Loukas Kakoullis ๐ฆ ๐ด๐ฆ
@LoukasMD
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Chief Resident @MAHIMRes Clinical Fellow @Harvardmed Aspiring Epidemiologist & Antimicrobial Steward Tropical Medicine enthusiast Tweets are not medical advice
Boston, MA
Joined December 2019
ACP is honoring six chief residents as winners of the Herbert S. Waxman Chief Resident Teaching Scholarships at #IM2025. The winners will help teach popular Clinical Skills workshops under the guidance and mentorship of expert faculty: https://t.co/DNUjDkVoQz
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Comparative Outcomes of Babesiosis in Immunocompromised and Non-Immunocompromised Hosts: A Multicenter Cohort Study โ
Just Accepted โ๏ธ @LoukasMD @CourtHarrisMD ๐ https://t.co/wErrb6Mn3M
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An achievement I only dared dream of: I will train to become an Infectious Disease physician at Massachusetts General Hospital and Brigham and Womenโs Hospital. To my family, friends, and mentors, your faith in me is what made this possible. You have my gratitude.
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Presenting a rare case: metastatic arthropathy from hepatocellular carcinoma. Highlights the need for thorough diagnostics in atypical joint cases. #ACR24 #BIDMCRheum
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How's this for an AmpC producers mnemonic? "Citrus Cloak in the Air" Citrobacter freundii Enterobacter cloacae Klebsiella aerogenes โCommonly encountered AmpC pathogens. โMisses rarer pathogens in SPACE/SPICE/HECK Yes ๐If any mnemonic was perfect, we'd only have one
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New from @LoukasMD et al: Systematic review: Bronchoscopy outbreaks - Pathogens: P. aeruginosa, M. tuberculosis, NTM, K. pneumoniae, L. pneumophila. Contamination sources: water, scopes, inadequate disinfection. ๐: https://t.co/D0lRWFqZcu
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๐ Stay informed, dissect the correlations, and safeguard against future outbreaks. ๐ฉบ๐งค #MedicalDetectives #OutbreakInvestigation #PathogenPuzzle ๐ฌ
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๐Further clues? Look for inadequate disinfection, contaminated anesthetics, or unclean flasksโour findings can tell you where to look to break the case wide open ๐๏ธ
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๐ฟ Detective Insight 4: Are the culprits Legionella or NTM? Then look at your water sources, whether it's tap water ๐ฐor ice๐ง ๐ซง Also, what have you been cleaning your stuff with? Check if that bronchoscope reprocessor (or its water intake) is teeming with bacteria!๐ฆ
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๐ง Detective Insight 3: Pseudomonas of Klebsiella are your main suspects? Look for bronchoscope defects. ๐ซ๐คฟ
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๐ต๏ธโโ๏ธ Detective Insight 2: If NTM or fungi have been popping up, don't break out the cuffs just yet! ๐ฎThere is a decent chance this is a pseudo-outbreak. ๐ถโ๐ซ๏ธ
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๐ Detective Insight 1: Have you been seeing more Pseudomonas, Klebsiella or TB in your post-bronchoscopy cultures than you expected? Chances are you have an outbreak on your hands! ๐
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๐ซ๐ฆ Is your bronchoscopy suite facing an outbreak? Let us help you where to look! ๐ Our article is your guide to the detective work behind bronchoscopy related outbreaks (23) and pseudo-outbreaks (52).๐ต๏ธโโ๏ธ๐ฉโโ๏ธ @SHEA_Epi @ICHEJournal
https://t.co/SaAI1hKQna
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Enjoyed this? Want to learn more about this #emerging_infectious_disease? Read all about it in our systematic review on #Powassan virus in @TropicalmedMDPI ! @MAHIMRes @DivmeharKaur @victorrvaz @linhchen
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5/ ๐Correlations: 1) Mortality with a) age, b) paralysis, c) respiratory failure. 2) Persistent neurological deficits with a) ataxia, b) paralysis, c) speech disorders, d) cranial nerve involvement. 3) Speech disorders with ataxia. 4) Paralysis with respiratory failure.
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4/ ๐Outcomes: Mortality rate in published cases was 19.1% in adults and 7.1% in children. Mortality rate from CDC is 12.5%, suggesting publication bias. Complications included paralysis and cognitive deficits, often persistent.
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