Moi Expósito-Alonso (#MOILAB)
@MExpositoAlonso
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Researching from mutations to climate change • Prof at @UCBerkeley @Cal + Freeman Hrabowski Scholar @HHMInews • In 💚 w California 🌲🌱 🌵• ✊🏾🏳️🌈 💔🇮🇱🇵🇸
Berkeley, CA
Joined July 2014
Excited to release a huge evolution project on the works for many years:. An experimental evolution project across climates to understand rapid adaptation. Preprint: All data available: #MOILAB.@UCBerkeley @HHMINEWS . 🧵👇.
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RT @MExpositoAlonso: Excited to release a huge evolution project on the works for many years:. An experimental evolution project across cli….
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Amazingly thankful to consortium who persevered for years to run the experiments!. And dream team Xing Wu and Tati Bellagio for final analyses/writing, Meixi and Lucas for comp. analyses, Ru Peng for enormous data, and +++ others!.
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Our big dataset let us to test whether evolution in a novel environments was predictable from the rest of the data.We found early warning signals to anticipate if populations will adapt and persist or not – important lessons to incorporate evolution to biodiversity forecasts!
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We tested whether such gene trajectories could have been predicted – we found genetic variants from warm regions of the species, increased in frequency in experimental evolution plots in warm outdoor locations, allowing us to build models
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We search along the A. thaliana genome the trajectories of genetic variants that correlated with climate, identifying genes likely involved in climate adaptation
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Remarkably, we found that those genotypes that showed high specialization, may have lagged behind adaptation in the last decades of climate change, because they often performed better when transplanted to cooler environments than where they were collected from
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We could explain some of the patterns of which genotypes increased or decreased in frequency over time based on signals of local adaptation, where genotypes that had evolved in similar environments performed the best when transplanted - and modeled their climatic niches!
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But we evolution occurred differently in different outdoor evolution experiments, with some locations having erratic trajectories and others being highly repeatable
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We find clear evidence of rapid evolution, where populations diverged at the genomic level from the start pool over years!
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Summary: In just a few years of planting genetically diverse Arabidopsis thaliana in the field, we found signs of rapid evolution across different climates, identified novel genes connected with climate adaptation, and tested the predictability of evolution!
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RT @sarameghanbeery: The AI for wildlife conservation community has been impacted by recent layoffs in the US public sector; many conservat….
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Joanne Chory was a giant of plant genetics, and I hope she will keep inspiring a generation of plant biologists to study fundamental questions of biology . and then think big. Thanks Joanne.
🌿 Today, we remember Salk Professor Joanne Chory, a visionary plant biologist and a force for climate action. Her research revolutionized how we understand plant biology and inspired solutions to fight climate change. Joanne’s brilliant mind and passion will forever impact the
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RT @salkinstitute: 🌿 Today, we remember Salk Professor Joanne Chory, a visionary plant biologist and a force for climate action. Her resear….
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RT @MExpositoAlonso: We just posted a new paper in @bioRxiv providing the first comprehensive estimates of global genetic diversity loss. J….
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One key challenges for biodiversity monitoring at @UNBiodiversity #COP16 is *where species are*. @leg2015 led a AI deep learning approach to map species at high resolution using California as example. Published at @PNASNews . #COP16 ping me to chat!
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RT @ksmualim: Would highly recommend this API for anyone interested in understanding how genetic diversity (pi) changes with Fst, migration….
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Picture is grim, but we have the tools to plan and anticipate what will happen and how to solve it. If there is will there is a way . to bend the curve of biodiversity loss #COP16. Shoutout to authors Kristy Mualim, Jeff Spence, Clemens Weiss, Oliver Selmoni, Meixi Lin!
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Take home 3.- Even if all populations are protected now, genetic diversity will continue dramatically declining for decades centuries. We need restoration.
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Take home 2.- The majority of genetic diversity will be lost due to the loss of area/populations of species. Many species even if not endangered have lost part of their land, and this is typically ignored.
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