An entirely new paradigm for the regulation of mTORC1 is coming, addressing long-standing questions about where and when mTORC1 acts on diverse substrates. Congratulations @DemetriadesLab! Tweet added by Lamming Lab @LammingLab

Lamming Lab

9 months

An entirely new paradigm for the regulation of mTORC1 is coming, addressing long-standing questions about where and when mTORC1 acts on diverse substrates. Congratulations @DemetriadesLab !

Spatially and Functionally Distinct mTORC1 Entities Orchestrate the Cellular Response to Amino Acid...

Amino acid (AA) availability is a robust determinant of cell growth, through controlling mTORC1 activity [1][1]. According to the predominant model in the field, AA sufficiency drives the recruitment...

www.biorxiv.org

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Matt Yousefzadeh

@MattYousefzadeh

9 months

@LammingLab @DemetriadesLab I'll be excited to see the effects of very specific TORC1 inhibitors!

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Brecht D'hoe

@brecht_fit

9 months

@LammingLab @DemetriadesLab @kleinert82

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