
Meller Lab
@MellerLab
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Happy to share our lab team's new paper in the Advanced Materials journal. check it out online : .
advanced.onlinelibrary.wiley.com
Rapid full-length, single protein molecules separation, tracking, and identification in ultra-high aspect ratio silicon devices. Proteins are tagged by chemo-selective dual amino-acid specific...
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Very nice progress towards whole proteins fingerprinting using solid-state nanopores by our PhD student Neeraj @Neeraj_Soni_ and the team, appeared in @acsnano here is the link: ๐.
pubs.acs.org
The ability to routinely identify and quantify the complete proteome from single cells will greatly advance medicine and basic biology research. To meet this challenge of single-cell proteomics,...
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Finally - our nanopore-based SARS-CoV-2 sensing paper using clinical samples is out. Great ๐๐ป job, team!! Check it out:
pubs.rsc.org
The majority of RNA based COVID-19 diagnostics employ enzymatic amplification to achieve high sensitivity, but this relies on arbitrary thresholding, which complicates the comparison of test results...
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How many photons needed to discriminate two fluorophores with identical emission spectra? A nice preprint from the lab by our student Maisa Nasser just appeared on line in iScience:
cell.com
Computational chemistry; Optics; Biophysics; Laser biophysics
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Congratulations to Eran on his ACS Nano paper reporting fast and deterministic nanopore drilling
meller-lab.net
In a latest publication, we develop a custom algorithm (called NLDA) and software to deliver a deterministic fashion of sub-nanopore laser drilling. We provide a full recipe to obtain the fabricated...
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Finally- our collaborative perspective paper on the emerging proteome sensing technologies is out: thanks to all the contributors !.
nature.com
Nature Methods - This Perspective describes new single-molecule protein sequencing and identification technologies alongside innovations in mass spectrometry that will eventually enable broad...
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