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John Le Quesne Profile
John Le Quesne

@LeQuesneLab

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Mazumdar-Shaw professor of molecular pathology, lung/pleura nut, multiplex imaging devotee, disciple of mRNA translation. #UoG #BICR #pathsoc 🏴󠁧󠁢󠁳󠁣󠁴󠁿🇪🇺

Glasgow, Scotland
Joined March 2011
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@LeQuesneLab
John Le Quesne
11 months
RT @WiringTheBrain: A lot of molecular and cell and developmental biology is concerned with figuring out the "functions" of various protein….
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@LeQuesneLab
John Le Quesne
11 months
It was fantastic having the opportunity to speak at Worldcon 2024 about cancer, and its role as a metaphor in science fiction yesterday. Such a good experiemce - great audience and brilliant questions and discussions. @UofGlasgow @CRUK_SI #WorldCon
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@LeQuesneLab
John Le Quesne
1 year
RT @LabEdwards: @Molly_McKenzie2 has just published her first first-author publication! So much to know about NFkB signaling in this review….
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@LeQuesneLab
John Le Quesne
1 year
Only possible through amazing bioinf from Nicolas Poulain, next-level deep ohenotyping from Leah Officer-Jones and team (@AkoyaBio tech), and superb whole-transcriptome @nanostringtech GeoMx data from the @nigeljamieson group. FFPE rules! @UofGlasgow @CRUK_SI @unibern.
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@LeQuesneLab
John Le Quesne
1 year
Okay so we’re finally getting a handle on how biological plasticity underpins and may cause some of the most deadly morphologies in lung adenocarcinoma, thanks to Hannah Williams’ awesome preprint:.
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@LeQuesneLab
John Le Quesne
1 year
The last few days have been superb. It's been a real privilege to co-lead the TRANSLACORE biobanking training school with Neşe Atabey. The Izmir Biomedicine and Genome Centre have been amazing hosts. Three talks from the world of Scottish tissue research!
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@LeQuesneLab
John Le Quesne
1 year
RT @UofGGovRel: Great to see @LeQuesneLab recognised for his teams work on using AI to ‘learn the language of cancer’ and provide faster di….
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@LeQuesneLab
John Le Quesne
1 year
RT @artsinyc: Curious about AI's potential in Pathology? Discover how self-supervised AI autonomously learns histologic patterns: no need f….
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@LeQuesneLab
John Le Quesne
1 year
RT @keyuan1: So glad to see HPL out. An incredible collaboration with @artsinyc and @LeQuesneLab. Amazing work from @Adalberto_Cq, Nicolas….
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@LeQuesneLab
John Le Quesne
1 year
RT @artsinyc: A fantastic collaboration with @Adalberto_Cq, Nicolas Coudray, @LeQuesneLab, @keyuan1, and more! @glasgowunisrc @nyugrossman.
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@LeQuesneLab
John Le Quesne
1 year
RT @mediaindiagroup: A computer system harnessing #AI to decipher the language of #cancer accurately detects disease signs and offers relia….
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@LeQuesneLab
John Le Quesne
1 year
RT @UofGlasgow: A new AI-powered system developed by researchers at @GlasgowCS, @UofGCancerSci and @nyulangone can spot signs of cancer in….
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@LeQuesneLab
John Le Quesne
1 year
Adal, Nicolas and the team have really changed the game with this study. Interpretable quantitative and immediately useful AI-pathology is here. The implications for both diagnostics and research are huge. #UoG #NYU.
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@LeQuesneLab
John Le Quesne
1 year
I’m so very proud of this work, with my CS colleagues in Glasgow and NYU. The pathology implications are HUGE. Self-learning AI for fully interpretable democratised quantitative H&E image analysis and accurate prognostication.
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@LeQuesneLab
John Le Quesne
2 years
Crucial conclusions from MARS-2. Radical mesothelioma surgery does not extend life. #WCLC
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@LeQuesneLab
John Le Quesne
2 years
RT @keyuan1: What AI can teach us about the nitty-gritty of patterns in pathology slides? We show that self-supervised learning can identif….
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@LeQuesneLab
John Le Quesne
2 years
RT @artsinyc: 🔬Our latest-preprint: self-supervised AI automating histologic pattern discovery and enhancing collaboration with pathologist….
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@LeQuesneLab
John Le Quesne
2 years
Ermagerd. Xenium is alive. Straight out of the box it's UMAPing the hell out of control cells with an optimisation panel. Turns out there's diverse and interesting cell states even in tissue culture. Can't wait to start tackling real questions about tumour function. #10X #Xenium
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@LeQuesneLab
John Le Quesne
2 years
I mean last week. LAST WEEK.
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@LeQuesneLab
John Le Quesne
2 years
We had a day of team-building next week. Note to self- axes to be left outside the door in lab meetings.
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