @UTDScience for my travel award. https….
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RT @MadujikaA: Had a great time at #ACSFall2024 and presented my research at Bioinorganic Chemistry from Cell to Organism session. I am gr….
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RT @MerroGull26: I had the absolute pleasure of presenting my work at the #ACSFall2024 meeting, and am glad to be the recipient of the ACS….
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RT @ACS_DivBioChem: Congratulations to our student travel awardees for #ACSFall2024! The #ACSDBC helps sponsor #gradstudents and #postdocs….
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We had a terrific time in Colorado! Congratulations to Madujika, Fernando, Humera, Luciano and Mitchell who gave great talks and posters presentations! #ACSFall2024
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#ACSFall2024 is just around the corner and we hope you can attend some of the talks and poster presentations that some of our lab members will deliver in Denver!
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The latest book chapter from our group is finally out! Here, we describe our fluorescence-based method to study real time transport of transition metals in proteoliposomes. Congrats to Mitchell, Rose, Humera and Madujika who led this work!!.
link.springer.com
Transmembrane transition metal transporter proteins are central gatekeepers in selectively controlling vectorial metal cargo uptake and extrusion across cellular membranes in all living organisms,...
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Madujika A. Horadigala and Humera Gull had a great time presenting their grad work at the 2024 Membrane Transport Proteins #GRC @GordonConf
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