Mark Bicket, MD, PhD, FASA
@MarkBicket
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Health Leader, Physician Anesthesiologist, Clinical Investigator @UMichAnesthesia • Working to improve #pain care and patient outcomes • Husband, Dad, #GoBlue
Ann Arbor
Joined June 2009
⏰ Time is running out to save on #ASRAFALL25 registration! Sign up by Thursday, September 18 to take advantage of discounted rates for the upcoming meeting in Austin, TX. We can't wait to see you all soon! https://t.co/W9EWeQXMG8
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The Chronic Pain & Fatigue #Research Center at @UMich is seeking applications for the HEAL National K12 Clinical Pain Career Development Award! Download additional info: https://t.co/wGLLG1pwMK Register for informational webinar held 9/15 @ 4-5pm EDT: https://t.co/2cGocpMryI
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Many thanks to Brian Bateman at @stanfordanes for collaborating on this piece Citation: Bicket MC, Bateman BT. Long-Term Opioid Therapy for Pain: What Is Known About Harms—and Still Not Known About Benefits. JAMA. Published online August 27, 2025. doi:10.1001/jama.2025.13225
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The takeaway: Prescription opioid harms are higher than we thought. But without robust data on benefits, risk mitigation will always be incomplete. What’s the first step toward balanced, safe, and compassionate opioid policy and pain care? 👇 [10/11]
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Read the full @JAMA_current commentary: 👉 https://t.co/4VunOarYsk How should @US_FDA, clinicians, and patients respond? Join the discussion—rigorous data should guide the next phase of opioid policy. [9/11]
jamanetwork.com
This Viewpoint discusses recent US Food and Drug Administration data on opioid-related risks and harms; highlights ways in which understanding of these risks and harms remains incomplete; and calls...
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Clinicians are left in limbo. They have detailed risk data—but still lack comparable evidence on long-term benefit. It’s like reading only one side of the story [8/11]
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Patients are caught in the middle. 1 in 5 long-term users faces elevated addiction risk— yet many share stories of meaningful relief that helps them function. Both matter. [7/11]
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FDA recently called for updated opioid labeling: https://t.co/fr6vGbjg0T That’s movement—but only half the problem. We also must avoid reflexive de-prescribing & forced tapers, which carry risks of mental health harms, suicide, & even death. [6/11]
fda.gov
FDA Requires Major Changes to Opioid Pain Medication Labeling to Emphasize Risks
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Would you be surprised to know these data come from studies run by opioid manufacturers—under FDA oversight? Here’s the real catch: the focus has been on harms, with far less progress on whether opioids provide long-term benefit. Docs: https://t.co/AoM9xDFs74 [5/11]
fda.gov
May 5, 2025: Joint Meeting of the Drug Safety and Risk Management Advisory Committee and the Anesthetic and Analgesic Drug Products Advisory Committee Meeting A
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New data from FDA-required studies: -> 20% report misuse within 1 year of long-term use -> 27% of long-acting users meet OUD criteria -> Overdose: up to 4% within 5 years The burden is larger than most realized. [4/11]
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Prescribing has plummeted since 2012: -> Long-acting prescriptions fell 41% (22.8M → 9.3M) -> Short-acting fell 49% 📉 The sharpest declines in 3 decades—yet harms remain stubbornly high. [3/11]
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Overdose deaths declined last year—progress worth noting. But don’t mistake that for resolution: prescription opioids still carry risks that are larger, clearer, and more serious than ever. [2/11]
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Prescription opioid harms are worse than the headlines suggest. Our new JAMA Viewpoint shows where FDA oversight hasn’t kept pace—and how to fix it. https://t.co/4VunOarYsk 🧵 [1/11]
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I’m excited to speak at the upcoming @ASRA_Society webinar on Cannabis and Surgery this Tuesday, June 10, from 4-5 pm ET with @dr_rajgupta and Dr. Asike Join us to explore the impact of cannabinoids on surgical care. Anesthesiologists, surgeons, physicians, nurses, and anyone
asra.com
The next @ASRA_Society webinar is next Tuesday, June 10 at 4 pm and will cover #cannabis in surgery! Learn to differentiate common #cannabinoids and understand how they may impact perioperative care. Free for anyone to attend live as long as you RSVP! https://t.co/IhT8j9KMKL
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#Anesthesiology scientists take note - applications for FAER’s Fall 2025 Grant Cycle are now open! Available #FAERgrants include the Mentored Research Training Grant, Research in Education Grant, and Research Fellowship Grant. Learn more & apply at https://t.co/25L8sUXj00!
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https://t.co/jMox24bz8p Congrats to the 2025 recipients of the Advanced Medical Student Research Fellowship!🥳 Building on the #FAERmsarf program, Mr Greene & @rebeccanikatsai will spend up to 1yr focusing on #anesthesiology #research & receiving further training via the AMSRF
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“Becoming an Anesthesiologist-Scientist” is only 1 week away! Presented by FAER & @A_P_S_A, this webinar offers insights from #FAERgrantees & leaders on how to thrive when pursuing #anesthesiology #research. Don’t miss out – register at 5/22 at the link: https://t.co/Ehi9QFmFUm
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📚As I've prepared for each talk within the #PainAndResiliency Series, @michigan_open's resources have been so helpful! 🔎Check out their guide to reducing #SUD stigma! https://t.co/hpklj4OlzX
#MSCGC @ASALifeline @MsMichellesHere #Match2026 #anesthesia @drchadb @MarkBicket
Join Drs. Ariana Nelson and Sudheer Potru for a thoughtful discussion on addressing the stigma of #SubstanceUseDisorder and caring for patients with #ChronicPain. Spots are limited—register now: https://t.co/6y1r7cIVfL
#MSCGC #PainAndResiliency
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Chronic pain affects 1 in 5 Americans—time to shine a spotlight on solutions. Grateful to share advances in pain for primary care at #IM2025 in New Orleans today with @ACPIMPhysicians . Bonus: bumped into former @HopkinsMedicine classmate Jim O’Keefe in the crowd!
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🚨#Research🤝 #Advocacy Join us on Tues 4/1, 7 pm CT as @dr_tinadoshi and Dr. Max Kelz discuss how to get involved in research & its direct impact on patient advocacy! Spots are limited. Networking to follow @ACCMResidency @PennAnesthesia #anesthesia #PainAndResiliency #MSCGC
Medical students: Join Drs. Tina Doshi and Max Kelz for the next event in our #PainAndResiliency series! Learn how to get involved in research and the role that research plays in patient advocacy. Register now: https://t.co/9cx4ul0wLK
#MSCGC
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