✨ Regular ovulation is how women make the hormones estradiol and progesterone—important for overall health, not just reproduction. ❌ By suppressing ovulation, most hormonal birth control switches off estradiol and progesterone—and does NOT replace them. #righttoovulate

RT @robkhenderson: "High-earning men overwhelmingly choose to marry highly-educated and high-earning women of a similar age. The idea that….

RT @LongevityTech: Women age differently – and it’s not just hormones. Dr @LaraBriden shares what every woman should know about metabolism,….

That could explain why the same hormonal shifts that are normal for most women can trigger severe mood symptoms in PMDD (and possibly perimenopause). Interestingly, the research focused on GABA receptors in immune cells, expanding the theme of neuroimmune dysfunction in PMDD and.

🧠 Women with severe premenstrual mood symptoms have lower expression of the delta (δ) subunit of the GABA-A receptor during the luteal phase. Because the δ subunit is crucial for responding to progesterone's calming neurosteroid allopregnanolone, reduced expression can make the

RT @GMFHx: Emerging research suggests a complex interaction between the gut microbiome and endometriosis. Here's what you need to know:. ht….

This discovery could pave the way for future ovarian anti-aging treatments, such as:. ⭕Supporting immune resolution and the clearance of cellular debris. ⭕Modulating macrophage activity and reprogramming them to a more anti-inflammatory state.

Specialized macrophages make up to 10% of the ovary’s volume!. They’re there to clean up debris from failed follicles, but over time, they may contribute to inflammation and ovarian aging.

Women with endometriosis-associated infertility are significantly more likely to become pregnant compared to those with infertility from other causes.

Made it to the tip of Africa.

"Biology has a way of humbling and mystifying — if you're open to the data.".

This is me today in Matabo National Park, Zimbabwe. An afternoon walking there left me feeling quite emotional for reasons I can't quite articulate. Like I've been reminded of something important.

There's still a lot to learn, but the overlap between ADHD, hormones, and histamine could be a crucial missing piece in understanding why some women experience such intense premenstrual symptoms.⁠

Importantly, a tendency to high histamine may also be part of the ADHD picture, affecting not just mood and attention but also sensory sensitivity and sleep.⁠.

🌀 Women with ADHD are over 3x more likely to experience PMDD, a severe premenstrual mood disorder.⁠. Several mechanisms could explain this link, including the fact that rising and falling estrogen impacts key neurotransmitters like serotonin, dopamine, and histamine.⁠

Hmm. I did read a lot of Austen as a girl. And then I grew up to be a passionate walker. Coincidence?.

Testosterone also plays a role in brain development during pregnancy. Again, true in both sexes.⁠