
MANDRAKE
@MANDRAKE_LAB
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MANchester DRug Analysis & Knowledge Exchange. Award winning partnership working to deliver effective harm reduction through excellence in science.
Greater Manchester, UK
Joined July 2017
💥BREAKING!💥 25 Jun 25 . Our founders @sutcliffeob & @andyc1864 are honoured to be co-awarded the RSC Analytical Science Horizon Prize for the collaborative project, led by @CRPudney, on the application of portable technologies for drug detection, policing & harm reduction.
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RT @sutcliffeob: 💥BREAKING!💥 26 Aug 2025. Rob Ralphs @MMUOutofit and my #Spice (#SCRAs, synthetic cannabinoids) “Primer”, first published i….
theconversation.com
New psychoactive substances, same problematic users.
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RT @ManchesterPride: ⚠️CAUTION!⚠️ 23 Aug 2025. Back-of-house substance testing by @MANDRAKE_LAB has found multiple samples of synthetic #ca….
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💥NEW RESEARCH PAPER💥 . Our international collaboration w/ @ShimadzuUK & the @FRNSCPSU @penn_state university on the development of RP-UHPLC & HILIC approaches to the analysis of regioisomeric fluorofentanyl derivatives is now available (free) online:
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Headline Findings:. 💥454 vapes tested, from 27 schools. 💥17.4% had synthetic cannabinoid receptor agonists (SCRAs or Spice) present (78% schools). 💥We think these are being missold/supplied as THC. Link (open access) to paper 👇.
onlinelibrary.wiley.com
Background and aims People who use synthetic cannabinoids (SCs) report debilitating side effects and withdrawal symptoms, coupled with dependence. In the UK, SC use was believed to be largely...
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Honoured to be involved in this important study to “lift the lid” on the prevalence, chemical analysis and to promote/effect harm reduction associate with these harmful products in UK schools.
💥NEW RESEARCH PAPER💥. Our collaborative work with @UniofBath/@BristolUni, led by Tom Freeman @JScottUoB & @CRPudney, on the analysis of synthetic cannabinoids in e-cigarettes seized from English schools has been published (open access) in @AddictionJrnl.
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The team is proud to be part of this amazing multidisciplinary global team including academic, law enforcement and industrial experts. This award highlights the importance of strong collaborations to effect change and promote harm reduction. Read more:
mmu.ac.uk
Ground-breaking research into the identification of synthetic drugs to advance policing and harm reduction recognised by Society
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Our Director @sutcliffeob spoke about rapid, cost-effective chemical analysis to monitor drug trends & promote harm reduction @ISSDrugPolicy Conference in Manchester. Also the team were honoured to host a delegation of international attendees at our labs.
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RT @unodc_lab: 🚨 Four potent synthetic opioids are now under international control:.1. N-pyrrolidino protonitazene.2. N-pyrrolidino metonit….
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💥BREAKING!💥4 June 25. The team is #proud to announce that our #PUBLIC #FUNDING has been renewed. Our #scientists are honoured to continue to safeguard the 1.1M residents, across Tyne & Wear, and reduce drug-related harms through our nationally-recognised #harmreduction model.
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Great to see Molly’s research on #synthetic #cannabinoid analysis - in collaboration with @Shimadzu & @ShimadzuUK - get showcased at this prestigious #international conference. Proud to continue our strong industrial partnership. Well done all!.
💥BREAKING💥 2 June 2025. Our collaborative research with @ShimadzuUK on analysis of cannabinoid-containing fluids in illicit vaping cartridges using #mass #spectrometry will be showcased by Dr Alan Barnes at the #ASMS2025 conference in Baltimore. Link:
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RT @sutcliffeob: 💥NEW RESEARCH PAPER💥. Our collaborative work w/ @UniofBath led by @mindnumbed @TomSFHaines & @CRPudney on field-portable t….
pubs.acs.org
Novel psychoactive substances (NPS) pose one of the greatest challenges across the illicit drug landscape. They can be highly potent, and coupled with rapid changes in structure, tracking and...
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Heartfelt congratulations Emily on successfully completing your #Masters by #Research. Well done! The entire team wishes you all the best for the future. You will be missed.
💥BREAKING💥13 May 2025. Many congratulations to Emily Dawber on conferment of her #Masters today. Well done!. Dr @RyanMewis, Dr Jim Pritchett & I are extremely proud of your hard work both in your research and for your dedication to @MANDRAKE_LAB’s harm reduction activities.
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⛔️CAUTION!⛔️ 03 May 2025. Multiple examples of high content #Ecstasy tablets analytically confirmed by @MANDRAKE_LAB, to contain #MDMA (254 - 264 mg/tablet) = to 2½ - 3x the common oral dose circulating in #Manchester. If unwell please seek medical attention.
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💥TESTING DATA💥 Mar 2025. A quick snapshot of recent @MANDRAKE_LAB testing data, of frequently encountered “Ecstasy” pill/tablet types, from across Greater Manchester’s NTE venues. MDMA (as salt) content was determined by GCMS using primary reference std & expressed in mg/tab.
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⚠️WARNING!⚠️ 29 Mar 25. Multiple samples of beige powder, potentially mis-sold as MDMA, confirmed by @MANDRAKE_LAB, to contain synthetic cathinone, 4F-α-PVP, in #Manchester. Not much known about this substance but has been implicated fatalities. If unwell seek medical attention.
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⛔️CAUTION!⛔️ 27 Mar 2025. Multiple, Blue “Moncler” embossed #Ecstasy tablets analytically confirmed by @MANDRAKE_LAB, to contain #MDMA (average: 277 mg/tablet) = to 3x the common oral dose circulating in #Manchester. If unwell please seek medical attention.
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