Mattia Ghirardello
@MattiaGhirarde2
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Researcher in glycochemistry with interest in nanoparticles, vaccines, and multivalency
Joined April 2022
RT @RamonHu08403543: Excited to share our latest work on engineering Tn/STn-specific antibodies from a shared germline scaffold! Grateful f….
nature.com
Nature Chemical Biology - Structural studies of certain Tn and STn antigen-targeting antibodies reveal that their VH and VL domains recognize the glycan antigen and the adjacent peptide region,...
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RT @JMLdeLuzuriaga: Very happy to share that our work in Nanoscale Advaces has been included in the Popular Advances collection.@Irene_delC….
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RT @MCGalan_Bristol: Hot of the press: are you interested in Carbon Dots as an Emergent Class of Sustainable Antifungal Agents. Check out o….
pubs.acs.org
Carbon-based functional nanomaterials with distinct photoluminescent properties have gained significant attention for their diverse applications in bioimaging, biomedicine, and antimicrobial treatm...
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Happy to share our last publication! We developed a super-sensitive probe for the detection of sialic acids in biological samples. A great collaboration between the @bifi_unizar, the @MCGalan_Bristol (@BristolUni) and the Voglmeir group.
pubs.acs.org
Sialic acids (Sias), consisting primarily of N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc), play crucial roles in many biological processes. The detection and quantification...
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RT @pcorzana: New collab from our group @unirioja with @MattiaGhirarde2, Ana Guerreiro, V. Mangini & G. Bernardes. We show that lowering MU….
chemistry-europe.onlinelibrary.wiley.com
The synthesis of multicomponent cancer vaccines on AuNP carriers could be rationalized by the simultaneous functionalization of the antigen and immunomodulator components on the same particles....
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RT @_miguelmonge: Great front cover showing the work by @Irene_delCampo PhD work. Congrats to all collaborators!!.@JMLdeLuzuriaga @pcorzana….
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RT @JMLdeLuzuriaga: Fantastic collaboration with @pcorzana @MattiaGhirarde2 @MCGalan_Bristol N. Allen now published in Nanoscale Advances h….
pubs.rsc.org
Thiolate-protected gold nanoclusters (AuNCs) of sub-2 nm size have been synthesized through a novel bottom-up approach using the organometallic precursor [Au(C6F5)(tht)] (tht = tetrahydrothiophene)...
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RT @ARAID_ES: L@s 3 investigadores que han recibido una ayuda de @ContraCancerEs son:. 1⃣Mattía Ghirardello @MattiaGhirarde2 @bifi_unizar….
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RT @JaviRamSor: And finally. it is out! Our latest work on Glycan-Silica Nanoparticles as Effective Inhibitors for Blocking Virus Infectio….
pubs.acs.org
Small solid silica nanoparticles (SiNPs) have been used for multivalent carbohydrate presentation in DC-/L-SIGN-mediated viral infection models. Glycosylated SiNPs (glycoSiNPs) were fully character...
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RT @eurocarb22: 📢 For the first time in history, the Emil Fischer Award will be presented to two outstanding scientists! 🏆👏. At @Eurocarb22….
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RT @JACS_Au: A continuous microfluidic glycosylation strategy combining imidazolium-based chromatography-free purification and in situ MS r….
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RT @MCGalan_Bristol: Looking for an interdisciplinary PhD position at the chemistry/biomedical interface to help develop early diagnostics….
findaphd.com
PhD Project - One Inter-Disciplinary PhD Studentship on Early Detection of Brain Cancer at University of Bristol, listed on FindAPhD.com
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RT @hebusto: Hoy despedimos en el grupo de #QuímicaBiológica de @unirioja a @MattiaGhirarde2. Se nos va para continuar con su carrera inves….
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RT @hebusto: Fantástica representación del grupo de Quimica Biológica de @unirioja #IQUR en #Glycobasque7. Fotos de la sesión del viernes 8….
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RT @MCGalan_Bristol: Looking for ways to fight AMR? see our paper on C2-Linked Araf-coated Microbeads to Selectively Target S. aureus. Grea….
pubs.acs.org
Carbohydrates play pivotal roles in the first stages of microbial infections and can be exploited as decoys to hijack the interactions between bacteria and the host cell. Multivalent glycan probes...
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RT @angew_chem: Non-Natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity (Goncalo J.….
onlinelibrary.wiley.com
A chemically defined vaccine is prepared by combining the structural design of a non-natural glycopeptide antigen with a site-specific protein modification. The resulting vaccine, which contains a...
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RT @aglez_tf: Check out our latest publication just accepted in @JACS_Au - It turns out aromatics, when confronted with neutral sugars, are….
pubs.acs.org
CH/π bonds are versatile elements for the construction of complex molecular architectures, thus playing key roles in many biomolecular recognition processes. Although seldom acknowledged, aromatic...
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RT @MCGalan_Bristol: Happy to share our latest work on the Microfluidics-Based Ionic Catch and Release Oligosaccharide Synthesis (ICROS-Mic….
pubs.acs.org
A continuous microfluidic glycosylation strategy that requires no chromatography between steps and significantly expedites glycosylation chemistry is described. This practical approach incorporates...
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