🧪NEW PAPER ALERT🧪. Check out our paper in Gut Microbes that sheds light on the role of proteolytic bacteria in inciting inflammation during #colitis, led by @LiamERondeau, the lab's first grad student @FarncombeGI @McMasterU #IBD.Check it out here👇.(⅕).

Marching for gut health, microbes, and a cure! Great morning with @Farncombe_GI friends at the #GutsyWalk to support #IBDResearch and @getgutsycanada

RT @AlbertoCaminer7: Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis @R_JimenezSaiz @LiamERondea….

These findings highlight the potential of targeting microbial proteolytic activity or PAR2 signaling to alleviate inflammation in IBD patients. #IBDResearch #Microbiome #GutHealth @VerduLab @BrunaBLuz (5/5).

Using gnotobiotic and conventional mouse models, we demonstrate that proteolytic microbes that activate PAR2 expand during inflammation, thus worsening colitis through a PAR2-mediated feedback loop. (⅘).

🔍 What is PAR2?.PAR2 is a G-protein-coupled receptor that mediates pro-inflammatory and pro-nociceptive responses when activated by proteases in the gut. Its activation plays a crucial role in the inflammatory response during colitis. (⅗).

Imbalances in host and microbial proteases are linked to IBD. Here, we show that canonical activation of protease activated receptor 2 (PAR2) by proteases is a key signalling event driving inflammation during colitis. (⅖).

RT @machealthsci: We were pleased to welcome @FilomenaTassi and @SoniaLiberal today for a tour of the clinical and research facilities at t….

RT @Giada_DePalma: Great presentation by Alberto at the Basic Science Symposium on GI disease and metabolic health @cddw_clm @AlbertoCamine….

RT @Giada_DePalma: Go Bruna!! Early morning with Student Prizes at @CDDWcanada @McMasterU @AlbertoCaminer7

RT @Gastirueda: Outstanding CAG @CanGastroAssn prize presentations by postdocs @JulienPujo from @Bercik_Collins and Bruna Barbosa from @Lab….

RT @VerduLab: We found Waldo at our Farncombe journal club's Halloween event / team building session where we discussed the consequences of….

RT @VerduLab: Beautiful day for the #gutsywalk in Hamilton! There's still time to donate to support Crohn's and Colitis Canada @getgutsycan….

RT @VerduLab: Check out our bake sale in support of the Crohn's and Colitis Canada #GUTSYWALK. Where: McMaster HSC 3rd floor atrium, blue s….

@AlbertoCaminer7 @MacMedSci @mcmastersgs @MacDeptMed @macmsmg @FFDHRI.

Our lab is recruiting highly motivated graduate students (MSc or PhD)! Check out our research on our website and reach out if you are interested in being apart of our team. @AlbertoCaminer7.

RT @VerduLab: 📢NEW PAPER ALERT 📢. Our latest research published in Gut Microbes sheds light on the role of proteolytic #microbiota in #Croh….

RT @AlbertoCaminer7: Happy to see this study out! We characterized the duodenal microbiota in celiac disease. Sampling site should be consi….

RT @AlbertoCaminer7: Do you want to know more about the role of proteases in infections and common gastrointestinal disorders?.👇👇👇. https://….