Max Z. Y. J. Chien
@MaxZYJChien
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PhD student at @UCLIoN & @TheCrick in @FrattaLab
London, England
Joined January 2019
We are finally here. Thanks to @OscarWilkins16 and @FrattaLab gave me this wonderful chance to participate in this fantastic research. Creation of de novo cryptic splicing for ALS and FTD precision medicine | Science
science.org
Loss of function of the RNA-binding protein TDP-43 (TDP-LOF) is a hallmark of amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders. Here we describe TDP-REG, which exploits the...
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RT @OscarWilkins16: We're looking for someone with a creative mindset and excellent modern molecular biology skills (DNA manipulation, Illu….
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RT @OscarWilkins16: New BioRxiv paper on using cryptic splicing to unlock precision gene therapy activation for ALS, FTD & other TDP-opathi….
biorxiv.org
A system enabling the expression of therapeutic proteins specifically in diseased cells would be transformative, providing greatly increased safety and the possibility of pre-emptive treatment. Here...
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Chinese very soon😂🤣🤣.
Guy got rejected in front of 3000 people😳. I still believe in him tho. Whole video on my YouTube.
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