Lin Huang 黄林
@LinHuang2008
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Principal Investigator, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. , RNA structure, riboswitch, ribozyme, aptamer.
SYSU, Guangzhou , China
Joined May 2012
RT @lilley_mj: There is now a large database of riboswitch structures. In our new Quart Rev Biophys @Biophysics_CUP review, @LinHuang2008 a….
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RT @rsc_chembio: 🚨 LAST CHANCE TO REGISTER FOR #Nucleic25. Don’t miss your chance to join our chairs David Lilley and Wei Yang at an engagi….
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Some general principles of riboswitch structure and interactions with small-molecule ligands | Quarterly Reviews of Biophysics | Cambridge Core -
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RNA catalysis moving towards metabolic reactions: progress with ribozy.
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RT @angew_chem: @LinHuang2008 and team reveals the crystal structures of the theophylline DNA aptamer bound to various ligands. By merging….
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RT @bionaloo: Glad to see the structure of our theophylline DNA aptamer solved by crystallography by Prof. @LinHuang2008. A beautiful struc….
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RT @Fusion_Conf: 📢CONFIRMED SPEAKER LIST REVEALED!📢.Chairs @lilley_mj & Wei Yang have put together a fantastic speaker list for the 8th Nuc….
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RT @LinHuang2008: A general strategy for engineering GU base pairs to facilitate RNA crystallization
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RT @CellDiscovery: Structural basis for #tRNA mimicry by mascRNA and menRNA by Lin Huang @LinHuang2008, Jia Wang & co .
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In these instances of RNA crystallization, GU base pairs were utilized as well.
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A general strategy for engineering GU base pairs to facilitate RNA crystallization
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A general strategy for engineering GU base pairs to facilitate RNA crystallization. Thanks to @lilley_mj @NAR_Open.
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which may lead to better crystallization results. In the field of RNA crystal structures, there are not many methods capable of resolving more than eight independent RNA structures, and our method is one of them.
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Generally speaking, researchers thought that the more stable the RNA is, the better it will crystallize. However, in practical operations, when overly rigid RNA fails to yield ideal crystals, we can consider introducing appropriate flexibility (GU),.
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Time flies and I have been engaged in RNA crystal structure research for nearly 20 years, finally arriving at an opportunity to make methodological contributions. This study combines the concepts of flexibility and overcoming rigidity.
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RT @SophiaBiophys: Our paper is out! Even with all the technological innovations, X-ray analysis remains a powerful and reliable technique….
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