
Melikian lab
@MelikianLab
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Joined February 2020
A postdoctoral position is available to study enveloped virus entry using quantitative microscopy techniques, such as single particle tracking, image correlation and super-resolution imaging.
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Dear @VP @KamalaHarris: Break your month-long silence. Take action to break oil-rich #Azerbaijan’s blockade of 120,000 indigenous Christian Armenians in #Artsakh. Stop US military aid to Azerbaijan, start US humanitarian aid to Artsakh. #ArtsakhTweet.
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Congratulations @AshwanthFrancis for publishing his latest results @NatureComms demonstrating that nuclear speckles provide an architectural basis for nuclear homing of HIV-1 replication complexes and subsequent integration into associated genomic loci.
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RT @YountLabOSU: Major breakthroughs from the Melikyan Lab in understanding how IFITM3 inhibits viral membrane fusion through altering mech….
biorxiv.org
Interferon-induced transmembrane protein 3 (IFITM3) potently inhibits entry of diverse enveloped viruses by trapping the viral fusion at a hemifusion stage, but the underlying mechanism remains...
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RT @MelikianLab: Here we suggest HIV Env glycoproteins form clusters in the membrane of mature viruses, and SER5 (not SER2) disrupts Env cl….
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We would like to thank @HHMIJanelia for helping us with 3D super-resolution imaging iPALM, and imaging core at GaTech with 2D dSTORM to visualize how HIV Envelope glycoproteins and SERINC5 distribute on single viruses.
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We published our exciting findings on ACS Nano! Using super-resolution fluorescence imaging to study how recently discovered SERINC5 (Serine Incorporator Protein 5) inhibits HIV-1 fusion. #HIV #SERINC5 #superresolution #singlevirusimaging.
pubs.acs.org
Serine incorporator protein 5 (SERINC5) is the host antiretroviral factor that reduces HIV-1 infectivity by incorporating into virions and inhibiting the envelope glycoprotein (Env) mediated virus...
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RT @SRMicro_papers: Super-Resolution Fluorescence Imaging Reveals That Serine Incorporator Protein 5 Inhibits Human Immunodeficiency Virus….
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